Lantana camara (Marie – behind the hospital door) : medicinal properties in alcoholic extraction

Lantana camara (Marie – behind the hospital door, Mari-dèyè-lapôt-Lopital, Marie-derrière la porte de l’Hôpital) — family Verbénacées.

Scientific synonyms : Camara vulgaris Benth, Lantana aculeata-L, L antillana Raf., L aspierata-Vis, L crocea Jacq., L glandulosissima Hayek, L mixta Medik., L montziana f. parvifolia Moldenke, Ltilifolia-Auct non Cham, L undulata Raf., L urticofolia Mill..

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 21 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 196 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Superficial or deep wound, ulcer (leg, diabetic foot), pressure ulcer

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Dash GK (2001)

     Excerpt To study the antihyperglycaemic&d wound healing activity of the leaf extracts of Lantana camara Linn. The wound healing activity was assessed for both leaf juice & hydroalcoholic (ethanol 50% v/v) extract of the leaves on excised rats.

   • According to Ganesh T (2010)

     Excerpt Present study demonstrated that methanol extract of LC leaves exhibit promising anti-hyperglycemic activity against alloxan-induced diabetic rats. Oral administration of the methanol extract of LC (200 & 400 mg/kg body weight) leaves in alloxan-induced diabetic rats, showed significant (P<0.01) reduction in the blood glucose concentration in dose dependent manner.

   • According to Sen S (2010)

     Excerpt Present study demonstrated that methanol extract of LC leaves exhibit promising anti-hyperglycemic activity against alloxan-induced diabetic rats. Oral administration of the methanol extract of LC (200 & 400 mg/kg body weight) leaves in alloxan-induced diabetic rats, showed significant (P<0.01) reduction in the blood glucose concentration in dose dependent manner.

   • According to Jawonisi OI (2015)

     Excerpt The antidiabetic activity was evaluated using adult male albino rats induced with diabetes using 150 mg/kg alloxan monohydrate. Diabetes mellitus is a metabolic disorder with high prevalence worldwide and is a major medical concern.

   • According to Venkatachalam T (2011)

     Excerpt To evaluate the hypoglycemic activity of methanolic extract of lantana camara Linn fruits in normal & streptozotocin induced diabetic rats. Material & methods: Methanolic extract of LC fruits were orally tested at the dose of 100 & 200 mg/kg for hypoglycemic activity for normal & streptozotocin induced diabetic rats.

2. 2

   Type II diabetes mellitus

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Jawonisi OI (2015)

     Excerpt The antidiabetic activity was evaluated using adult male albino rats induced with diabetes using 150 mg/kg alloxan monohydrate. Diabetes mellitus is a metabolic disorder with high prevalence worldwide and is a major medical concern.

   • According to Venkatachalam T (2011)

     Excerpt To evaluate the hypoglycemic activity of methanolic extract of lantana camara Linn fruits in normal & streptozotocin induced diabetic rats. Material & methods: Methanolic extract of LC fruits were orally tested at the dose of 100 & 200 mg/kg for hypoglycemic activity for normal & streptozotocin induced diabetic rats.

   • According to Balti T (2022)

     Excerpt Our data mainly showed that Lc leaf extract exerted glucose lowering activity that could be exploited in the struggle against diabetes, but also harbored toxic side effects within pancreas that was in fine corrected upon GSSE treatment. Glycemia was evaluated each week & liver glycogen & insulinemia as well as pancreas oxidative stress & energy fueling disturbances measured at the end of the treatment.

   • According to Ganesh T (2010)

     Excerpt Present study demonstrated that methanol extract of LC leaves exhibit promising anti-hyperglycemic activity against alloxan-induced diabetic rats. Oral administration of the methanol extract of LC (200 & 400 mg/kg body weight) leaves in alloxan-induced diabetic rats, showed significant (P<0.01) reduction in the blood glucose concentration in dose dependent manner.

   • According to Sen S (2010)

     Excerpt Present study demonstrated that methanol extract of LC leaves exhibit promising anti-hyperglycemic activity against alloxan-induced diabetic rats. Oral administration of the methanol extract of LC (200 & 400 mg/kg body weight) leaves in alloxan-induced diabetic rats, showed significant (P<0.01) reduction in the blood glucose concentration in dose dependent manner.

3. 3

   Cancer: adjuvant treatment for hormone-dependent breast cancer

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Dawood AS (2021)

     Excerpt Lantadene A (LA) which is one of the major pentacyclic triterpenoids in Lantana camara leaves was reported to exhibit anticancer property. However, the detail mechanism of LA inhibition against prostate cancer cells is still remained unknown.

   • According to Pal A (2024)

     Excerpt Lantana camara has been reported to cure a number of ailments, with few studies showing its cytotoxic effects on breast cancer cells. The present study investigated the effect of ethanolic extract of LC leaves on the triple negative breast cancer cell line, MDA-MB-231.

   • According to Pal A (2023)

     Excerpt Lantana camara has been reported to cure a number of ailments, with few studies showing its cytotoxic effect on breast cancer cell lines. The present study investigated the effect of ethanolic extract of LC leaves on the triple negative breast cancer cell line, MDA-MB-231.

   • According to Dhatwalia B (2024)

     Excerpt :The purpose of the current study was to examine the anti-cancer & antioxidant properties of an ethanolic extract of Lantana camara (LC) leaves against MCF-7. Conclusion:

   • Excerpt According to the current study, LC leaf extract significantly possesses antioxidant & anti-cancer properties against breast cancer cell line.

   • According to Kumar S (2022)

     Excerpt IC50 value calculated using linear regression analysis.This study shows bioactive compound present that LC may be useful as a drug against Breast cancer. In present study we are exploring the therapeutic uses of constitute of Lantana Camara’s leaves.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.