Peperomia pellucida (Zèb-kouwès) : medicinal properties in alcoholic extraction

Peperomia pellucida (Zèb-kouwès, herbe-à-couresse) — family Pipéracées.

Scientific synonyms : Peperomia translucens -Trel., Piper concinnum-Haw., Piper pellucidum-L..

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 12 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 74 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Bacterial infection: Staphylococcus aureus, Bacillus subtilis, Proteus mirabilis, Pseudomonas fluorescens

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Zubair KL (2013)

     Excerpt Ethanol extract of the plant had higher inhibitory action against Staphylococcus aureus, Bacillus subtilis, Proteus mirabilis & Pseudomonas fluorescens. pellucida were designed to evaluate for their possible antimicrobial, thrombolytic & antidiarrhoeal activities by using standard drugs: Penicillin for antimicrobial, streptokinase (SK) for thrombolytic & Loperamide for antidiarrhoeal activities.

   • According to Concepción CD (2017)

     Excerpt To determine the antibacterial properties of Peperomia Pellucida. The study aims to identify the antibacterial properties of the Pansit-pansitan that is responsible for treating or healing the open wounds.

   • According to Hastuti US (2017)

     Excerpt Hastuti US et al, Antifungal activity of Piper aduncum and Peperomia pellucida leaf ethanol extract against Candida albicans AIP Conf Proceedings 1844, 020006 (2017) / doi: 10.1063/1.4983417,.

   • According to Khan MR (2002)

     Excerpt Khan MR et al, Antibacterial activity of Hygrophilla stricta & Peperomia pellucida.

   • According to Ragasa CY (1998)

     Excerpt Ragasa CY et al, Antifungal compounds from Peperomia pellucida.

2. 2

   Infections in catfish (Clarias gariepinus): Streptococcus sp., Bacillus cereus, Klebsiella sp., Enterobacter aerogenes, Escherichia coli

   Plant part used: Pest control and veterinary products.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Awe FA (n.d.)

     Excerpt The identified bacterial pathogen includes Streptococcus sp, Bacillus Cereus, Klebsiella sp, Enterobacter aerogenes and Escherichia coli. The study was conducted to investigate the antibacterial activity of ethanolic extract of Acalypha wilkesiana & Peperomia pellucida leaves against Catfish infected with bacterial fin-rot.

   • According to Zubair KL (2013)

     Excerpt pellucida were designed to evaluate for their possible antimicrobial, thrombolytic & antidiarrhoeal activities by using standard drugs: Penicillin for antimicrobial, streptokinase (SK) for thrombolytic & Loperamide for antidiarrhoeal activities. Peperomia pellucida is a medicinal herb belonging to the family of Piperaceae-Pepper.

   • According to Concepción CD (2017)

     Excerpt To determine the antibacterial properties of Peperomia Pellucida. The study aims to identify the antibacterial properties of the Pansit-pansitan that is responsible for treating or healing the open wounds.

   • According to Hastuti US (2017)

     Excerpt Hastuti US et al, Antifungal activity of Piper aduncum and Peperomia pellucida leaf ethanol extract against Candida albicans AIP Conf Proceedings 1844, 020006 (2017) / doi: 10.1063/1.4983417,.

   • According to Khan MR (2002)

     Excerpt Khan MR et al, Antibacterial activity of Hygrophilla stricta & Peperomia pellucida.

3. 3

   Cancer: adjuvant treatment of colorectal carcinoma, monocytic leukaemia

   Plant part used: Aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Pappachen LK (2013)

     Excerpt the presents study involves in the investigation of various extracts of Peperomia Pellucida for its phytochemical constituents & the cytotoxic potential, Qualitative phytochemical analysis of the plant extracts were done & all the extracts were screened for in vitro cytotoxic activity by MTT assay method using HEK 293 (Human Epithelial Kidney cell line), HeLa (Human cervical cancer cell line) & HePG2 (Human hepatic carcinoma cell line).It was found that the presence of phytochemicals were maximum in the methanol extract of P Pellucida when compared to other extracts and the methanol extract showed significant cytotoxic activity than all the other extracts against the above mentioned cancer cell lines while was found to be less cytotoxic against normal human kidney cells(HEK 293) displaying safety for normal cells.

   • According to Xu S (2006)

     Excerpt Five new compounds (1−5), including two secolignans, two tetrahydrofuran lignans & one highly Methoxylated dihydro-naphthalenone, were isolated from the whole plant of Peperomia pellucida. Compound 1 & peperomin E show growth inhibitory effects on the three cancer cell lines with 50-IC values ranging between 1.4 & 9.1 & between 1.8 & 11.1 m-M, respectively.

   • According to Buhian PS (2019)

     Excerpt The cytotoxicity of methanolic & ethanolic extracts from the plant locally known as "Pansit-pansitan" [Peperomia pellucida (L.) HBK] on human cancer & normal cell lines was determined. Cytotoxicity was tested on human colorectal adenocarcinoma cells (HT-29), human monocytic leukemia cells (THP-1) & normal human fibroblast & liver cells (HDFn & THLE-3, respectively) using Presto Blue® resazurin assay.

   • According to Wei LS (2011)

     Excerpt Peperomia pellucida leaf extract was characterized for its anticancer, antimicrobial, antioxidant activities & chemical compositions. pellucida leaf extract possessed anticancer activities with half maximal inhibitory concentration (IC (50)) of 10.4 ± 0.06 µg/ml.

   • According to Mutee A F (2010)

     Excerpt The present study was performed to evaluate the anti-inflammatory and antioxidant effects of petroleum ether, chloroform & methanol extracts of P. The carrageenan-induced rat hind paw edema method was performed to evaluate the anti-inflammatory effect in vivo and the determination of free radical scavenging activity method was carried out to assess the antioxidant effect in vitro.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.