Osmanthus fragans (Dité dou) : medicinal properties in alcoholic extraction

Osmanthus fragans (Dité dou, Sweet tea, Thé sucré) — family Oleacacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 6 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 87 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment of colorectal and liver carcinoma

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to TSAI PJ (2017)

     Excerpt The excess influx of free fatty acids (FFAs) into nonadipose tissues, such as those of liver & kidney, induces lipotoxicity leading to hepatic steatosis & renal dysfunction. The aim of this study was to investigate the protective effects of methanolic flower extracts of Osmanthus fragrans (OF) & Chrysanthemum morifolium (CM) against FFA-induced lipotoxicity in hepatocytes (human HepG2 cells) & renal glomerular mesangial cells (mouse SV40-Mes13 cells).

   • According to Wang B (2022)

     Excerpt Pharmacological studies demonstrated that OF & its active components had a wide range of biological activities, such as antioxidant, antitumor, anti-inflammatory, anti-hyperglycemic, anti-thrombotic, anti-melanogenesis, neuroprotective, & hepatoprotective activities, etc. Osmanthus fragrans Lour., is a medicinal plant distributed widely in some Asian countries including Japan & Korea & southwestern China.

   • According to Fu CC (2022)

     Excerpt It was found that the pharmacological activities of these secondary metabolites mainly include antioxidant, anticancer, anti-inflammatory & antibacterial activities & that these metabolites can be used to treat many human diseases, such as cancer, skin diseases, cardiovascular diseases, & neurological diseases. Osmanthus fragrans (scientific name: Osmanthus fragrans (Thunb.) Lour.) is a species of the Osmanthus genus in the family Oleaceae, & it has a long history of cultivation in China.

   • According to Wu L (2022)

     Excerpt Modern pharmacological researches demonstrated that OF possesses a broad spectrum of biological activities including antioxidant, neuroprotective, antidiabetic & anticancer activities etc. Not only the OF flowers, but also leaves, barks, roots, & fruits possess some beneficial effects such as relieving pain & alleviating cough in Traditional Chinese Medicine.

   • According to HAN S (2024)

     Excerpt Materials & methods: Ethanol (EtOH) extracts of OF leaf & flower, along with specific fractions (n-hexane, ethyl acetate (EtOAc), n-butanol, & the aqueous residue) were evaluated for their anti-proliferative effects in human CRC cells using MTT assays, & compared to normal colon cells. Notably, two triterpenoids isolated from the leaf EtOAc fraction, maslinic acid & corosolic acid, displayed potent anti-cancer activity in CRC cells without affecting normal colon cells.

2. 2

   Osteoporosis

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to SEO YS (2023)

     Excerpt The aim of this study was to evaluate the anti-osteoporosis effects of Osmanthus fragrans leaf ethanol extract (OFLEE) in bone marrow-derived macrophages (BMM) & animals with osteoporosis. Our findings suggest that OFLEE, with anti-inflammatory effects, prevents osteoporotic bone loss through the suppression of osteoclastic differentiation in BMM & animals with osteoporosis,.

   • According to LU B (2015)

     Excerpt Materials & methods: The OFFE was extracted by 80% (v/v) aqueous ethanol with 0.01% sodium isoascorbate (w/v) from the OF flower & purified on HPD300 resins. An acute oral toxicity study, reverse mutation test, bone marrow cell micronucleus test, & sperm abnormality test as well as a 90-day oral toxicity study were performed on experimental animals.

3. 3

   Allergy

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Hung CY (2013)

     Excerpt Thus, our findings confirm the ability of the OF flowers to reduce phlegm & suggest that OFE may be useful as an antiallergic agent. The Osmanthus fragrans flower, a popular herb in Eastern countries, contains several antioxidant compounds.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.