Physalis angulata (Pôk) : medicinal properties in alcoholic extraction

Physalis angulata (Pôk, Zèb-Klôch, Kôk-môl, bell-shaped herb, Soft cock, herbe-cloche, Coq mou) — family Solanacées.

Scientific synonyms : Physalis capsicifolia-Dunal, P linkiana-Nees, P ramossissima-Milld.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 24 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 97 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer in adjuvant treatment: liver cancer, kidney cancer, uterine cancer, hormone-dependent breast cancer

   Plant part used: Whole plant.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ribeiro IM (2002)

     Excerpt Physalis angulata L. The extract prepared from roots of PA is the most clinically used by Physicians for treatment of human hepatic disorders, despite the substance responsible for the efficacy still a matter of argument.

   • According to Rohmawati E (2021)

     Excerpt Ciplukan (Physalis angulata Linn.) is a Solanaceae family species & contains various active compounds with diverse therapeutic potential. Overall, in rat liver fibrosis induced by CCl4, these findings suggest that the ethyl acetate fraction of PA has an antifibrotic effect.

   • According to Le Tuan Anh H (2017)

     Excerpt Le Tuan Anh H et al, HEPATOPROTECTIVE EFFECTS OF PHENOLIC GLYCOSIDES FROM THE METHANOL EXTRACT OF PHYSALIS ANGULATA, J of Sci & Technol, 55(2) :161-7, 2017.

   • According to Yu P (2017)

     Excerpt Therefore, PP is a promising candidate for the development of antitumor drugs for the treatment of triple-negative breast cancer. Physagulide P (PP), a new natural compound, was isolated from Physalis angulata in our laboratory.

   • According to Author (2006)

     Excerpt Women's Health Weekly (2006-09-14), Breast cancer cell cycle arrest is induced by Physalis angulata.

2. 2

   Type II diabetes mellitus

   Plant part used: Root.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Oladele GM (2013)

     Excerpt angulata using alloxan induced diabetes mellitus in rats was also checked by analyzing their fasting blood glucose and lipid profile. Anti-diabetic potential of ethanolic root extract of P.

   • According to Pujari S (n.d.)

     Excerpt Pujari S et al, Anti-diabetic activity of Physagulin-F isolated from Physalis angulata fruits, The American J of SCI & MED RES, 1(1), 53-60.

   • According to Raju P (2015)

     Excerpt Raju P et al, Anti-diabetic activity of compound isolated from Physalis angulata fruit extracts in alloxan induced diabetic rats, The Am J Sci & Med Res, 1(1) :1-6, 2015.

   • According to Abo K (2013)

     Excerpt Abo K et al Anti-diabetic activity of Physalis angulata extracts & fractions in alloxan-induced diabetic rats.

   • According to Sateesh P (2014)

     Excerpt Sateesh P et al, Phytochemical analysis & in vitro anti-diabetic activities of Physalis angulata fruit extracts.

3. 3

   Inflammatory pain

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ukwibile CL (2016)

     Excerpt Ukwibile CL et al, Analgesic & Anti-inflammatory Activity of Physalis angulata Linn.

   • According to Choi EM (2003)

     Excerpt The anti-inflammatory activities of Piper cubeba (fruit), Physalis angulata (flower) & Rosa hybrida (flower) were determined by carrageenan-induced paw edema, arachidonic acid-induced ear edema & formaldehyde-induced arthritis in mice. These results provide support for the use of Rosa hybrida in relieving inflammatory pain & insight into the development of new agents for treating inflammatory diseases.

   • According to Arruda J.C.C. (2021)

     Excerpt possesses traditional uses & exhibits antiparasitic, anti-inflammatory, antimicrobial, antinociceptive, antimalarial, antileishmanial, immunosuppressive, antiasthmatic.

   • According to Jyothi-Basu T (2012)

     Excerpt Antiasthmatic activity of the alcoholic extract of Physalis angulata roots in ovalbumin induced experimental mice model. The present study indicates that Physalis angulata has significant antiasthmatic property.

   • According to Bastos GNT (2008)

     Excerpt Bastos GNT et al, Physalis angulata extract exerts anti-inflammatory effects in rats by inhibiting different pathways, J of Ethnopharmacol, 118(2) :246–251, 2008.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.