Mentha pulegium (Lanmant) : medicinal properties in alcoholic extraction

Mentha pulegium (Lanmant, Mint Warbler, Menthe Pouillot) — family Lamiacées.

Scientific synonyms : Mentha daghestanica Boriss. Mentha pulegium var. villosa Benth., M tomentella H. & Link, M tomentosa Sm., M daghestanica B. M exigua L., M gibraltarica Willd., M pulegium var. exigua (L.)-N, M pulegium var. gibraltarica (Willd.)-Batt., Pulegium var. pulegioides (Dumort.), P aromaticum Gray, P benearnense G, P erectum Mill., P tomentellum (H & L), P vasconicum Gand., P vulgare Mill..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 3 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 74 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Termination of pregnancy

   Plant part used: Aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to El-Gazar A (2022)

     Excerpt Administration of MP extract/fractions, for three days starting from day 15th of gestation, affected fetal development by disrupting the uterine & placental tissues, or even caused pregnancy termination. (MP, Lamiaceae) is a common insect repellent, & the present work validates its abortifacient capacity, targeting morphological anomalies, biological, & behavioral consequences, compared to Misoprostol.

   • According to COFFE PN (2024)

     Excerpt Historically, Mentha pulegium has served for contraceptive & abortive purposes. Conclusions: The observed anti-implantation activity & pre-implantation loss suggest the abortifacient properties of MPE.

   • According to EL-GAZAR A (2022)

     Excerpt Administration of MP extract/fractions, for three days starting from day 15th of gestation, affected fetal development by disrupting the uterine & placental tissues, or even caused pregnancy termination. (MP, Lamiaceae) is a common insect repellent, & the present work validates its abortifacient capacity, targeting morphological anomalies, biological, & behavioral consequences, compared to misoprostol.

2. 2

   Difficult labour: uterine atony, inadequate contractions, postpartum haemorrhage, induction of uterine contraction following obstetric surgery

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to COFFE PN (2024)

     Excerpt Historically, Mentha pulegium has served for contraceptive & abortive purposes. Results: Post-coital administration of MPE resulted in resorptive, pre-implantation loss, & anti-implantation activity.

   • According to Azadi S (2023)

     Excerpt Methods: In this study, the chemical composition of Mentha pulegium essential oil with five major compounds, including pulegone (68.11%), l-menthone (8.83%), limonene (2.90%), iso-pulegone (2.69%), & iso-menthone (1.48%) was first identified using GC-MS (Gas chromatography-Mass Spectrometry) analysis. Results: The results showed that cell viability was reduced by 90 & 45% after treatment with 300 μg/mL of the nanogel & nano-scaled emulsion.

   • According to Kelidari HR (2021)

     Excerpt In this study, ingredients of Mentha longifolia & Mentha pulegium essential oils were first identified by GC-MS analysis. After that, solid lipid nanoparticles containing each essential oil with particle sizes of 107 ± 9 (PDI 0.274) and 191 ± 8 (PDI 0.174) nm & zeta potential -7.10 and -4.81 mV were prepared.

   • According to El-Gazar A (2022)

     Excerpt These effects also entailed biochemical changes where they decreased progesterone & increased estradiol serum levels, modulated placental gene expressions of both MiR-(146a & 520), decreased uterine MMP-9, & up-regulated TIMP-1 protein expression, & empathized inflammatory responses (TNF-α, IL-1β). Administration of MP extract/fractions, for three days starting from day 15th of gestation, affected fetal development by disrupting the uterine & placental tissues, or even caused pregnancy termination.

   • According to Jafari-Sales, A (2019)

     Excerpt In this study, the antimicrobial effects of methanolic extract of Mentha pulegium against S. After collecting the plants, essential oil of aerial parts of the plant was done by distillation with water through the Clevenger apparatus.

3. 3

   Menopause, oestrogen deficiency

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to COFFE PN (2024)

     Excerpt Historically, Mentha pulegium has served for contraceptive & abortive purposes. A marked decline in serum progesterone levels & a significant reduction in serum estrogen & progesterone ratio was observed at 200 mg/kg MPE.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.