Malva parviflora (Môv) : medicinal properties in alcoholic extraction

Malva parviflora (Môv, Mauve) — family Malvacées.

Scientific synonyms : Malva microcarpa- Desf.ex DC., M rotundifolia auct plur. non L..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 7 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 22 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II insulin-resistant diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Perez Gutierrez RM (2012)

     Excerpt We conclude that the hexane extract of MP leaves can efficiently inhibit insulin resistance, lipid abnormalities & oxidative stress, indicating that its therapeutic properties may be due to the interaction plant components soluble in the hexane extract, with any of the multiple targets involved in diabetes pathogenesis. As a result, we found that with the hexane extract the blood glucose level, serum biochemical parameters, hepatic enzymes, Thiobarbituric acid reactive substances, glycosylated hemoglobin, advanced glycation end products, & insulin level were restored in streptozotocin induced diabetic rats to nearly normal levels.

   • According to Perez-Gutierrez RM (2017)

     Excerpt The results suggest that 1 has hypolipidemic & hypoglycemic, anti-inflammatory, activities, improve insulin resistance & hepatic enzymes in streptozotocin-induced diabetic mice. The hypolipidemic & hypoglycemic activities of 1 was analyzed in in streptozotocin (STZ)-nicotinamide-induced type 2 diabetes in mice (MD) & type 1 diabetes in streptozotocin-induced diabetic mice (SD).

   • According to Mostapha MD (2022)

     Excerpt The extract & its nano-formulation have shown antidiabetic properties when tested on diabetic rats as they improved all the biochemical parameters; decreased glucose level in serum, increased insulin production, marked improvement in lipid profile, liver & kidney functions, & that was more proved with the histopathological examinations. Conclusively, MP extract & its nano-formulation could attenuate or effectively help in controlling diabetes through its therapeutic properties exhibited by the action of the plant antioxidant components.

   • According to Medrano-Jimenez E (2019)

     Excerpt Malva parviflora is a plant well known for its anti-inflammatory properties. Therefore, MP phytochemicals represent an alternative to prevent cognitive impairment associated with a metabolic disorder as well as an effective prophylactic candidate for AD progression.

2. 2

   Bacterial infection: Staphylococcus aureus, Klebsiella pneumoniae and Escherichia coli

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ododo MM (2016)

     Excerpt The chloroform extract showed antibacterial activity against Staphylococcus aureus & Escherichia coli, whereas the ethanolic extract showed antibacterial activity against only S. The powder of root bark of Malva parviflora (Malvaceae) was successively extracted with petroleum ether (b.p.

   • According to Shale TL (2005)

     Excerpt Malva parviflora leaves and roots were collected from five sites within the Qacha's Nek District in Lesotho. Hexane, methanol & water extracts were made from the plant material& tested for antibacterial & anti-inflammatory activity using the disc diffusion & cyclooxygenase-1 (Cox-1) bioassays, respectively.

   • According to Al-Otibi F (2021)

     Excerpt Cheese weed mallow (Malva parviflora L.) was used to biosynthesize silver nanoparticles. Finally, in vitro antifungal assay was done to assess the potential of biosynthesized silver nanoparticles & crude leaf extract of MP for inhibiting the mycelial growth of phytopathogenic fungi.

   • According to Abozed M (2018)

     Excerpt Antibiofilm effect was evaluated for Staphylococcus aureus, Klebsiella pneumonia & Escherichia coli using 96 wells technique. The purpose of this study was to investigate the efficacy of leaves extract of Malva parviflora as antibiofilm against different pathogens.

   • According to Mostapha MD (2022)

     Excerpt The antifungal activity of the extract was evident, especially with Fusarium culmorum & aspergillus flavus. MP bioactivity was evaluated by both antioxidant & antimicrobial assays.

3. 3

   Oxidative stress

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Perez Gutierrez RM (2012)

     Excerpt We conclude that the hexane extract of MP leaves can efficiently inhibit insulin resistance, lipid abnormalities & oxidative stress, indicating that its therapeutic properties may be due to the interaction plant components soluble in the hexane extract, with any of the multiple targets involved in diabetes pathogenesis. Malva parviflora (MP), known in Mexico by the name of "quesitos" or "malva", is popular due to its culinary & medicinal properties.

   • According to Bouriche H (2011)

     Excerpt Discussion & conclusion: These findings demonstrate that MP leaf extracts possess anti-inflammatory & antioxidant activities & thus have great potential as an interesting source for natural health products. The antioxidant effects were evaluated using the 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical assay & the measurement of the metal-chelating activity.

   • According to Afolayan AJ (2008)

     Excerpt The free radical scavenging activity of the methanolic extract of Malva parviflora L. Total phenolic, flavonoid & proanthocyanidin contents were also determined to assess their effects on the antioxidant activity of the extract.

   • According to Farhan H (2012)

     Excerpt In the present work the total phenolic & total flavonoid contents from the extracts of crude leaves & stems of Malva parviflora grown in Lebanon have been determined using the Folin-Ciocalteu reagent & aluminum chloride methods. On the other hand, the antioxidant ability of these extract has been estimated using three different methods 1,1-diphenyl-2-picrylhydrazyl (DPPH), hydrogen peroxide (H2O2) & chelating of ferrous ions tests.

   • According to Abd-El-Salem EA (2019)

     Excerpt Box-Behnken Design (BBD) was used to optimize the extraction conditions of polyphenols from Malva (Malva parviflora L.) leaves.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.