Parthenium hysterophorus (Matritjè) : medicinal properties in alcoholic extraction

Parthenium hysterophorus (Matritjè, Matricaire) — family Asteracées.

Scientific synonyms : Parthenium Villanova-Ortega, P Bolophyta-Nutt., P Partheniastrum-Fabr., P Echetrosis-Phil., P Hysterophorus-Vall., P Argyrochaeta-Cav..

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 15 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 120 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Bashir S (2021)

     Excerpt hysterophorus) is used to treat diabetes mellitus in local medicinal system of Pakistan but very limited scientifically proved information is available in this context. The experimental outcomes may be employed as pharmacological leads to treat diabetes mellitus & to develop functional foods with hypoglycemic attributes.

   • According to Vijay PS (2008)

     Excerpt Vijay PS et al: Hypoglycemic effect of aqueous extract of Parthenium hysterophorus L. in normal & alloxan induced diabetic rats Indian J Pharmacol; 40(4): 183–185, 2008.

   • According to Kaur L (2021)

     Excerpt Despite its detrimental effects, PH is widely used as a folk remedy against various infections for fever, diabetes, insomnia, skin inflammation, analgesic. In India, Parthenium or Gajar Ghans is the most common invasive species and is recognized as Congress grass.

   • According to Kaur L (2021)

     Excerpt Parthenium hysterophorus is a noxious weed & a species of flowering plant in the Asteraceae family. The extracts obtained from PH have anti-inflammatory, antioxidant, larvicidal, anti-microbial, insecticidal, hypoglycaemic & anti-cancer activity.

2. 2

   Cancer: adjuvant treatment for leukaemia

   Plant part used: Sheet. Mentioned synergistic association: Hedyotis corymbosa.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Pandey K (2012)

     Excerpt To study the anticancer activity of ethanolic extract of leaves of Parthenium hysterophorus & Oldenlandia corymbosa by SRB assay method on K562 human leukemia cancer cell line. Results: P hysterophorus & O corymbosa showed significant anticancer activity on K562 human leukemia cancer cell line.

   • According to Kumar S (2013)

     Excerpt Ethanol fraction showed noticeable cytotoxic activity (81-85%) in SRB assay against MCF-7 & THP-1 cancer cell lines at 100 μg/ml concentration, while lower activity was observed with DU-145 cell line. The same extract exhibited 17-98% growth inhibition of HL-60 cancer cell lines in MTT assay, showing concentration dependent response.

   • According to Kaur M (2020)

     Excerpt P hysterophorus s an invasive obnoxious weed capable of surviving extreme environmental conditions & various parts of this plant are reported to cause severe contact allergies in humans due to the presence of high concentrations of toxic sesquiterpene lactones viz. The effect of PH flower extract was evaluated on cell viability, oxidative stress & inflammation in A549 lung cancer cell line by spectrophotometric & reverse transcriptase-polymerase chain reaction methods.

   • According to Panwar R (2015)

     Excerpt Parthenium hysterophorus is a globally recognized invasive alien weed that prominently colonizes grazing areas & cultivated lands causing adverse effect on crop production. Anticancer activity of PH phenolic extract against A-498 (IC50 0.5237 µg/ml) & MDA-MB231 (IC50 & 0.2685 µg/ml) cancerous cell lines indicated its potential to be used as anticancer agent,.

   • According to DIAZ-GARCIA A (2011)

     Excerpt RESULTS: the ethanolic extracts of Parthenium hysterophorus, Bixa orellana, Momordica charantia & Cucurbita maxima showed mean cytotoxic concentrations under 100 µg/mL. CONCLUSIONS: the plant extracts for cancer treatment in traditional medicine showed cytotoxic effect on the tumor cell lines.

3. 3

   Bacterial infection: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa

   Plant part used: Flowering stem.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to -Sharif N (2021)

     Excerpt Variable results of antimicrobial activity against, Salmonella paratyphi A, Pseudomonas aeruginosa, Proteus mirabilis & Escherichia coli were obtained. The present study was conducted to find out the antibacterial potential of Parthenium hysterophorus.

   • According to Fazal H (2011)

     Excerpt The extracts were tested against Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Bacillus subtilis, Enterococcus spp., & Staphylococcus aureus by using agar well diffusion method. In the present study the, In-vitro antibacterial activity of 3 medicinal plants viz., Parthenium hysterophorus, Stevia rebaudiana & Ginkgo biloba were evaluated by using different solvent extracts.

   • According to Datta S (2001)

     Excerpt Phytochemical screening & Antifungal activities of Parthenium hysterophrous was carried out in laboratory. The antifungal activity of extracts was determined by poisoned food technique; & linear mycelium growth reduction (LMGR) percentage was calculated.

   • According to Harsha Madan (2011)

     Excerpt Harsha Madan et al, Antimicrobial & Spermicidal activities of Parthenium hysterophorus Linn.

   • According to Teveswari K (2016)

     Excerpt Teveswari K et al, Study on Antibacterial Activity of Parthenium hysterophorus.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.