Mangifera indica (Mango) : medicinal properties in alcoholic extraction

Mangifera indica (Mango, mangue) — family Anacardiacées.

Scientific synonyms : Mangifera austroyunnanenis-H..

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 33 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 141 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment of hormone-dependent uterine, liver and breast cancer; chemoprevention

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to QUINTANA SE (2021)

     Excerpt These phytochemicals exhibit antioxidant, antimicrobial, anti-inflammatory, & anticancer activity, & depending on the source (bark, leaves, seeds, flowers, or peel) & extraction method there will be differences in the structure & bioactivity. Mango (Mangifera indica) has been recognized as a rich source of bioactive compounds with potential pharmaceutical & nutraceutical applications & has attracted increasing interest from research.

   • According to MORENO DA (2006)

     Excerpt This study assesses the effects of mango tree (Mangifera indica L.) extracts (stem bark - MSB & leaves - ML) on lipases (pancreatic lipase, lipoprotein lipase & hormone-sensitive lipase). In addition, MSB&d ML increased fécal fat excretion &d reduced serum glucose & insulin levels and downregulated some obesity-related genes(LPL, hormone-sensitive lipase, fatty acid synthase, resistin) in liver and epididymal fat.

   • According to Nadella SK (2016)

     Excerpt This experimental study was undertaken to see the hepatoprotective activity of ethanol extract of Mangifera-indica dried leaves against CCl4 induced acute liver damage on albino rats. These results suggest that this MI leaf Extract may have the potential therapeutic value in the treatment of CCl4 induced hepatic damage & some liver diseases.

   • According to SODJINOU BD (2024)

     Excerpt Talinum triangulare & Mangifera indica leaves could have prebiotic properties because they stimulated the production of short-chain fatty acids that keep animals healthy,. However, broilers fed with Talinum triangulare & Mangifera indica powders showed a lower mortality rate, compared to the negative & positive control treatments.

   • According to Prabhakar P (2022)

     Excerpt Of the many fruiting trees indigenous to India, Mango (Mangifera indica), Black plum (Eugenia jambolana or Syzygium jambolana), Indian gooseberry (Emblica officinalis or Phyllanthus emblica), kokum (Garcinia indica or Brindonia indica), stone apple or bael (Aegle marmelos), Jackfruit (Artocarpus heterophyllus), Karaunda (Carissa carandas) & Phalsa (Grewia asiatica), Monkey Jackfruit (Artocarpus lakoocha) & Elephant apple (Dillenia indica) have been shown to be beneficial in preventing cancer & in the treatment of cancer in validated preclinical models of study. Indigenous fruits and their bioactive compounds with beneficial effects like antioxidant, antiproliferative, & immunomodulatory are shown to be useful in preventing the incidence of cancer.

2. 2

   Type II diabetes mellitus

   Plant part used: Sheet. Mentioned synergistic association: association synergique avec TRIDAX PROCUMBENS-L (Plante entière).

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Petchi RR (2014)

     Excerpt Glycosmis pentaphylla, Tridax procumbens & Mangifera indica are well-known plants available throughout India and they are commonly used for the treatment of various diseases including diabetes mellitus. The oral antidiabetic activity of the polyherbal formulation (250 & 500 mg/kg) was screened against streptozotocin (50 mg/kg; i.p.) + nicotinamide (120 mg/kg; i.p.) induced diabetes mellitus in rats.

   • According to Kemasari P (2011)

     Excerpt Present investigation was undertaken to evaluate antihyperglycaemic, activity of ethanolic extract of Mangifera indica leaves in alloxan induced diabetic rats. Administration of M indica to diabetic rats reduced the effect of alloxan & increased the levels of above parameters.

   • According to Venkatalakshmi P (2011)

     Excerpt Present investigation was undertaken to evaluate antihyperlipidemic and antioxidant activities of ethanolic extract of Mangifera indica leaves in alloxan induced hyperlipidemic rats. Treatment with Mangifera indica extract produced decrease in alloxan induced lipid levels.

   • According to Dinesh Kumar B (2010)

     Excerpt Ten common plants in IIT Kharagpur 1 Block namely, Acalypha indica, Allium cepa, Allium sativum, Azadirachta indica, Musa sapientum, Mangifera indica, Murraya, Ocimum sanctum, Phyllanthus amarus & Tinospora cordifolia were tested for their alpha amylase inhibitory activities to establish Anti-diabetic potentials. The results showing that M indica, A indica & M koenigii might be effective in lowering post prandial hyperglycemia.

   • According to Mirza B (2021)

     Excerpt MI has been shown to exhibit various biological & pharmacological activities, such as antioxidant, anti-inflammatory, immunomodulatory, antimicrobial, antidiabetic, antiobesity, & anticancer effects.

3. 3

   Cirrhosis, hepatitis, fatty liver disease

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Nadella SK (2016)

     Excerpt This experimental study was undertaken to see the hepatoprotective activity of ethanol extract of Mangifera-indica dried leaves against CCl4 induced acute liver damage on albino rats. These results suggest that this MI leaf Extract may have the potential therapeutic value in the treatment of CCl4 induced hepatic damage & some liver diseases.

   • According to MORENO DA (2006)

     Excerpt This study assesses the effects of mango tree (Mangifera indica L.) extracts (stem bark - MSB & leaves - ML) on lipases (pancreatic lipase, lipoprotein lipase & hormone-sensitive lipase). In addition, MSB&d ML increased fécal fat excretion &d reduced serum glucose & insulin levels and downregulated some obesity-related genes(LPL, hormone-sensitive lipase, fatty acid synthase, resistin) in liver and epididymal fat.

   • According to SODJINOU BD (2024)

     Excerpt Talinum triangulare & Mangifera indica leaves could have prebiotic properties because they stimulated the production of short-chain fatty acids that keep animals healthy,. However, broilers fed with Talinum triangulare & Mangifera indica powders showed a lower mortality rate, compared to the negative & positive control treatments.

   • According to QUINTANA SE (2021)

     Excerpt Mango (Mangifera indica) has been recognized as a rich source of bioactive compounds with potential pharmaceutical & nutraceutical applications & has attracted increasing interest from research.

   • According to GONSALVES-DUARTE L (2025)

     Excerpt The edible & nonedible parts of the mango (Mangifera indica L.) contain vitamins, phytocompounds, fiber, & fatty acids.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.