Lycoserpicon esculentum (Tonmat) : medicinal properties in alcoholic extraction

Lycoserpicon esculentum (Tonmat, Tonmadôz, Tomato, Tomadose, Tomate) — family Solanacées.

Scientific synonyms : Lycopersicon esculentum var. cerasiforme, L. esculentum var. cerasiforme (Dunal) A. Gray, Solanum lycopersicum var. cerasiforme-(Dunal)- D.M.Spooner & al.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 17 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 128 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to WAGHAMODE N (2024)

     Excerpt This study investigates the physicochemical attributes & phytochemical profile of SL alongside its pharmacological activities, particularly focusing on antidiabetic potential. Additionally, in vitro assays demonstrated significant alpha-glucosidase & DPP-4 inhibitory activities, indicating the potential of SL extracts as antidiabetic agents.

2. 2

   Cancer: adjuvant treatment for colorectal carcinoma and melanoma

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Saturnino C (2013)

     Excerpt Saturnino C et al, Antiproliferative Activity of Lycopersicon esculentum Leaves (Var. Paul Robenson): Preliminary Study, Food & Nut Sci, 2013, 4, 632-5-Among plants, the L esculentum is the most important for its beneficial effects on health.

   • According to Nguenang GS (2020)

     Excerpt Nguenang GS et al, Acute & subacute toxicity profiles of the methanol extract of Lycopersicon esculentum L. leaves (tomato), a botanical with promising in vitro anticancer potential.

   • According to Freudenheim JL (1996)

     Excerpt J Nat Cancer Inst, 88, 340-8, 1996- Purpose: We conducted a case—control study of diet, including the intake of non-food suppléments, and premenopausal breast cancer risk. They consisted of premenopausal women 40 years of age or older who were diagnosed with breast cancer from November 1986 through April 1991.

   • According to Freudenheim JL (1996)

     Excerpt Freudenheim JL et al, pre-menopausal breast cancer risk and intake of vegetable, fruits and related nutrients.

   • According to Chauhan M (2023)

     Excerpt (amla), & Lycopersicon esculentum M (tomatoes) are traditionally consumed functional foods that contain a high concentration of antioxidants, ascorbic acid, polyphenols, & numerous phytochemicals. The LS extract was tested in the MKN-45 human gastric cancer cell line to demonstrate its effective antioxidant potential & cytotoxicity.

3. 3

   Fungal infection: oropharyngeal candidiasis in an HIV-positive patient: Candida albicans, C. guilliermondii, C. lusitaniae

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Mladenović J (2015)

     Excerpt The objective of this study was to evaluate the cytotoxicity, antimicrobial & antioxidant activities of extracts of Daucus carota L., Lycopersicon esculentum Mill. The test extracts showed strong to moderate antimicrobial activity (19.53 - 312.50 mu g/mL).

   • According to Baissac Y (2004)

     Excerpt L'activité antifongique du tomatoside spirostanique B a également été évaluée sur d'autres espèces de Candida (C. Le tomatoside A, (25S)-5α-furostane-3β,-22α,-26-triol3-O-[O-β-D-glucopyranosyl(1 → 2)-β-D-gluco-pyranosyl(1 → 4)-β-D-galacto-pyranoside]26-O-β-D-gluco-pyranoside, principale saponine stéroïdique de la graine de tomate (Lycopersicon esculentum Mill), a été isolé à partir d'un extrait éthanolique de graines: L'hydrolyse enzymatique du tomatoside A par de la β-glucosidase libère le tomatoside B: (25S)-5α-spirostane-3β-ol 3-O-β-D-gluco-pyranosyl(1 → 2)-β-D-glucopyranosyl (1 → 4)-β-D-galacto pyranoside.

   • According to Ijato J (2011)

     Excerpt The reality of using these antifungal plants to control tomato rot serves as good option to chemical control.

   • According to MLADENOVIC J (2014)

     Excerpt The objective of this study was to evaluate cytotoxicity, antifungal & antioxidant activities of vegetable extracts (Lycopersicon esculentum M i l l. On the basis of the results obtained, extract was found to serve as a potential source of natural antioxidants and antimicrobial due to their marked activity.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.