Microtea debilis (Maripérinn’) : medicinal properties in alcoholic extraction

Microtea debilis (Maripérinn’, Marie-Perrine) — family Phytolaccacées.

Scientific synonyms : Microtea debilis var. ovata Delile ex Moq. M debilis var. rhombifolia Moq., M ovata Delile ex Moq., Schollera debilis (Sw.) Rohr.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 3 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 11 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment of hepatocellular carcinoma and acute promyelocytic leukaemia

   Plant part used: Aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Pathak G (2021)

     Excerpt Cirsimaritin is a dimethoxy flavone, which is present in Ocimum sanctum, Microtea debilis, Artemisia Judaica, Cirsium japonicum, & Lithocarpus dealbatus. Its antiproliferative potential has been explored in breast & gall bladder cancer cell lines.

   • According to Bai N (2011)

     Excerpt Two new 5-O-glucosylflavones, 5-O-β-d-glucopyranosyl cirsimaritin (1) & 5, 4′-O-β-d-di-glucopyranosyl cirsimaritin (2), four known flavonoids, cirsimarin (3), cirsimaritin (4), salvigenin (5), 4′, 5-dihydroxy-7-methoxyflavone (6), & a norisoprenoid, vomifoliol (7), have been isolated from the aerial parts of Microtea debilis. All isolates were tested for cytotoxicity in human cancer cell lines (Hep G2, COLO 205, & HL-60) & anti-inflammatory activities in LPS-treated RAW264.7 macrophages.

   • According to Benali T (2022)

     Excerpt The identification & isolation of this flavonoid from various natural sources, including medicinal plants such as Artemisia judaica, Cirsium japonicum, Lithocarpus dealbatus, Microtea debilis, & Ocimum sanctum, has been carried out & verified using different spectral techniques. Indeed, this bioactive induces anti-inflammatory & antiproliferative effects by inhibiting cell membrane receptors, interference with signaling pathways, & inhibiting transcriptional factors such as Nf-κB involved in cell promotion & proliferation.

2. 2

   Osteoarthritis, arthritis, rheumatism, oedema

   Plant part used: Aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Bai N (2011)

     Excerpt Two new 5-O-glucosylflavones, 5-O-β-d-glucopyranosyl cirsimaritin (1) & 5, 4′-O-β-d-di-glucopyranosyl cirsimaritin (2), four known flavonoids, cirsimarin (3), cirsimaritin (4), salvigenin (5), 4′, 5-dihydroxy-7-methoxyflavone (6), & a norisoprenoid, vomifoliol (7), have been isolated from the aerial parts of Microtea debilis. All isolates were tested for cytotoxicity in human cancer cell lines (Hep G2, COLO 205, & HL-60) & anti-inflammatory activities in LPS-treated RAW264.7 macrophages.

   • According to Benali T (2022)

     Excerpt The identification & isolation of this flavonoid from various natural sources, including medicinal plants such as Artemisia judaica, Cirsium japonicum, Lithocarpus dealbatus, Microtea debilis, & Ocimum sanctum, has been carried out & verified using different spectral techniques. Indeed, this bioactive induces anti-inflammatory & antiproliferative effects by inhibiting cell membrane receptors, interference with signaling pathways, & inhibiting transcriptional factors such as Nf-κB involved in cell promotion & proliferation.

3. 3

   Cellulite

   Plant part used: Whole plant.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Bai N (2011)

     Excerpt Two new 5-O-glucosylflavones, 5-O-β-d-glucopyranosyl cirsimaritin (1) & 5, 4′-O-β-d-di-glucopyranosyl cirsimaritin (2), four known flavonoids, cirsimarin (3), cirsimaritin (4), salvigenin (5), 4′, 5-dihydroxy-7-methoxyflavone (6), & a norisoprenoid, vomifoliol (7), have been isolated from the aerial parts of Microtea debilis. All isolates were tested for cytotoxicity in human cancer cell lines (Hep G2, COLO 205, & HL-60) & anti-inflammatory activities in LPS-treated RAW264.7 macrophages.

   • According to Benali T (2022)

     Excerpt The identification & isolation of this flavonoid from various natural sources, including medicinal plants such as Artemisia judaica, Cirsium japonicum, Lithocarpus dealbatus, Microtea debilis, & Ocimum sanctum, has been carried out & verified using different spectral techniques. Indeed, this bioactive induces anti-inflammatory & antiproliferative effects by inhibiting cell membrane receptors, interference with signaling pathways, & inhibiting transcriptional factors such as Nf-κB involved in cell promotion & proliferation.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.