Lippia alba (Brizé) : medicinal properties in alcoholic extraction

Lippia alba (Brizé, Twa-tas, broken, Three-cups, brisée, Trois-tasses) — family Verbénacées.

Scientific synonyms : Lantana alba-Mill, Lippia geminata-HBK, L germinata var. microphylla-Griseb, L lantanoides-Coult.

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 10 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 43 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Pain, hyperalgesia

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Viana G.S.B (1998)

     Excerpt Viana G.S.B et al, Analgesic & antiinflammatory effects of two chemotypes of Lippia alba: a comparative study.

   • According to Haldar S (2012)

     Excerpt Conclusion The results suggest that the extracts of L alba possess antinociceptive & anti–inflammatory activities & its help to authenticates the use of the plant in the traditional treatment of ailments associated with pain & inflammation. To evaluate antinociceptive and anti–inflammatory activities of Lippia alba (Mill.) N.E.

   • According to Carmona F (2013)

     Excerpt We aimed to investigate the effects of Lippia alba (Mill.) N. Results: We observed a significant decrease on HIT-6 total score, as well as MIDAS number of missed days, number of headache days, & pain intensity.

   • According to Pereira-de-Morais L (2019)

     Excerpt The species Lippia Alba (Mill.) N. Popularly known as "erva-cidreira", it is widely used because of its sedative, carminative and analgesic properties.

   • According to Sousa DG (2015)

     Excerpt Lippia Alba is empirically used for infusions, teas, macerates, and hydroalcoholic extracts because of its antispasmodic, analgesic, sedative, and anxiolytic effects. Alba essential oil and possesses analgesic, anxiolytic, anticonvulsant, and sedative effects.

2. 2

   Cancer: chemoprevention

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Da S Gomide (2013)

     Excerpt Thus, this study aimed to evaluate in vitro cytotoxic effect of the essential oils extracted from five Lippia species against tumor cell lines. The results indicated that mouse colon carcinoma CT26.WT cell line viability was significantly reduced showing an IC50 of 19.05, 30.20 and 36.30 μg/ml when treated with the essential oils of L.

3. 3

   Osteoarthritis, arthritis, rheumatism, oedema

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Haldar S (2012)

     Excerpt Conclusion The results suggest that the extracts of L alba possess antinociceptive & anti–inflammatory activities & its help to authenticates the use of the plant in the traditional treatment of ailments associated with pain & inflammation. To evaluate antinociceptive and anti–inflammatory activities of Lippia alba (Mill.) N.E.

   • According to Viana G.S.B (1998)

     Excerpt Viana G.S.B et al, Analgesic & antiinflammatory effects of two chemotypes of Lippia alba: a comparative study.

   • According to Quintero Ruiz N (2017)

     Excerpt The anti-genotoxicity against ultraviolet radiation (UV)-induced DNA damage of essential oils (EO) from Lippia species was studied using SOS Chromotest. origanoides, thymol-RC > Lippia alba, citral-RC ≈ Lippia citriodora, citral-RC ≈ Lippia micromera, thymol-RC > L.

   • According to DUARTE MCT (2005)

     Excerpt Essential oils from 13 plants showed anti-Candida activity, including Aloysia triphylla, Anthemis nobilis, Cymbopogon martini, Cymbopogon winterianus, Cyperus articulatus, Cyperus rotundus, Lippia Alba, Mentha arvensis, Mikania glomerata, Mentha Piperata, Mentha sp., Stachys byzantina, and Solidago chilensis. Essential oils and ethanolic extracts from the leaves and/or roots of 35 medicinal plants commonly used in Brazil were screened for anti-Candida albicans activity.

   • According to Moreno ÉM (2018)

     Excerpt Alba EOs, produced under diverse environmental conditions, were extracted by microwave assisted hydrodistillation, and chemically characterized using gas chromatography coupled mass spectrometry. Alba EOs displayed significant differences in their chemical composition and trypanocidal performance (p = 0.0001).

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.