Martynua annua (Grif-djab) : medicinal properties in alcoholic extraction

Martynua annua (Grif-djab, Krôk-sépan, Devil’s Claw, Snake Fang, Griffe-à-diable, Croc-à-serpent) — family Martyniacées.

Scientific synonyms : Martynia diandra-Gloxin.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 13 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 54 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment of breast, lung, oral squamous cell and uterine carcinomas, and leukaemia

   Plant part used: Root.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Gupta R (2020)

     Excerpt Further evaluation of pharmacological activities & cell line studies of MA may prove useful in treatment of cancer & heart diseases. The present study was intended to research the antioxidant potential of aqueous extract, Hydroalcoholic extract & Alcoholic extract from Martynia annua root.

   • According to Gupta RK (2021)

     Excerpt Results: Aqueous & ethanolic extract of MA root had shown high anticancer activity with GI50 value 11.3μg/ml & 20.4μg/ml respectively on human leukemia cell line K-562 but for human breast cancer cell line MCF-7, human lung cancer cell line A-549, human squamous cell carcinoma SCC-40 & human cervical cancer cell line SiHa the extracts showed activity in more than 80μg/ml. Settings & Design: In the experiment, lung cancer cell lines (cancer cell lines (K562), oral cancer cell lines (SCC-40), breast cancer cell lines cancer cell lines (SiHa) were studied on the extracts.

   • According to Gupta R (2021)

     Excerpt Root paste of MA is used in folk medicine to treat cancer & rheumatism. This study reports on standardization of Martina annua root.

   • According to Rameshroo K (2014)

     Excerpt Natural antioxidants may help the body to protect itself from various types of oxidative damage which are linked to diseases such as cancer, diabetes, cardiovascular disorders & aging. Martynia annua belonging to Martynaceae family are found to be a rich source of substances of phytochemical interest.

   • According to Kaushik S (2021)

     Excerpt Martynia annua has been used in Indian traditional therapies for the treatment of epilepsy, many types of inflammations, respiratory infection, sore throat & wound. In vivo anti-arthritic of fruit extract was performed on Complete Freund’s adjuvant (CFA) induced arthritis in rats.

2. 2

   Osteoarthritis, arthritis, rheumatism, oedema

   Plant part used: Aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Pandey P (2021)

     Excerpt Aim of the present study was to investigate preliminary evaluation of hydrogel formulation of methanol fraction of Martynia annua for anti-inflammatory activity using different types of animal models. Prepared hydrogel was characterized for optimization & screened for anti-inflammatory activity using Xylene induced ear edema & Croton oil-induced ear edema in mice.

   • According to Dinghra (2020)

     Excerpt To carryout phyto-chemical screening in conjunction with in vitro antimicrobial & anti-inflammatory potential of Martynia annua. The in vitro antimicrobial activity of various extracts was evaluated by using agar plate diffusion microbiological assay, while inhibition of protein denaturation assay was used for evaluation of anti-inflammatory potential.

   • According to Akanksha B (2021)

     Excerpt The entire plant contains a substantial amount of biologically active constituents that have been reported to show potentially significant pharmacological activities including anti-inflammatory, antibacterial & anticonvulsant. Martynia annua L or Martynia Diandra Gloxin is a herbaceous plant belonging to the family Martyniaceae.

   • According to Das N (2021)

     Excerpt The entire plant contains a substantial amount of biologically active constituents that have been reported to show potentially significant pharmacological activities including anti-inflammatory, antibacterial & anticonvulsant. The herb is cultivated to be used as an ornamental & a medicinal plant.

   • According to Muazzam Saba (2018)

     Excerpt Previous studies have shown that preparations from the plant have antiseptic, anti-inflammatory, & antiepileptic effects in vitro, but the biochemical composition & active compounds responsible for health benefits remain unknown. The aim of this study was to take extracts from different parts of the MA plant &, using targeted & untargeted metabolite profiling & quantitation, provide a comprehensive secondary metabolite profile to identify potential biotherapeutic metabolites.

3. 3

   Arthritis, osteoarthritis, rheumatism

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Muazzam Saba (2018)

     Excerpt Previous studies have shown that preparations from the plant have antiseptic, anti-inflammatory, & antiepileptic effects in vitro, but the biochemical composition & active compounds responsible for health benefits remain unknown. Martynia annua is an indigenous plant found endemic in the Indian subcontinent where it is commonly used for self-treatment of a variety of ailments & diseases.

   • According to Dinghra (2020)

     Excerpt To carryout phyto-chemical screening in conjunction with in vitro antimicrobial & anti-inflammatory potential of Martynia annua. The in vitro antimicrobial activity of various extracts was evaluated by using agar plate diffusion microbiological assay, while inhibition of protein denaturation assay was used for evaluation of anti-inflammatory potential.

   • According to Pandey P (2021)

     Excerpt Aim of the present study was to investigate preliminary evaluation of hydrogel formulation of methanol fraction of Martynia annua for anti-inflammatory activity using different types of animal models. Prepared hydrogel was characterized for optimization & screened for anti-inflammatory activity using Xylene induced ear edema & Croton oil-induced ear edema in mice.

   • According to Akanksha B (2021)

     Excerpt The entire plant contains a substantial amount of biologically active constituents that have been reported to show potentially significant pharmacological activities including anti-inflammatory, antibacterial & anticonvulsant. Martynia annua L or Martynia Diandra Gloxin is a herbaceous plant belonging to the family Martyniaceae.

   • According to Arshad Z (2018)

     Excerpt annua have been used to cure epilepsy, inflammation, tuberculosis, skin infections etc. Martynia annua (cat’s claw, bichu) is part of Martyniaceae family.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.