Lippia graveolens (Mexican oregano) : medicinal properties in alcoholic extraction

Lippia graveolens (Mexican oregano, Origan du Mexique) — family Verbenacées.

Scientific synonyms : ---.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 4 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 17 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for lung cancer

   Plant part used: stem.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to FRIAS-CEPEDA MA (2021)

     Excerpt The aim of this work was to evaluate the cytotoxic effect of ethanolic extracts obtained from free-oil leaves (L9) & stem (S15), against lung cancer cell line SK-LU-1, through tetrazolium salt (MTT) assay. The ethanolic extracts of LG have excellent cytotoxic activity, & have a wide possibility of use in lung cancer treatment.

   • According to Amador S (2020)

     Excerpt Lippia graveolens is a plant used for a variety of medicinal purposes & as a seasoning. The flavonol 4 inhibited moderately the proliferation of the U251 (glioblastoma) & SK-LU-1 (lung adenocarcinoma) cell lines.

   • According to Criollo-Mendoza MS (2022)

     Excerpt Oregano infusions have traditionally been used to treat some diseases related to inflammation & cancer; also, some species have shown antiproliferative activity on cancer cell lines, for example, colon and liver, & this has been attributed to its phytochemical profile, mainly its phenolic compound. Furthermore, the cytotoxicity of the extracts was evaluated in vitro on a non-cancer cell line of fibroblast NIH3T3 & the antiproliferative potential on the breast cancer cell lines MDA-MB-231 & MCF-7.

2. 2

   Oxidative stress

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Cortés-Chitala MC (2021)

     Excerpt Chromatographic identification & quantification of phenolic compounds & evaluation of their antioxidant activity were important tools to obtain a better characterization of this spice.

   • According to CACERES A (2012)

     Excerpt pepo, Erythrina berteroana, Fernaldia Pandurata, Gliricidia sepium, Lippia graveolens, Litsea guatemalensis, Manilkara sapota, Neurolaena lobata, Ocimum micranthum, Phlebodium pseudoaureum, Pimenta dioica, Piper auritum, Smilax domingensis, Solanum nigrescens, Spondias mombin, Tagetes lucida & Yucca éléphantipes). Antioxidant activity was evaluated by macro- & micro-quantification of total phenolics by Folin-Ciocalteu, total antioxidant capacity using DPPH, & Iron reducing power.

   • According to Criollo-Mendoza MS (2022)

     Excerpt LG showed the highest antioxidant capacity & significantly inhibited the proliferation of MCF-7 & MDA-MB-231 cells at non-cytotoxic concentrations in normal cells, with a similar effect to that cisplatin in MDA-MB-231 cells. The extract was characterized by determining antioxidant activity, total phenols content, & identifying the profile of phenolic acids & flavonoids by chromatography UPLC-MS/MS.

3. 3

   Metabolic syndrome, obesity

   Plant part used: stem.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to FRIAS-CEPEDA MA (2022)

     Excerpt Ethanolic extract of Mexican oregano (Lippia graveolens) stem (Ext) had a favorable effect on biochemical markers in a murine model of MetS, induced by injection of monosodium glutamate (MSG). The aim of this work was to determine the effect of Mexican oregano ethanolic extract in metabolic syndrome in murine model.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.