Paullinia pinnata (Lyenn-Pèsi) : medicinal properties in alcoholic extraction

Paullinia pinnata (Lyenn-Pèsi, Liane-parsley, Lyenn-Pèsi, Liane-persil) — family Sapindacées.

Scientific synonyms : Paullinia diversifolia-Miq, P hostamannii-steud.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 7 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 33 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Bacterial infection: Enterobacter cloacae, Klebsiella pneumoniae, Escherichia coli, Shigella flexneri, Proteus mirabilis, Salmonella typhi and Bacillus cereus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Afagnigni AD (2016)

     Excerpt Antibacterial assay was performed using agar well diffusion & microdilution methods against seven clinical isolates namely Enterobacter cloacae, Klebsiella pneumoniae, Escherichia coli, Shigella flexneri, Proteus mirabilis, Salmonella typhi & Bacillus cereus. This study aimed at investigating the in vitro antibacterial and antioxidant activities of ethanolic leaves of Paullinia pinnata.

   • According to Ikhane D (2015)

     Excerpt Phytochemical & Antimicrobial Activities of Methanolic Extract of Paullinia pinnata Leaves on Some Selected Bacterial Pathogens.

   • According to Annan K (2004)

     Excerpt Annan K et al, Antibacterial activity of Paullinia pinnata extracts.

   • According to Lasisi AA (2012)

     Excerpt new triterpene isovanniloyl & antibacterial activity of constituents from the roots of Paullinia pinnata Linn (Sapindaceae).

   • According to Nyegue MA (2020)

     Excerpt Herbal products from Paullinia pinnata Linn are widely used in African folk medicine to treat several infectious diseases. Diarrhea was induced by oral administration of 1.2 × 109 CFU/mL of Shigella flexneri to the rats.

2. 2

   Cancer: adjuvant treatment for liver, breast, lung and uterine cancer

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Kola P (2023)

     Excerpt Material & methods: Breast, lung, cervical, & liver cancer cell lines were exposed to the extracts, & viability was assessed using the Sulforhodamine B method. In our previous study, extracts from four Togolese plants, namely, Cochlospermum planchonii (CP), Piliostigma thonningii (PT), Paullinia pinnata (PP), & Securidaca longipedunculata (SL), actually used in traditional medicine for cancer treatment, showed beneficial health effects against oxidative stress, inflammation, & angiogenesis.

   • According to Kola P (2021)

     Excerpt Methods: Four species, Cochlospermum planchonii (CP), Piliostigma thonningii (PT), Paullinia pinnata (PP), & Securidaca longepedunculata (SL) were selected & analyzed to detect the phytochemical components. In order to assess Togolese traditional healer's claims about the anticancer potential of medicinal plants & obtain candidate plants for anticancer drug discovery, some species were selected from surveys & evaluated for their antioxidant, anti-inflammatory, anti-angiogenic & cytotoxic activities.

   • According to Nyegue MA (2020)

     Excerpt Herbal products from Paullinia pinnata Linn are widely used in African folk medicine to treat several infectious diseases. Liver & kidney histology were modified at the dose of 445.68 mg/kg while no change was observed at the doses of 111.42 & 222.84 mg/kg.

   • According to Adeyemo-Salami O (2013)

     Excerpt The aim of this study was to investigate the toxicological effects of the leaves of Paullinia pinnata Linn. The histopathological study showed that the lungs exhibited dose -dependent lymphocytic infiltrations & the pattern of occurrence of lesions observed in the liver was at a frequency of one rat per group at the 400 & 800 mg/kg body weight doses.

   • According to Ajibade MA (2022)

     Excerpt Leaf extracts of Paullinia pinnata L.

3. 3

   Helminthiasis: Ancylostoma caninum, Haemonchus contortus, Toxocara cati, and Trichuris vulpis

   Plant part used: Pest control and veterinary products.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Spiegler V (2016)

     Excerpt In this study, a hydroethanolic root extract was investigated for its phytochemical composition & in vitro activity against the free-living nematode Caenorhabditis elegans as well as the larval stages of the parasitic helminths Ancylostoma caninum, Haemonchus contortus, Toxocara cati, & Trichuris vulpis.LC-MS analysis of the ethanol-water (1 : 1) extract revealed epicatechin & different A-type linked oligomeric & polymeric procyanidins as the predominant compounds.Within an in vitro mortality assay, the extract showed a lethal activity against T. Paullinia pinnata is a medicinal plant traditionally used in West Africa against a wide range of diseases including soil-transmitted helminthiases.

   • According to Spiegler V (2020)

     Excerpt Extracts from the roots of Paullinia pinnata L. Based on the results of an ethnopharmacological survey in Ghana, an aqueous acetone (70%) extract was investigated for its anthelmintic & phytochemical properties.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.