Mentha spicata (Lanmant kouwant) : medicinal properties in alcoholic extraction

Mentha spicata (Lanmant kouwant, Lanmant dous, Common mint, Sweet mint, Menthe courante, Menthe douce) — family Lamiacées.

Scientific synonyms : Mentha crispa -L, M crispata Schrad. Ex Willd., M glabra-Mill, M pudina Buch. -Ham. Ex Benth., M spicata var. viridis L., M viridis (L.) L..

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 9 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 103 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Hypertension in people with diabetes, cardiac hypertrophy

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Mushtaq A (2017)

     Excerpt Methodology: In this study aqueous ethanolic extracts of Mentha spicata (leaves), Plumeria alba (leaves) & Nymphaea alba (flowers & rhizomes) were evaluated individually in 200mg/kg & 400mg/kg doses against alloxan (130mg/kg i.p.) induced hyperglycemic rats. Any impairment in the functionality of insulin leads to long lasting metabolic disorder called diabetes mellitus which can be described as a group of disorders i.e., hyperlipidemia, cardiomyopathy, nephritis, fatty liver & weight loss.

   • According to Rakebizadeh M (2018)

     Excerpt Results of statistical analysis in relation to body weight of rats showed that there was a significant relationship between all groups at P<0.05 except for diabetic group & diabetic group by Mentha spicata Butanol extract as well as diabetic group by MS butanol extract & diabetic groups by MS butanol extract & zinc oxide nanoparticles. When applied as a supplement, zinc oxide nanoparticles & MS butanol extract can have anti-diabetic properties, curtailing blood glucose, revealing that nanoparticles can be used in the future as a treatment for diabetes.

   • According to Zare T (2012)

     Excerpt Zare T et al, The Effect of Hydroalcoholic Extracts of Mentha spicata on Blood Factors of Kidney & Liver Functions in Diabetic Male Wistar Rats J FUM S.ci 2012; 2 (3) :174-80-.

   • According to Farid O (2018)

     Excerpt Methods: In this work, the effect of Mentha spicata aerial part aqueous extract (A.P.A.E) at a dose of 20 mg/kg body weight on blood glucose levels has been demonstrated in normal & streptozotocin (STZ) diabetic rats. However, repeated oral administration of MS aqueous extract showed a significant blood glucose lowering effect (p<0.0001) in STZ diabetic rats.

   • According to Bayani M. (2017)

     Excerpt This study was conducted to evaluate the hypoglycemic, hypocholesterolemic & antioxidant properties of Mentha spicata (Labiateae) leaves aqueous extract (MSLA) in alloxan-induced diabetic rats.

2. 2

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Mushtaq A (2017)

     Excerpt Methodology: In this study aqueous ethanolic extracts of Mentha spicata (leaves), Plumeria alba (leaves) & Nymphaea alba (flowers & rhizomes) were evaluated individually in 200mg/kg & 400mg/kg doses against alloxan (130mg/kg i.p.) induced hyperglycemic rats. Any impairment in the functionality of insulin leads to long lasting metabolic disorder called diabetes mellitus which can be described as a group of disorders i.e., hyperlipidemia, cardiomyopathy, nephritis, fatty liver & weight loss.

   • According to Farid O (2018)

     Excerpt Methods: In this work, the effect of Mentha spicata aerial part aqueous extract (A.P.A.E) at a dose of 20 mg/kg body weight on blood glucose levels has been demonstrated in normal & streptozotocin (STZ) diabetic rats. The objective of this study was to evaluate the antidiabetic effect of this plant in the experimental diabetic state.

   • According to Bayani M. (2017)

     Excerpt This study was conducted to evaluate the hypoglycemic, hypocholesterolemic & antioxidant properties of Mentha spicata (Labiateae) leaves aqueous extract (MSLA) in alloxan-induced diabetic rats.

   • According to El-Menyiy N (2022)

     Excerpt Mentha spicata, also called Mentha viridis, is a medicinal plant of the Lamiaceae family characterized by its potency to synthesize & secret secondary metabolites, essentially EOS. Moreover, MS exhibited,

   • Excerpt according to some studies, promising antioxidant, antidiabetic, anti-inflammatory, & anticancer effects, which show its potential to be used as a source for identifying natural drugs against cellular oxidative stress & its related diseases.

   • According to Rakebizadeh M (2018)

     Excerpt Results of statistical analysis in relation to body weight of rats showed that there was a significant relationship between all groups at P<0.05 except for diabetic group & diabetic group by Mentha spicata Butanol extract as well as diabetic group by MS butanol extract & diabetic groups by MS butanol extract & zinc oxide nanoparticles. When applied as a supplement, zinc oxide nanoparticles & MS butanol extract can have anti-diabetic properties, curtailing blood glucose, revealing that nanoparticles can be used in the future as a treatment for diabetes.

3. 3

   Cancer: adjuvant treatment for prostate cancer

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Shireen F (2022)

     Excerpt Green silver nanoparticles (AgNPs) & crude ethanolic, methanolic, aqueous, & acetonic extracts from leaves of Agave americana, Mentha spicata, & Mangifera indica were scrutinized for possible antineoplastic & cytotoxic efficacy. MI- & MS-based AgNPs displayed moderate activity against PC-3 (prostate cancer cell line).

   • According to Arumugam P (n.d.)

     Excerpt Total antioxidant activity (TAA) & cytotoxic effect of four solvent fractions of ethanol extract of Mentha spicata L. Cytotoxic effect on human prostate cancer cell line (PC-3) was assessed by MTT assay.

   • According to Torres-Martínez Y (2019)

     Excerpt In this study, silver nanoparticles (NP) were synthesized by two methods: using an aqueous extract of Mentha spicata leaves & using citrate ions as stabilizing agent, & the cytotoxicity & anticancer activity of both NP were evaluated in vitro. spicata is an excellent alternative for the synthesis of silver NP.

   • According to El-Menyiy N (2022)

     Excerpt Mentha spicata, also called Mentha viridis, is a medicinal plant of the Lamiaceae family characterized by its potency to synthesize & secret secondary metabolites, essentially EOS. Moreover, MS exhibited,

   • Excerpt according to some studies, promising antioxidant, antidiabetic, anti-inflammatory, & anticancer effects, which show its potential to be used as a source for identifying natural drugs against cellular oxidative stress & its related diseases.

   • According to Rasti F (2022)

     Excerpt Rasti F et al, Antioxidative, anticancer, & antibacterial activities of a nanogel containing Mentha spicata L. Methods: In this study, the chemical composition of the Mentha spicata EO was first investigated using GC-MS analysis.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.