Polygala paniculata (Lèsta-frajil) : medicinal properties in alcoholic extraction

Polygala paniculata (Lèsta-frajil, Salisilat, Ti-Branda, Esther fragile, Salicylate, Petit Branda) — family Polygalacées.

Scientific synonyms : Polygala paniculata.f-Humulis-Chodat, P.leucotera-SFBlake, var.Cartlotina-E.H. Krause.

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 8 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 15 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Pain, oedema

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to NOGUEIRA FLP (2005)

     Excerpt These results suggest that the ethanolic extracts from Wild and micropropagated Polygala paniculata possess Analgesic and antioedematogenic effects. The inhibition of ear oedema in mice was also observed after treatment with ethanolic extract of Polygala paniculata.

   • According to Wang H (2008)

     Excerpt Wang H et al, Anti-inflammatory activities of triterpenoid saponins from Polygala japonica.

   • According to Lapa F da R (2009)

     Excerpt The present study examined the antinociceptive effects of a hydroalcoholic extract of P paniculata in chemical & thermal behavioural models of pain in mice. The antinociceptive effects of hydroalcoholic extract was evaluated in chemical (acetic-acid, formalin, capsaicin, cinnamaldehyde & glutamate tests) & thermal (tail-flick & hot-plate test) models of pain or by biting behaviour following intrathecal administration of both ionotropic & metabotropic agonists of excitatory amino acids receptors glutamate and cytokines such as interleukin-1beta (IL-1beta) Tumour necrosis factor-alpha (TNF-alpha) in mice.

2. 2

   Candidiasis: Candida tropicalis & C. gatti

   Plant part used: Pest Control and Veterinary Products.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Johann S (2011)

     Excerpt paniculata showed antifungal activity against C. schenckii (1000 μg/mL of all the compounds screened, two of them showed antifungal inhibition, whereas eleven did not have significant activity.

3. 3

   Sporotrichosis: Sporothrix schenckii

   Plant part used: Pest Control and Veterinary Products.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Johann S (2011)

     Excerpt schenckii (1000 μg/mL of all the compounds screened, two of them showed antifungal inhibition, whereas eleven did not have significant activity. paniculata showed antifungal activity against C.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.