Luffa cylindrica (Lyenn dishcloth) : medicinal properties in alcoholic extraction

Luffa cylindrica (Lyenn dishcloth, Liane dishcloth, Loofah, Lyenn tôchon, Liane torchon) — family Cucurbitacées.

Scientific synonyms : Bryonia cheirophylla Wall., Luffa acutangula var. subangulata (Miq.) Cogn, L aegyptiaca Mill., L insularum A.Gray, L leucosperma M.Roem, L pentandra Roxb., L petola Ser., L subangulata Miq., L sylvestris Roxb., Melothria touchanensis H.Lév., Momordica cylindrica Linn., M luffa Linn.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 15 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 110 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Paracetamol-induced liver disorders: cirrhosis, hepatitis, fatty liver; normalisation of serum parameters: ALT, AST, ALT; total bilirubin, hypercholesterolaemia, albuminuria, etc.

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Pal KR (2011)

     Excerpt The present study was made to evaluate the hepatoprotective effect of alcoholic & aqueous extracts of fruits of LC in paracetamol induced hepatic injury in experimental animal rats. Hepatoprotective activity of LC was studied by estimating the serum levels of alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP), direct & total bilirubin, cholesterol, triglycerides, total proteins & albumin.

   • According to Balakrishnan N (2011)

     Excerpt Balakrishnan N et al, Protective Effect of Luffa cylindrica L. Fruit in Paracetamol Induced Hepatotoxicity in Rats Inter J of Pharmaceut & Biol Archives 2011; 2(6):1761-4-.

   • According to Sharma NK (2014)

     Excerpt The extract showed a dose-dependent reduction of paracetamol induced elevated serum levels of enzyme activities indicating the extract could preserve the normal functional status of the liver. The study was conducted by estimating serum enzyme activities of serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT)), alkaline phosphatase (ALP) & bilirubin & by estimation of some serum antioxidant enzymes.

   • According to Ankul-Singh S (2024)

     Excerpt Treatment-related adverse events, such as alterations in hematology & serum biochemistry parameters and the histology of the liver were sporadic in the high-dose rats but within the reference range. The loofah/sponge gourd Luffa cylindrica (L.), a member of the Cucurbitaceae family, is one of the neglected medicinal plants.

   • According to Abd-el Salam IM (2019)

     Excerpt Luffa cylindrica (L.) M. Aim of the study: To evaluate the anticancer activity of the hot water extract of the whole plant of LC using circulating tumor cells & cancer stem cells isolated from the peripheral blood of hepatocellular carcinoma patients in vitro.

2. 2

   Fungal infection: Aspergillus niger, Aspergillus fumigatus, Candida albicans

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to SASHIKALA DEVI G (2009)

     Excerpt Ethanolic extract of LC were tested for antibacterial & antifungal efficacy against Gram positive & Gram-negative bacteria & Aspergillus fumigates, Aspergillus niger & Candida albicans organism. To investigate the antibacterial & antifungal activities of Ethanolic extract of Luffa cylindrica (Linn).

   • According to Muthumani P (2010)

     Excerpt To find out the pytochemical constitutents in the seeds of Luffa cylindrica and determine their anti-inflammatory, Bronchodilator & Antimicrobial activity.The fruit of Luffa cylindrica collected from the village, Othakadai near Madurai, Tamilnadu, south India were dried & the seeds were separated from the fruit & extracted with petroleum ether, benzene, chloroform & alcohol. Anti microbial activity was effective against S.aureus & Candida albicans.

   • According to Velmurugan V (2011)

     Excerpt The alcoholic & aqueous extracts of Luffa cylindrica Linn. The alcoholic extract has produced significant analgesic & antimicrobial activities.

   • According to Indumathy R (2011)

     Excerpt In this present investigation was to evaluate the antimicrobial activity of pet ether & chloroform extract of whole plant of Luffa cylindrica (Linn) by in-vitro method in agar plate against ten bacterial and four fungal species. The results of the above study clearly indicated that the chloroform extract of whole plant of LC was found significant antibacterial & antifungal activity which might be helpful in preventing the progress of various diseases & can be used in alternative system of medicine.

   • According to Onegbule FA (2018)

     Excerpt In the antimicrobial evaluation, the ethanol & ethyl acetate extracts showed moderate antibacterial activity against Staphylococcus aureus, Salmonella typhi, & Bacillus subtilis. Luffa cylindrica has been used traditionally in the treatment & management of several disease conditions.

3. 3

   Bacterial infection: Staphylococcus aureus, Salmonella typhi, & Bacillus subtilis

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Onegbule FA (2018)

     Excerpt In the antimicrobial evaluation, the ethanol & ethyl acetate extracts showed moderate antibacterial activity against Staphylococcus aureus, Salmonella typhi, & Bacillus subtilis. Luffa cylindrica has been used traditionally in the treatment & management of several disease conditions.

   • According to SASHIKALA DEVI G (2009)

     Excerpt To investigate the antibacterial & antifungal activities of Ethanolic extract of Luffa cylindrica (Linn). Ethanolic extract of LC were tested for antibacterial & antifungal efficacy against Gram positive & Gram-negative bacteria & Aspergillus fumigates, Aspergillus niger & Candida albicans organism.

   • According to Indumathy R (2011)

     Excerpt In this present investigation was to evaluate the antimicrobial activity of pet ether & chloroform extract of whole plant of Luffa cylindrica (Linn) by in-vitro method in agar plate against ten bacterial and four fungal species. The results of the above study clearly indicated that the chloroform extract of whole plant of LC was found significant antibacterial & antifungal activity which might be helpful in preventing the progress of various diseases & can be used in alternative system of medicine.

   • According to Muthumani P (2010)

     Excerpt To find out the pytochemical constitutents in the seeds of Luffa cylindrica and determine their anti-inflammatory, Bronchodilator & Antimicrobial activity.The fruit of Luffa cylindrica collected from the village, Othakadai near Madurai, Tamilnadu, south India were dried & the seeds were separated from the fruit & extracted with petroleum ether, benzene, chloroform & alcohol. Cu-2 & Cu-4 have significant antibacterial & antifungal activity.

   • According to Israt Jahan Bulbul (2010)

     Excerpt On the basis of results obtained, it is suggested that both LUCY & LUAC leaves extracts may be a potential source of natural antioxidants, antimicrobial compounds & anticancer agents to be used in the treatment of various oxidative disorders, infectious diseases caused by resistant microorganisms and cancer, respectively. The purpose of the present study was to investigate the antioxidant, antibacterial & cytotoxic activities of the n-hexane, chloroform & ethyl acetate extracts of leaves of LUCY & LUAC.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.