Oxalis corniculata (Little yellow clover) : medicinal properties in alcoholic extraction

Oxalis corniculata (Little yellow clover, Little yellow sirèt, Little clover, Little yellow sorrel, Little yellow surette, Ti-lozèy jôn, Ti-Sirèt jôn, Ti-trèf, Petite oseille jaune, Petite surette jaune, Petit Trèfle) — family Oxalidacées.

Scientific synonyms : Oxalis repens-Thunb.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 15 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 56 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Diabetic neuropathic pain, sciatica

   Plant part used: Whole plant.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Sampath KV (2012)

     Excerpt In this study we tried to evaluate the antioxidant, antinociceptive activities of ethanolic extract of Oxalis corniculata in experimentally induced diabetic rats. Diabetic neuropathy is damage to nerves in the body that occurs due to high blood sugar levels from diabetes.

   • According to Senthil Kumar KK (2010)

     Excerpt Β-sitosterol, betulin, 4-hydroxybenzoic acid, ethyl gallate, methoxyflavone, apigenin, & 7-O-β-D-glucopyranoside were previously isolated from the whole plant of Oxalis corniculata, The review reveals that wide ranges of phytochemical constituents have been isolated from the plant like flavanoids, tannins, phytosterols phenol, glycosides, fatty acids, Galacto-Glycerolipid and volatile oil. It has been reported that the plant contains anti-inflammatory, anxiolytic, anticonvulsant, antifungal, antiulcer, antinociceptive, anticancer, antidiabetic, hepatoprotective, hypolipidemic, abortifacient, antimicrobial & wound healing properties.

   • According to Zhang S (2018)

     Excerpt The plant possesses many important activities like antioxidant [4], antibacterial, antifungal [5, 6], anticancer, anthelmintic, anti-inflammatory, anxiolytic, anticonvulsant, antiulcer, antinociceptive, antidiabetic, analgesic, antiamoebic, astringent, depurative, diuretic, febrifuge, cardiorelaxant, & stomachic [2, 3, 7]. The plant Oxalis corniculata L., also called creeping wood sorrel, is an important species of this genus occurring in China, the Philippines, India, & Pakistan [1, 2].

2. 2

   Normalisation of serum parameters: bilirubin, AST, ALT and ALP

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Sreejith G (2014)

     Excerpt Rats pretreated with OC for 4 days showed significant reduction in the serum enzymes such as glutamate oxaloacetate transaminase, glutamate pyruvate transaminase, alkaline phosphatase, serum Bilirubin & showed almost normal Histological liver architecture of the treated groups compared to paracetamol induced hepatic damage group, indicating its hepatoprotective & antioxidant potential. corniculata to alleviate liver damage caused by over dose of paracetamol.

   • According to Das K (2012)

     Excerpt The hepatoprotective activity of aqueous & ethanolic leaves extracts of Oxalis corniculata Linn. corniculata aqueous and ethanolic leaves extract at 400 mg/kg resulted in a significant reduction in SGOT (146.42±2.54 & 136.75±1.37 IU/L respectively), SGPT (81.96±3.15 & 72.05±2.33 IU/L respectively), GGTP (16.6±0.49 & 15.02±0.68 IU/L respectively), ALP (241.86±3.94 & 202.42±5.37 IU/L respectively) & total Bilirubin (0.226±0.00 mg/dL 0.288±0.01 mg/dL respectively) content that were lesser than positive control, thioacetamide damaged rats.

   • According to Jadhav AG (2021)

     Excerpt Methods: The hepato-protective activity of the formulation & extracts were assessed on the basis of histopathological changes in the liver & estimation of SGOT, SGPT, SALP, serum bilirubin of carbon tetrachloride-induced hepato-toxic rats. To investigate the hepatoprotective activity of polyherbal formulation composed of extracts of Bauhinia variegata, Oxalis corniculata, & Pterocarpus marsupium.

   • According to Khan MR (2012)

     Excerpt Khan MR et al, Antioxidant & hepatoprotective effects of Oxalis corniculata against carbon tetrachloride (CCl4) induced injuries in rat.

   • According to Kathiriya A (2010)

     Excerpt Present investigations were carried out to evaluate an ethanolic extract of Oxalis corniculata Linn. Cancerous animals were divided into four groups having six mice in each in which Group III & IV cancerous animals were treated with the ethanolic extract of O corniculata.

3. 3

   Hepatitis, cirrhosis, hepatic

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Jadhav AG (2021)

     Excerpt To investigate the hepatoprotective activity of polyherbal formulation composed of extracts of Bauhinia variegata, Oxalis corniculata, & Pterocarpus marsupium. Methods: The hepato-protective activity of the formulation & extracts were assessed on the basis of histopathological changes in the liver & estimation of SGOT, SGPT, SALP, serum bilirubin of carbon tetrachloride-induced hepato-toxic rats.

   • According to Sreejith G (2014)

     Excerpt Rats pretreated with OC for 4 days showed significant reduction in the serum enzymes such as glutamate oxaloacetate transaminase, glutamate pyruvate transaminase, alkaline phosphatase, serum Bilirubin & showed almost normal Histological liver architecture of the treated groups compared to paracetamol induced hepatic damage group, indicating its hepatoprotective & antioxidant potential. corniculata to alleviate liver damage caused by over dose of paracetamol.

   • According to Das K (2012)

     Excerpt The hepatoprotective activity of aqueous & ethanolic leaves extracts of Oxalis corniculata Linn. corniculata aqueous and ethanolic leaves extract at 400 mg/kg resulted in a significant reduction in SGOT (146.42±2.54 & 136.75±1.37 IU/L respectively), SGPT (81.96±3.15 & 72.05±2.33 IU/L respectively), GGTP (16.6±0.49 & 15.02±0.68 IU/L respectively), ALP (241.86±3.94 & 202.42±5.37 IU/L respectively) & total Bilirubin (0.226±0.00 mg/dL 0.288±0.01 mg/dL respectively) content that were lesser than positive control, thioacetamide damaged rats.

   • According to Khan MR (2012)

     Excerpt Khan MR et al, Antioxidant & hepatoprotective effects of Oxalis corniculata against carbon tetrachloride (CCl4) induced injuries in rat.

   • According to Author (2014)

     Excerpt The aim of the present study was to evaluate the LD50 & hepatorenal toxicity of the ethanolic extracts of Common weed plants: Oxalis corniculata L. Conclusion: It is therefore concluded that the dose below LD50 value of ethanolic extracts of O corniculata & P fraternus may safety be used for therapeutic purposes.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.