Pouteria sapota (Sapôt) : medicinal properties in alcoholic extraction

Pouteria sapota (Sapôt, Sapote) — family Sapotacées.

Scientific synonyms : Bassia jussaei Griseb, Calospermum mammosum-Pierre, C parvum Pierre, Lucuma bonplandii Kunth, Sapota mammosa Mill, Sideroxylon sapota Jacq..

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 23 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 125 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Complications of diabetes: abnormal serum levels: albumin, total protein, creatinine

   Plant part used: stem.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Sathya Prabhu (2017)

     Excerpt The present study focused on the green synthesis of AgNPs from the aqueous leaf extract of Pouteria sapota in order to evaluate the in vitro & in vivo antidiabetic properties of this extract & the synthesized AgNPs. Conclusion: The aqueous leaf extract of PS & AgNPs exhibited efficient antidiabetic activity in the rat model of diabetes & therefore could have potential for development for medical applications in the future.

   • According to KARIE P (2021)

     Excerpt Regardless of its commendable phytoconstituents which could have free radical scavenging potential, this fruit peel is as yet still needed to be assessed for in vitro antidiabetic prospects. Thus, suggesting further studies with isolated phytochemicals from peel to explore its potentials for antidiabetic activity through in vitro α-glucosidase enzyme inhibition.

   • According to Prabhu S (2018)

     Excerpt Prabhu S et al, Evaluation of antidiabetic activity of biologically synthesized silver nanoparticles using Pouteria sapota in streptozotocin‐induced diabetic rats Jl of Diabetes, 2018;10(1):43.

2. 2

   Type II diabetes mellitus

   Plant part used: stem.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Sathya Prabhu (2017)

     Excerpt The present study focused on the green synthesis of AgNPs from the aqueous leaf extract of Pouteria sapota in order to evaluate the in vitro & in vivo antidiabetic properties of this extract & the synthesized AgNPs. Conclusion: The aqueous leaf extract of PS & AgNPs exhibited efficient antidiabetic activity in the rat model of diabetes & therefore could have potential for development for medical applications in the future.

   • According to KARIE P (2021)

     Excerpt Regardless of its commendable phytoconstituents which could have free radical scavenging potential, this fruit peel is as yet still needed to be assessed for in vitro antidiabetic prospects. Thus, suggesting further studies with isolated phytochemicals from peel to explore its potentials for antidiabetic activity through in vitro α-glucosidase enzyme inhibition.

   • According to Prabhu S (2018)

     Excerpt Prabhu S et al, Evaluation of antidiabetic activity of biologically synthesized silver nanoparticles using Pouteria sapota in streptozotocin‐induced diabetic rats Jl of Diabetes, 2018;10(1):43.

3. 3

   Cancer: adjuvant treatment of colorectal, squamous cell, breast and lung cancer

   Plant part used: stem.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Kamalakannan K (2016)

     Excerpt The MTT assay results for 24 hrs & 72 hrs incubation of Quercetin & EPS at the concentrations 1000,500,250,125 & 62.5% showed increased Breast cancer (MCF-7) cell viability as the concentration got diluted. The isolation of organic compound from Pouteria sapota was subjected to column chromatographic separation analysis.

   • According to Sathya PG (2018)

     Excerpt The results of the study showed that aqueous extract of the P.sapota leaf was rich in phytochemicals, antioxidant activity & showed a significant anti-cancer activity against tested MCF-7 cell lines. Further, the aqueous leaf extract was screened for cytotoxic activity against breast cancer cell lines (MCF-7) in vitro.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.