Plumeria alba (White frangipani) : medicinal properties in alcoholic extraction

Plumeria alba (White frangipani, Franjipanié-blan, Frangipanier blanc) — family Plumeriacées.

Scientific synonyms : Plumeria hypoleuca Gasp..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 17 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 61 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum, Prevotella intermedia, Tannerella forsythia, Streptococcus mutans, Actinomyces viscosus, Streptococcus salivarius, C. albicans

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Chopra A (2022)

     Excerpt The antimicrobial properties of the extract were evaluated by testing the minimal inhibitory concentration, minimal bactericidal concentration, & well-diffusion assay against Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum, Prevotella intermedia, Tannerella forsythia, Streptococcus mutans, Actinomyces viscosus, Streptococcus salivarius, & Candida albicans. Although studies have confirmed that extracts from Plumeria species are effective against microbial infections & cancer, its role in managing oral diseases, particularly the chronic inflammatory disease of the gums (gingivitis & periodontitis), has never been explored.

   • According to Kaur J (2022)

     Excerpt Although studies have confirmed that extracts from Plumeria species are effective against microbial infections & cancer, its role in managing oral diseases, particularly the chronic inflammatory disease of the gums (gingivitis & periodontitis), has never been explored. Therefore, the current study aimed to explore the antimicrobial & cytotoxic properties of the PA flower extract against oral & periodontal pathogens compared to chlorhexidine & doxycycline.

   • According to Maulani A (2013)

     Excerpt Aggregatibacter actinomycetemcomitans is gram negative facultative anaerobic microorganism which is normally found in dental plaque. The goal of this study was to determine the antibacterial activity of PA ethanolic extract in inhibiting A actinomycetemcomitans growth.

   • According to Ningsih D R, (2018)

     Excerpt The plants that can be used as antifungal is white plumeria leaves (Plumeria alba L.). Candida albicans is one of fungi that can cause various infections.

   • According to Khaing W (2019)

     Excerpt Moreover three different solvents such as ethanol, ethyl acetate & n-hexane extracts of the sample were examined for their antimicrobial activities against Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus pumilus, Candida albicans & E. The main aim of the present research is to evaluate the biological activities of the root of Plumeria alba L, Firstly, phytochemical screening of the collected sample was performed.

2. 2

   Type II diabetes mellitus

   Plant part used: Root.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Mushtaq A (2017)

     Excerpt Methodology: In this study aqueous ethanolic extracts of Mentha spicata (leaves), Plumeria alba (leaves) & Nymphaea alba (flowers & rhizomes) were evaluated individually in 200mg/kg & 400mg/kg doses against alloxan (130mg/kg i.p.) induced hyperglycemic rats. Any impairment in the functionality of insulin leads to long lasting metabolic disorder called diabetes mellitus which can be described as a group of disorders i.e., hyperlipidemia, cardiomyopathy, nephritis, fatty liver & weight loss.

   • According to Tessou KZ (2013)

     Excerpt Plumeria alba Linn (Apocynaceae) is used in Togolese traditional medicine to treat diabetes mellitus & wounds.

   • According to Kadébé ZT (2014)

     Excerpt In Togo folk medicine, water infusion of Plumeria alba (Apocynaceae) root has a reputation for the local management & treatment for type 2 diabetes. In the oral glucose tolerance test, rats in treated group had a significant (p<0.001) reduction of blood glucose level during 180 min after glucose load, indicating that Plumeria alba root improved glucose tolerance.

   • According to Khaing W (2019)

     Excerpt The main aim of the present research is to evaluate the biological activities of the root of Plumeria alba L, Firstly, phytochemical screening of the collected sample was performed. The pharmacological studies were carried out to investigate antimicrobial activity, antioxidant activity, anti-hyperglycemic activity in vitro & acute toxicity in vivo.

   • According to Kadébé T (2016)

     Excerpt Conclusion: These results suggest that the total extract & fractions of PA exhibit significant antidiabetic & hypolipidemic properties in streptozotocin-induced diabetic animals. To investigate the effect of total hydroalcohol root extract of Plumeria alba (Apocynaceae) and its active fraction on diabetes in rats.

3. 3

   Periodontitis, dental caries, gingivitis: Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum, Prevotella intermedia, Tannerella forsythia, Streptococcus mutans, Actinomyces viscosus, Streptococcus salivarius, and Candida albicans

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Chopra A (2022)

     Excerpt The antimicrobial properties of the extract were evaluated by testing the minimal inhibitory concentration, minimal bactericidal concentration, & well-diffusion assay against Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum, Prevotella intermedia, Tannerella forsythia, Streptococcus mutans, Actinomyces viscosus, Streptococcus salivarius, & Candida albicans. Although studies have confirmed that extracts from Plumeria species are effective against microbial infections & cancer, its role in managing oral diseases, particularly the chronic inflammatory disease of the gums (gingivitis & periodontitis), has never been explored.

   • According to Maulani A (2013)

     Excerpt Aggregatibacter actinomycetemcomitans is gram negative facultative anaerobic microorganism which is normally found in dental plaque. The goal of this study was to determine the antibacterial activity of PA ethanolic extract in inhibiting A actinomycetemcomitans growth.

   • According to Kaur J (2022)

     Excerpt Although studies have confirmed that extracts from Plumeria species are effective against microbial infections & cancer, its role in managing oral diseases, particularly the chronic inflammatory disease of the gums (gingivitis & periodontitis), has never been explored. Plumeria alba, commonly known as frangipani or West Indian jasmine, is a traditional & ancient folklore medicine known for its antimicrobial, anti-inflammatory, & antioxidant properties.

   • According to Khaing W (2019)

     Excerpt Moreover three different solvents such as ethanol, ethyl acetate & n-hexane extracts of the sample were examined for their antimicrobial activities against Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus pumilus, Candida albicans & E. The main aim of the present research is to evaluate the biological activities of the root of Plumeria alba L, Firstly, phytochemical screening of the collected sample was performed.

   • According to Ningsih D R, (2018)

     Excerpt The plants that can be used as antifungal is white plumeria leaves (Plumeria alba L.). Candida albicans is one of fungi that can cause various infections.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.