Saraca asoca (Ashoka) : medicinal properties in alcoholic extraction

Saraca asoca (Ashoka) — family Caesalpiniacées.

Scientific synonyms : Jonesia asoca Roxb., J confusa Hassk, J pinnata Willd, Saraca confusa (Hassk.) Backer, S indica sensu Bedd., non L..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 8 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 81 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Polycystic ovary syndrome: abnormalities in serum parameters associated with PCOS: testosterone, LH (luteinising hormone), insulin, and malondialdehyde, elevated levels of FSH (follicle-stimulating hormone), oestradiol, progesterone, prolactin, SD (superoxide dismutase), glutathione and catalase; low levels

   Plant part used: Trunk bark.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ahmad F (2016)

     Excerpt Saraca asoca bark has been used in the Ayurvedic system of medicine for female urino-genital disorders. Pinitol is a well-known bioactive compound for a variety of biological activities, including hypoglycemic & anti-inflammatory activities.

   • According to Chandrakant P (2021)

     Excerpt Saraca asoca was reported to be comprising phytoconstituents, such as Flavonoids, Steroids, Glycosides, Saponins, Carbohydrates, Proteins as well as many Pharmacologic activities such as anti-diabetic, CNS depressant, anti-helminthic, cardio protective, anti-bacterial, anti-menorrhagic, anti-hyperglycaemic & anti-oxidant activities, anticancer activities. Ashoka, also known as Saraca asoca (Roxb.) Wilde, is an indigenous plant that belongs to the Caesalpiniaceae subfamily of the Legume.

   • According to Salvi S (2022)

     Excerpt Formulations containing these componentscan efficiently exert anti-microbial, anti-inflammatory, antimenorrhagia, antidiabetic, anthelmintic,& analgesic activity. Saraca asocabelonging to the family Caesalpinaceae, is popularly known as Ashoka d is a valuable indigenous plant of traditional &pharmacological significance.

   • According to Kumar S (2012)

     Excerpt Other biochemical parameters such as serum cholesterol, triglycerides, HDL-cholesterol, VLDL-cholesterol, LDL-cholesterol, urea, creatinin & proteins levels were also measured at the end of study. All the extracts also improved other altered biochemical parameters associated with diabetes.

   • According to Prathapan A (2012)

     Excerpt The present study investigated the antioxidant, antiglycation & inhibitory potential of flavonoid fraction of Saraca Ashoka flowers (SAF) against alpha-glucosidase & alpha-amylase (the enzymes linked to type 2 diabetes) & LDL oxidation. Conclusions: The overall results demonstrate that SAF can be used as an ideal natural remedy for preventing oxidative stress & other complications associated with diabetes.

2. 2

   Type II diabetes mellitus

   Plant part used: Trunk bark.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ahmad F (2016)

     Excerpt Saraca asoca bark has been used in the Ayurvedic system of medicine for female urino-genital disorders. Pinitol is a well-known bioactive compound for a variety of biological activities, including hypoglycemic & anti-inflammatory activities.

   • According to Chandrakant P (2021)

     Excerpt Saraca asoca was reported to be comprising phytoconstituents, such as Flavonoids, Steroids, Glycosides, Saponins, Carbohydrates, Proteins as well as many Pharmacologic activities such as anti-diabetic, CNS depressant, anti-helminthic, cardio protective, anti-bacterial, anti-menorrhagic, anti-hyperglycaemic & anti-oxidant activities, anticancer activities. Ashoka, also known as Saraca asoca (Roxb.) Wilde, is an indigenous plant that belongs to the Caesalpiniaceae subfamily of the Legume.

   • According to Salvi S (2022)

     Excerpt Formulations containing these componentscan efficiently exert anti-microbial, anti-inflammatory, antimenorrhagia, antidiabetic, anthelmintic,& analgesic activity. Saraca asocabelonging to the family Caesalpinaceae, is popularly known as Ashoka d is a valuable indigenous plant of traditional &pharmacological significance.

   • According to Kumar S (2012)

     Excerpt To investigate the antihyperglycemic & antioxidant properties of the petroleum Ether, chloroform & methanol extract of Saraca asoca leaves in mice. Methods: Swiss albino mice were made diabetic by a single dose of streptozotocin (150 mg/kg i.p.).

   • According to Prathapan A (2012)

     Excerpt The present study investigated the antioxidant, antiglycation & inhibitory potential of flavonoid fraction of Saraca Ashoka flowers (SAF) against alpha-glucosidase & alpha-amylase (the enzymes linked to type 2 diabetes) & LDL oxidation. Conclusions: The overall results demonstrate that SAF can be used as an ideal natural remedy for preventing oxidative stress & other complications associated with diabetes.

3. 3

   Cancer: adjuvant treatment of prostate and lung cancer

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Choudhary A (2021)

     Excerpt Wild or Saraca indica is one of the most ancient trees of India Aim: Aim of this study: is to investigate the anti-cancer effects of SA flower ethanolic extract on prostate cancer cell line. Materials & Methods: The anti-cancer effects of SA extract on prostate cancer cell lines was assessed by cell viability assay, cell & nuclear morphological studies.

   • According to Roy A (2021)

     Excerpt The DAPI staining results showed increased apoptotic cells with condensed chromatin & nuclear fragmentation in ETOH extract of SA flower treatment in lung cancer cells. The cell viability assay clearly showed that the extract of SA flower treatment has significantly reduced the lung cancer cell viability in a dose dependent manner.

   • According to Dharshini A (2021)

     Excerpt The present study shows ethanolic extract of SA flower treatment inhibits cell growth & induces the apoptosis in lung cancer cells. asoca flower treatment in lung cancer cells.

   • According to Diya DA (2021)

     Excerpt The DAPI staining results showed increased apoptotic cells with condensed chromatin & nuclear fragmentation in ethanolic extract of SA flower treatment in lung cancer cells. The present study shows ethanolic extract of SA flower treatment inhibits cell growth & induces the apoptosis in lung cancer cells.

   • According to Cibin T (2012)

     Excerpt The present study investigates the chemopreventive property of flavonoids from Saraca asoca (flowers) on 2-stage skin carcinogenesis in mice models. Saraca asoca (Family Caesalpiniaceae) has been widely used in traditional Indian medicine especially due to its wound-healing property.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.