Pisonia aculeata (Kwôk-chien) : medicinal properties in alcoholic extraction

Pisonia aculeata (Kwôk-chien, Dog-catcher, Croc-à-chien) — family Nyctaginacées.

Scientific synonyms : Pisonia aculeata-(L)-Well, P aculeata var Pedicellaris-G ex H, P loranthoides Kunth, P monotaxadenia CW, P Sieberi S, P villosa Poir, P yagua-pinda DP.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 8 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 24 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Liver disease: cirrhosis, fatty liver, hepatitis, normalisation of serum parameters, ALT, ALP, SOD, GSH, creatinine, urea, etc.

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Anbarasu C (2012)

     Excerpt Conclusions: It can be concluded that PA extract possesses a remarkable hepatoprotective and antioxidant activity against TAA induced hepatotoxicity. to evaluate the protective effect of Pisonia aculeata on thioacetamide induced hepatotoxicity in rats.

   • According to Palanivel M (2008)

     Excerpt The plant extract (250 & 500 mg/kg, p.o.) showed a remarkable hepatoprotective a&antioxidant activity against carbon tetrachloride (CCl 4) -induced hepatotoxicity as judged from the serum marker enzymes and antioxidant levels in liver tissues. Ethanol extract of Pisonia aculeata (EPA) was evaluated for hepatoprotective and antioxidant activities in rats.

   • According to Anbarasu C (2011)

     Excerpt Methanolic extract of leaves of Pisonia aculeata (250 & 500 mg/kg, p.o.) showed a remarkable hepatoprotective and antioxidant activity against Rifampicin & Isoniazid induced hepatotoxicity as judged from the serum marker enzymes and antioxidant levels in liver tissues. Pisonia aculeata is traditionally used in treatment of liver disorder & thought to have a protective effect which may be beneficial to reduce symptoms of hepatotoxicity.

   • According to Anbarasu C (2011)

     Excerpt Anbarasu C et al, Protective effect of Pisonia aculeata on paracétamol induced hepatotoxicity in rats, J Exp Integr Med, 1(3): 167-72, 2011.

   • According to Mamoon Hussain S (2013)

     Excerpt Blood samples were collected on the 10th day for estimation of biochemical parameters (serum urea, serum creatinine, serum cholesterol, serum protein). Results: Both extracts were able to produce a significant hypoglycemic effect as well as reduction in serum urea, serum creatinine & serum cholesterol.

2. 2

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Mamoon Hussain S (2013)

     Excerpt The aim of the present study was to evaluate the antihyperglycemic effect of leaves of Pisonia aculeata (Family: Nyctaginaceae) on alloxan-induced diabetes in rats. Methods: Ethylacetate & ethanolic extract of the leaves of P aculeata were administered orally at doses of 100mg/kg & 200 mg/kg in normal and alloxan- induced diabetic rats.

   • According to Teja T (2013)

     Excerpt In this present study is an attempt to investigate its anti hyperlipidemic, anti diabetic activity of alcoholic extract of Pisonia aculeate (AEPA) based on the chemical constituents present in the plant. The potential activity was evaluated using albino wistar rats, the hypelipidemia was induced by Triton X diabetes was induced by administration of streptozotocin.

3. 3

   Swelling, oedema, rheumatic pain

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Anbalagan N (2002)

     Excerpt CE and ME were evaluated for analgesic, anti-inflammatory (acute & chronic) & diuretic activity at 2 dose levels (250 & 500 mg/kg). Significant analgesic & anti-inflammatory activities were associated with CE & ME.

   • According to Author (2013)

     Excerpt MATERIALS & METHODS: Analgesic & anti-inflammatory activities of MEPA (250 & 500 mg/kg) were evaluated using writhing, formalin, hot plate, tail flick, carrageenan-induced paw edema test, & membrane stabilizing activity. Pisonia aculeata leaves (Nyctagenaceae), a Folk medicinal plant used in the treatment of several inflammation, pain, & oxidative stress associated diseases.

   • According to Radha R (2008)

     Excerpt Radha R et al, Phytochemical analysis & anti-inflammatory activity of Pisonia aculeata R.Br.

   • According to Vandresen F (2013)

     Excerpt (Nyctaginaceae), Rev Latino Americana de Química, 41:2, 2013-ABSTRACT Pisonia aculeata (Nyctaginaceae) is a shrub widely used in Brazilian folk medicine, where the roots are used as purging & barks & leaves have anti-inflammatory properties. Vandresen F et al, Acute toxicity & antiedematogenic activity from stems of Pisonia aculeata L.

   • According to Sivaraj P (2020)

     Excerpt Sivaraj P et al, Antihypertensive Efficacy of Methanol Extracts of Pisonia aculeata L. It is used in the treatment of inflammation, pain & oxidative stress associated diseases.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.