Nasturtium officinale (Watercress) : medicinal properties in alcoholic extraction

Nasturtium officinale (Watercress, Kréson, Cresson) — family Brassicacées.

Scientific synonyms : Baeumerta nasturtium-quaticum (L.) H, Cardamine nasturtium (Moench) K, Radicula nasturtium (Moench) Druce, Roripa nasturnium aquaticum-(L)-HK, Sisymbrium nasturtium (Moench) Willd...

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 14 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 74 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: aerial parts. Mentioned synergistic association: Sansevieria trifasciata-feuille.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to AMELIANI S (2024)

     Excerpt Br) & tongue-in-law (Sansevieria trifasciata Prain) plants have the potential to treat diabetes. Diabetes mellitus (DM) is a chronic metabolic disorder characterized by hyperglycemia.

   • According to Al-Snafi AE (2020)

     Excerpt Al-Snafi AE, A review on Nasturtium officinale: A potential medicinal plant, J of Pharm, 10(9):33-43, 2020-Abtarct: The chemical analysis of Nasturtium officinale showed the presence of alkaloids, flavonoids, saponins, terpenoids/steroids, protein, essential and volatile oils, glycosides, tannins, folic acid, vitamins & elements. The current review highlighted the chemical ingredients & pharmacological effects of Nasturtium officinale.

   • According to GHeyni MH (2010)

     Excerpt In this study, the effect of oral administration of Nasturtium officinale on serum levels of glucose & lipids, as well as morphology of Langerhans islets in diabetic rats was investigated. For statistical analysis of data, Repeated measurement & One-way ANOVA tests were applied using Sigma Stat.Results: Treatment of diabetic rats did have a significant hypoglycemic effect (p<0.01).

   • According to Shahrokhi N (2009)

     Excerpt For treating diabetic patients, different nutrients are being used in some areas of Kerman province, Nasturtium officinale (NF) is one of them. All rats randomly divided into six groups, consisting of one intact non- diabetic group, & remaining 5 groups were injected subcutaneously of 55 mg/Kg of streptozotocin to make them experimentally diabetic.

   • According to Kijkuokool P (2024)

     Excerpt Nasturtium officinale R.Br. This study aimed to assess the effect of drying methods on the phytochemical contents, antioxidant activity, & anti-diabetic activity of Betong watercress.

2. 2

   Cancer: adjuvant treatment for uterine carcinoma

   Plant part used: aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Tavarati Aet al (2017)

     Excerpt The hydroalcoholic extract of watercress can inhibit the growth of Hella cells & can be considered as an alternative for cervical cancer treatment in the future. Rorippa nasturtium aquaticum, also called watercress, is a plant from the Brassicaceae family which has large amounts of antioxidants.

   • According to Yalçinkaya E (2019)

     Excerpt Nasturtium officinale has been used for a long time as a food & medicinal plant. The aim of this study is to make review about the previous reports on secondary metabolites of Nof in terms of or their effects against various cancer cell lines.

   • According to Klimex-Sczkutowicz M (2018)

     Excerpt The herb of Nasturtium officinale is a raw material that has long been used in the traditional medicine of Iran, Azerbaijan, Morocco & Mauritius. Nowadays, this raw material is the object of numerous professional pharmacological studies that have demonstrated its antioxidant, anticancer, antibacterial, anti-inflammatory and cardioprotective properties.

   • According to Fallah N (2016)

     Excerpt MDA-MB-231 breast cancer cells have been treated with different concentrations of NOf extract (0 - 2 mg/mL) & after 24, 48, and 72 hours of incubation, cell viability test was performed through MTT Assay to investigate the inhibitory effect of Nof extract on cancer cells. Objectives The objective of this original paper is to study the inhibitory effects of different concentrations of NOf hydroalcoholic extract on growth inhibition of breast cancer & normal cells.

   • According to Sefidkon F (2013)

     Excerpt Results of anticancer properties of the extract & fractions of Nof on both breast & colon cancer cells, for 1 to 3 days, showed that dichloro-methane fraction had a stronger effect on inhibition of proliferation of cancer cells compared to the first extract & other fractions. Meanwhile, the anticancer effect of NOf extract on breast cancer cells was stronger than that on colon cancer cells.

3. 3

   Oxidative stress

   Plant part used: aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Sedaghattalab M (2021)

     Excerpt Nasturtium officinale contains numerous phytochemical compounds that act as an antioxidant by preventing oxidative damage to biomolecules. Therefore, this research aimed to explore the effect of the ethanolic extract of Nasturtium officinale (EENO) on antioxidant & biochemical markers of hemodialysis patients.

   • According to Doustimotiagh HA (2020)

     Excerpt On day 11, all the animals were sacrificed, and their blood and liver were gathered for evaluation of the liver enzyme, hepatic oxidative stress markers, antioxidant enzymes activity, & hematoxylin & eosin staining. However, its therapeutic use is limited because of its severe side effects, especially hepatotoxicity attributed to oxidative stress.

   • According to Shahani S (2017)

     Excerpt The aim of our investigation was to evaluate the role of inflammation & also oxidative damage in nephrotoxic potential of GM & protective effects of Nasturtium officinale (watercress) against GM-induced nephrotoxicity in Wistar rats. Administration of NO extract was able to protect against deterioration in nephrotoxic markers & suppressed the increase in oxidative stress & inflammation markers.

   • According to Kiriakou S (2022)

     Excerpt Finally, levels of oxidative stress a&apoptotic induction were increased in both NOf samples, but the magnitude of the induction was much higher in the edible than the non-edible watercress samples. In addition, cell viability was evaluated by the Alamar Blue assay, whereas levels of oxidative stress & apoptosis were determined by commercially available kits.

   • According to Yazdanparast R (2008)

     Excerpt Nasturtium officinale R. This therapeutical application has been attributed to NOf antioxidant capacity which is mostly tested by means of cell-free assays: 2,2-diphenyl-1-picrylhydrazyl (DPPH) & ferric reducing antioxidant power (FRAP).

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.