Plectranthus barbatus (Doliprann’) : medicinal properties in alcoholic extraction

Plectranthus barbatus (Doliprann’, Doliprane) — family Lamiacées.

Scientific synonyms : Coleus forskohlii (Willd.) Briq., C barbatus (Andrews) Benth., Plectranthus forskohlii Willd.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 8 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 94 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment of gastric and liver carcinoma

   Plant part used: Root.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Battochio AP (2005)

     Excerpt Battochio AP et al, Water-soluble extract of Coleus barbatus modulates weight gain, energy utilization & lipid metabolism in secondary biliary cirrhosis: an experimental study in young rats.

   • According to Mastan A (2019)

     Excerpt The plant has been used since ancient times in ayurvedic traditional medicines for the treatment of hypertension, glaucoma, asthma, congestive heart failures, obesity, &d cancer.

2. 2

   Viraemia: HIV-1

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to ARAUJO SG (2014)

     Excerpt Phytol was a compound identified in all extracts by GC/MS, being majoritary component in Plectranthus barbatus & Rosmarinus officinalis. Ocimum basilicum, Plectranthus barbatus & Rosmarinus officinalis by gas chromatography/mass spectrometry (GC/MS).

   • According to Gelmini Department of Pharmaceutical Sciences, University of Milan, via Mangiagalli, 25 F (2015)

     Excerpt All EOs were tested for their in vitro antimicrobial activity, showing optimal growth-inhibition in antibiogram (∅>35 mm) & MIC tests (32–64 μg/mL) against Candida albicans, while EOs from leaves of both species showed a good activity (25 < ∅ < 34 mm, MIC 64–128 μg/mL) against Escherichia coli. Essential oils (EOs) from the roots, stems & leaves of P barbatus (A) & P caninus (B), cultivated in north Italy, were obtained by steam distillation & chemically characterised by gas chromatography–mass spectrometry.

   • According to MOTA L (2014)

     Excerpt Volatile‐oils chemical composition & bioactivity of the essential oils from Plectranthus barbatus, P. Aerial parts from these three related Plectranthus species were collected from cultivated plants grown in Portugal, during vegetative & flowering phases.

   • According to GELMINI F (2015)

     Excerpt Essential oils (EOs) from the roots, stems & leaves of P barbatus (A) and Plectranthus caninus (B), cultivated in North Italy, were obtained by steam distillation and chemically characterized by gas chromatography–mass spectrometry. All EOs were tested for their in vitro antimicrobial activity, showing optimal growth-inhibition in antibiogram (∅>35 mm) & MIC tests (32–64 μg/mL) against Candida albicans, while EOs from leaves of both species showed a good activity (25 < ∅ < 34 mm, MIC 64–128 μg/mL) against Escherichia coli.

   • According to Kapewangolo P (2018)

     Excerpt Plectranthus barbatus, a member of the Lamiaceae family, exhibits strong antioxidant activity, which appears to contribute to the reduction of viral load & other symptoms in human immunodeficiency virus (HIV)-1 infected individuals using this plant as treatment in a traditional medicine setting. barbatus extract has been shown to inhibit HIV-1 protease enzyme activity and whole virus replication in vitro, better than three other Plectranthus species (P.

3. 3

   Bacterial infection: Enterococcus faecalis, Staphylococcus aureus, Streptococcus mutans, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to ARAUJO SG (2014)

     Excerpt Phytol was a compound identified in all extracts by GC/MS, being majoritary component in Plectranthus barbatus & Rosmarinus officinalis. Ocimum basilicum, Plectranthus barbatus & Rosmarinus officinalis by gas chromatography/mass spectrometry (GC/MS).

   • According to Gelmini Department of Pharmaceutical Sciences, University of Milan, via Mangiagalli, 25 F (2015)

     Excerpt All EOs were tested for their in vitro antimicrobial activity, showing optimal growth-inhibition in antibiogram (∅>35 mm) & MIC tests (32–64 μg/mL) against Candida albicans, while EOs from leaves of both species showed a good activity (25 < ∅ < 34 mm, MIC 64–128 μg/mL) against Escherichia coli. Essential oils (EOs) from the roots, stems & leaves of P barbatus (A) & P caninus (B), cultivated in north Italy, were obtained by steam distillation & chemically characterised by gas chromatography–mass spectrometry.

   • According to GELMINI F (2015)

     Excerpt All EOs were tested for their in vitro antimicrobial activity, showing optimal growth-inhibition in antibiogram (∅>35 mm) & MIC tests (32–64 μg/mL) against Candida albicans, while EOs from leaves of both species showed a good activity (25 < ∅ < 34 mm, MIC 64–128 μg/mL) against Escherichia coli. Essential oils (EOs) from the roots, stems & leaves of P barbatus (A) and Plectranthus caninus (B), cultivated in North Italy, were obtained by steam distillation and chemically characterized by gas chromatography–mass spectrometry.

   • According to MOTA L (2014)

     Excerpt Volatile‐oils chemical composition & bioactivity of the essential oils from Plectranthus barbatus, P. Aerial parts from these three related Plectranthus species were collected from cultivated plants grown in Portugal, during vegetative & flowering phases.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.