Nyctanthes arbor (Night-blooming jasmine) : medicinal properties in alcoholic extraction

Nyctanthes arbor (Night-blooming jasmine, Jasmin de nuit) — family Oleacacées.

Scientific synonyms : Bruschia macrocarpa-Bertol, Cabrita triflora-L, Nyctanthes tristis-Salisb, Parilium arbortristis-(L.)-Gaertn..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 15 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 31 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Bacterial and fungal infections: Staphylococcus aureus, Bacillus subtilis (NCIM 2063), Escherichia coli, Salmonella typhimurium, Streptococcus pneumoniae and Candida albicans

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Agrawal MK (2016)

     Excerpt Staphylococcus aureus (NCIM 2079), Bacillus subtilis (NCIM 2063), Escherichia coli (NCIM 2065), Salmonella typhimurium (NCIM 2501), Streptococcus pneumoniae (NCIM 5281) & a yeast Candida albicans (NCIM 3471). Overall, broad-spectrum antibacterial activity was observed in 08 plants (ethanolic extracts) & 06 plants (aqueous extracts) against all test bacteria & 07 plants (ethanolic extracts) & 05 plants (aqueous extracts) against Candida albicans.

2. 2

   Cancer: adjuvant treatment of carcinoma: breast (hormone-dependent or hormone-independent), colorectal, liver, chronic myeloid leukaemia, uterine and retinoblastoma

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Khanapur M (2014)

     Excerpt The present study was intended to evaluate the antioxidant & antiproliferative activities of flower extracts of N arbortristis. The antiproliferative activity was carried out by MTT assay by employing different human cancer cell lines.

   • According to Rathore B (2007)

     Excerpt To study the modulation effect of pro- & anti-inflammatory cytokines following long term use of water-soluble ethanol extracts from different organs of Nyctanthes arbortristis (NAT) in mouse model of arthritis. Oral administration of leaf & fruit extracts in arthritic mice reduced joint homogenate levels of tumor necrosis factor-α, interleukin-1β, & interleukin-6 on days 2, 14, & 47 in comparison to untreated arthritic mice.

   • According to Din-Amani M (2009)

     Excerpt Tumor incidence was found to be higher in the control group as compared to treated groups. There was a significant difference in tumor burden, tumor yield (p<0.05) obsd.

   • According to Khatune NA (2003)

     Excerpt on Ehrlich ascites carcinoma cell (EAC) in mice, J of Med Sci, 3 (2): 169–73, 2003-Abstrract: The potential cytotoxic effect of a new benzofuran derivative, 4-hydroxy hexahydrobenzofuran-7-one isolated from Nyctanthes arbor-tristis was evaluated on Ehrlich Ascites Carcinoma (EAC) cells in Swiss Albino mice. 4-Hydroxy hexahydrobenzofuran-7-one was administered in a daily dose of 20 mg kg¹ of mouse after inoculation of Ehrlich Ascites Carcinoma (EAC) cell to the mice.

   • According to Timsina B (2016)

     Excerpt By thin layer chromatography we could isolate six fractions each from the flower extract & the leaf extract, out of which fraction 3 from the flower & fraction 5 from the leaves have exhibited maximum antiproliferative effects with an IC50 value of 10 μg/ml on HeLa cells, 5 μg/ml on HepG2 cells and > 200 μg/ml on normal lymphocytes, indicating that they are least toxic to the healthy cells. This study aims at the extraction of bioactive metabolites from the flowers & leaves of parijat (Nyctanthes arbortristis Linn.) & Evaluation of their cytotoxic properties on HeLa cells, HepG2 cells & also on normal human peripheral lymphocytes.

3. 3

   Malaria: Plasmodium berghei

   Plant part used: Pest control and veterinary products.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Misra P (1991)

     Excerpt Alcoholic extracts of 44 plants were screened in vivo & in vitro for antimalarial activity against the NK 65 strain of Plasmodium berghei. Jurinea macrocephala, Artemisia scoparia, Nyctanthes arbor-tristis, Eniscostema hyssopifolium, Aegle marmelos, Cinnamomum tamala, Momordica dioica & Prunus persica were found to possess schizonticidal activity (50% & above) in vivo as well as in vitro at a dose of 1 gm/kg × 4 days & 100 μg/ml respectively, whereas 12 other plant extracts were active only in vivo & 3 plant extracts in in vitro only.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.