Sesbania grandiflora (Plant-like hummingbird) : medicinal properties in alcoholic extraction

Sesbania grandiflora (Plant-like hummingbird, Butterfly-flower, Kolibri véjétal, Flè-papiyon, Colibri vegetal, Fleur-papillon) — family Fabacées.

Scientific synonyms : Aechynomene grandiflora-(L)-L., Agati grandiflora- (L)-Desv., A. grandiflora-Desv, Coronilla grandiflora-(L)-Willd, Robinia grandiflora-L., Sesban grandiflorus-Poir..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 19 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 93 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Kumar R (2015)

     Excerpt Sesbania grandiflora flower has been used in folk medicine of India & Nepal for the treatment of diabetes mellitus. Materials & Methods: Antidiabetic activity was screened in alloxan induced diabetic rats at dose of 250 mg/kg and 500 mg/kg of the 70% alcoholic extract of flower for 28 days per orally.

   • According to Tissera Bathini (2020)

     Excerpt grandiflora through LC-HRMS dereplication analysis, followed by isolation, identification and quantification of the major secondary metabolites with potential a-amylase and a glucosidase inhibitory effect as the potential anti-diabetic mechanism. One of its folk medicinal uses is the alleviation or treatment of Type 2 Diabetes mellitus (T2DM).

   • According to Sangeetha A (2015)

     Excerpt In the present study an attempt has been made to evaluate the antidiabetic & antioxidant nature of Sesbania grandiflora leaves. Diabetes was induced by single intraperitoneal injection of streptozotocin (45mg/Kg b.

   • According to Prasanna G (2013)

     Excerpt Prasanna G et al, the therapeutic role of Sesbania grandiflora as an inhibitor of Advanced Glycation End product (AGE) formation & the discovery of lead compounds for managing hyperglycaemia, Planta Med 2013; 79-PN84-DOI: 10.1055/s-0033-135242,.

   • According to Zamroni A (2017)

     Excerpt Zamroni A et al, Antihyperglycemic effect of Sesbania grandiflora seed decoction on streptozotocin-induced diabetic mice: Inflammatory status and the role of interleukin-10, AIP Conference Proceedings 1844, 020015, 2017.

2. 2

   Liver disease: normalisation of serum parameters (SGOT, SGPT, ALP, TP, TB)

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Das ML (2015)

     Excerpt Flower extract of Sesbania grandiflora is used to Heal wrinkles, sight weakness and also promoting vision. These three flowers are Moringa oleifera, Sesbania grandiflora & Squash blossoms.

   • According to Kale I (2012)

     Excerpt Results: The ethanolic and aqueous extract of Sesbania grandiflora (Linn) flower significantly (P<0.001) decreases the biochemical parameters (SGOT, SGPT, ALP, TP, and TB). Methods : The ethanolic and aqueous extract of Sesbania grandiflora (Linn) flower are screened for its hepatoprotective activity in CCl4 (0.5 ml/kg, i.p) induced liver damage in Swiss albino rats at a dose of 200 mg/kg bw.

   • According to Padmalochana K (2015)

     Excerpt This present investigation was aimed to assessing the hepatoprotective activity of aqueous, ethanol and acetone extract of Sesbania grandiflora leaves against carbon tetra chloride (CCl4) induced liver damage in albino rats. The activity was assessed by comparing the biochemical parameters in serum levels such as serum glutamate pyruvate transaminase, serum glutamate oxalate transaminase, total bilirubin, alkaline phosphatase of plant extracts treated group with carbon tetrachloride treated animals.

   • According to Pari L (2003)

     Excerpt Sesbania grandiflora, commonly known as 'Sesbania', is widely used in Indian folk medicine for the treatment of liver disorders. The increased level of serum enzymes (aspartate transaminase, alanine transaminase, alkaline phosphatase), bilirubin, cholesterol, triglycerides, phospholipids, free fatty acids, plasma Thiobarbituric acid reactive substances and hydroperoxides observed in rats treated with erythromycin Estolate were significantly decreased in rats treated concomitantly with Sesbania extract and erythromycin Estolate.

   • According to Prafulla R Tathe (2010)

     Excerpt Prafulla R Tathe et al, Hepatoprotective Activity of Fruit Extract of Sesbania Grandiflora- Pers, Pharmacologyonline 3: 423-430 (2010).

3. 3

   Hepatitis, cirrhosis: normalisation of serum parameters (SGOT, SGPT, ALP, TP, TB), erythromycin-induced liver toxicity

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Pari L (2003)

     Excerpt The increased level of serum enzymes (aspartate transaminase, alanine transaminase, alkaline phosphatase), bilirubin, cholesterol, triglycerides, phospholipids, free fatty acids, plasma Thiobarbituric acid reactive substances and hydroperoxides observed in rats treated with erythromycin Estolate were significantly decreased in rats treated concomitantly with Sesbania extract and erythromycin Estolate. grandiflora leaves (200 mg/kg/day) for 15 days produced significant Hepatoprotection against Erythromycin Estolate (800 mg/kg/day)-induced hepatotoxicity in rats.

   • According to Das ML (2015)

     Excerpt oleifera is very important for medicinal value such as Hepatoprotective, anti-inflammatory, hysteria, lower of serum cholesterol, phospholipid, Triglyceride etc. Flower extract of Sesbania grandiflora is used to Heal wrinkles, sight weakness and also promoting vision.

   • According to Padmalochana K (2015)

     Excerpt This present investigation was aimed to assessing the hepatoprotective activity of aqueous, ethanol and acetone extract of Sesbania grandiflora leaves against carbon tetra chloride (CCl4) induced liver damage in albino rats. The activity was assessed by comparing the biochemical parameters in serum levels such as serum glutamate pyruvate transaminase, serum glutamate oxalate transaminase, total bilirubin, alkaline phosphatase of plant extracts treated group with carbon tetrachloride treated animals.

   • According to Kale I (2012)

     Excerpt Results: The ethanolic and aqueous extract of Sesbania grandiflora (Linn) flower significantly (P<0.001) decreases the biochemical parameters (SGOT, SGPT, ALP, TP, and TB). Methods : The ethanolic and aqueous extract of Sesbania grandiflora (Linn) flower are screened for its hepatoprotective activity in CCl4 (0.5 ml/kg, i.p) induced liver damage in Swiss albino rats at a dose of 200 mg/kg bw.

   • According to Prafulla R Tathe (2010)

     Excerpt Prafulla R Tathe et al, Hepatoprotective Activity of Fruit Extract of Sesbania Grandiflora- Pers, Pharmacologyonline 3: 423-430 (2010).

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.