Porophyllum ruderale (Lawnika – savann’) : medicinal properties in alcoholic extraction

Porophyllum ruderale (Lawnika – savann’, Savannah arnica, Lawnika –savann’, Arnica de savane) — family Asteracées.

Scientific synonyms : Cacalia porophyllum-L, Kleinia ruderalis-Jacq, porophyllum ellipticum-Cass, P. ellipticum, var. genuine-Cass, P. porophyllum-(L)-Ktze, P. ellipticum-Cass, var. ruderale-(J)-Urb.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 8 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 36 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Oxidative stress

   Plant part used: Aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Kato da Silva B (2021)

     Excerpt Although a significant antioxidant activity was verified for the two concentrations analyzed, they were not sufficient to minimize the melanoma effects toxic in the mice liver as observed by histological changes & that leads us to conclude that the hydroalcoholic extract of aerial parts of PR, in the concentrations used, possesses antioxidant properties, good performance in inhibiting the proliferation of human melanoma cells, but it has no hepatoprotective effect in the melanoma cutaneous treatment,. The aim of this study was to evaluate the Porophyllum ruderale effects on the liver in murine melanoma model B16-F10 & to determine the antioxidant potential.

   • According to Conde-Hernandez LA (2014)

     Excerpt Extracts from fresh and dried samples of Mexican pepper leaf (Piper auritum Kunth) & “papalo” (Porophyllum ruderale) were obtained using a stirring or an ultrasound extraction system with five types of solvents (water, 50:50% v/v ethanol: water, 70:30% v/v ethanol: water, 85:15% v/v ethanol:1.5 N HCl, & ethanol). Total phenolic compounds and antioxidant activity were evaluated with the phenol Folin Ciocalteu reagent and the ABTS method, respectively.

   • According to Condé-Hernandez LA (2017)

     Excerpt Essential oils (EO) of Piper auritum (“hoja santa”) & Porophyllum ruderale (“pápalo” or “pápalo quelite”), previously dried, were obtained by supercritical extraction (SCE) with CO2. P auritum oil yields were in the range 2.37 ± 0.05–3.09 ± 0.12 g oil/100 g dry material & in P ruderale the yields were 0.82 ± 0.01–1.35 ± 0.09 g oil/100 g dry material.

   • According to Dzigbor A (2025)

     Excerpt Dzigbor A et al, total phenolic content, antioxidant activity, GC-MS characterization, & antimicrobial activity of leaf & flower extracts of Porophyllum ruderale, Pharmacol Res-Nat prod, 7-100243, 2025-Abstract:.

2. 2

   Central pain, hyperalgesia,

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • Excerpt According to Author (1996) — excerpt:

   • According to traditional medicine several properties like cicatrizant, antiseptic, antiinflamatory, antispasmodic, analgesic are attributed to the plant Porophyllum ruderale, besides others. ln addition, we had the pusposes to study the effect of the PR etanolic extract over the contortions number induced by prostacic1in & acetic acid as imtant agents yvhen is injected intraperitoneally doses like 130, 260, 400 & 550 mg/kg of the extracts as wellas over termical sensivity inhibition with central analgesy test Tail-flick using doses of 150, 300, 350, 400 & 500 mg/kg, and in Hot-plate with doses of 150, 300, 350, 400 and 500 mg/kg

     Excerpt The phytochemical- analysis-.of PR showed the presence of the following constituents: essencial oils, carotenoids, fatty acids, alkaloids, flavonic aglycones, cOUI~arins, tannin Sc, tlavonoids, anthocyanids, steroidal saponins.

   • According to Lima G (2011)

     Excerpt The present work investigated the antinociceptive & antiinflammatory activities of the Porophyllum ruderale aqueous extract (PRAE). Taken together, our results suggest that the PRAE can constitute target potential for use in thérapies of the pain & inflammation.

3. 3

   Wound, burn

   Plant part used: Sheet. Mentioned synergistic association: Laser Ingap-670.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Jâcomo AC (2015)

     Excerpt In this study, we investigated the effects of an extract of the leaves of Porophyllum ruderale & laser irradiation on the healing of burns. ruderale & laser irradiation.

   • According to Vasquez-Atanacio MJ (2021)

     Excerpt These studies were carried on the extracts & isolated com- pounds and support most of their reported uses in folk medicine as antifungal, antileishmanial, anti-inflammatory, anti-nociceptive & burn repair activities, & as a potential source of new class of insecticides. Plants belong of genus Porophyllum have been used in Mexican traditional medicine to treat kidney & intestinal diseases, parasitic, bacterial, & fungal infections & anti-inflammatory & anti-nociceptive activities.

   • Excerpt According to Author (1996) — excerpt:

   • Excerpt According to traditional medicine several properties like cicatrizant, antiseptic, antiinflamatory, antispasmodic, analgesic are attributed to the plant Porophyllum ruderale, besides others.

   • According to Raggi L (2014)

     Excerpt Porophyllum ruderale (Asteraceae), known as “arnica paulistana”, is used for wound healing, antimicrobial and anti-inflammatory. The present work aims to compare the chemical composition of essential oils from both Porophyllum ruderale subspecies cultivated in two biogeographically different regions, Brazilian Cerrado (Mogi-Guaçu, São Paulo) and Atlantic Rain Forest (Instituto de Botânica, São Paulo) in different phenological stages.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.