Sida acuta (Balié-wonzè) : medicinal properties in alcoholic extraction

Sida acuta (Balié-wonzè, Eleven o’clock broom, Balai de onze heures) — family Malvacées.

Scientific synonyms : Malvastrum carpinifolium (L.f.) A.Gray, Malvinda carpinifolium (L.f.) Medik., Sida balbisiana DC., S berlandieri Turcz., S bodinieri Gand., S carpinifolia L. f..

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 22 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 80 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Okwuosa CN (2011)

     Excerpt The effect of the aqueous & methanol extracts of Sida acuta on blood glucose levels in both normal and diabetic rabbits was studied. The positive control drug (Glibenclamide, 0.5 mg/kg body weight, p.o) produced significant reduction on glycemia at 2 hours post glucose load (p<0.01).

   • According to Shankar P (2021)

     Excerpt Conclusion: Sida acuta can be used for the management & treatment of various diseases & disorders. Sida acuta is known as common wireweed, and has a pantropical distribution.

   • According to DINLAKANONT N. (2020)

     Excerpt This study aimed to investigate the in vitro inhibitory activities of alpha-glucosidase and alpha-amylase of three Malvaceous weeds i.e., Sida acuta Burm.

   • According to Tene Tchehegbe O (2017)

     Excerpt Various parts of Sida acuta have been reported in many studies to be used by indigenous people from tropical countries to manage some health problems: rheumatic affections, azoospermia, oligospermia & spermatorrhea, leucorrhoea, wounds, sciatica, nervous & heart diseases, cold, cough, asthma, tuberculosis & respiratory diseases, disorders of the blood, bile & liver, elephantiasis, hemorrhoids, ulcers, gastric disorders & abdominal pain, headache, fever & malaria, skin diseases, worms, diarrhea & dysentery, venereal diseases, renal inflammation, toothache & snake bites. SA has been scientifically studied for its numerous pharmacological profiles such as: antioxidant, antimicrobial & antibacterial, antimalarial, cardiovascular, antiulcer, analgesic & anti-inflammatory, antipyretic, hepatoprotective, hypoglycemic, insecticidal & anticancer.

2. 2

   Bacterial infection: opportunistic infection caused by Staphylococcus aureus in HIV-positive patients, Bacillus subtilis, Staphylococcus aureus, Staphylococcus faecalis, Escherichia coli, and Proteus vulgaris

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Vijaya KR (2008)

     Excerpt All the extracts showed significant inhibitory activity against gram positive bacteria (Bacillus subtilis, Staphylococcus aureus), gram negative bacteria (Escherichia coli, & Proteus vulgaris), fungi (Candida albicans & Aspergillus niger) & clinical isolates of Staphylococcus faecalis, Staphylococcus aureus & some gram-positive bacteria. The antimicrobial activity of 90% ethanol, methanol, ethyl acetate & aqueous extracts of leaves of Sida acuta was investigated to verify its claimed ethno medicinal use as an antimicrobial agent & comparative study of different extracts was carried out.

   • According to Ekpo MA (2009)

     Excerpt The test isolates from human skin infections were Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Escherichia coli, Scopulariopsis candida, Aspergillus niger & Aspergillus fumigatus. The antimicrobial effect of the ethanolic & aqueous extracts of Sida acuta was investigated.

   • According to Iroha IR (2009)

     Excerpt Antimicrobial activity of aqueous & ethanol leaves extracts of Sida acuta against 45 clinical isolates of Staphylococcus aureus isolated from nasal cavity of Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) patients from University of Nigeria teaching hospital, Enugu was evaluated using agar well diffusion method. In addition to authenticating, the folkloric use of SA in the treatment of common diseases, the finding of this study highlights the possible usefulness of this plant material in the treatment of opportunistic infections caused by S.

   • According to Hassan M (2022)

     Excerpt The present study is designed to determine the phytochemical constituents in Sida acuta & their antibacterial effects on pathogenic bacterial species of Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa & Bacillus subtilis. Furthermore, the antibacterial activity of the leaf extract against the bacterial pathogens were assessed using agar well diffusion & broth dilution methods, at varying concentrations of the extract (37.50, 75, 150 & 300 mg/ml), and using Commercially obtained ciprofloxacin as control.

   • According to Smanthong N (2022)

     Excerpt Proteus mirabilis is a significant cause of urinary tract infection that may contribute to struvite stones. Therefore, we investigated the effects of the SA leaf ethanolic extract (SAEE) on growth & on virulent factors (swarming motility and urease activity) of Proteus mirabilis isolated from kidney stone formers.

3. 3

   High blood pressure, fluid retention, oedema

   Plant part used: Root.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Shankar P (2021)

     Excerpt Conclusion: Sida acuta can be used for the management & treatment of various diseases & disorders. Anti-Inflammatory reaction is the ability of a substance to reduce swelling or inflammation.

   • According to Sharma V (n.d.)

     Excerpt Sharma V et al, Anti-Inflammatory & Analgesic Activity of Methanolic Extract of Whole Plant of Sida acuta PharmaTutor,.

   • According to Tene Tchehegbe O (2017)

     Excerpt Various parts of Sida acuta have been reported in many studies to be used by indigenous people from tropical countries to manage some health problems: rheumatic affections, azoospermia, oligospermia & spermatorrhea, leucorrhoea, wounds, sciatica, nervous & heart diseases, cold, cough, asthma, tuberculosis & respiratory diseases, disorders of the blood, bile & liver, elephantiasis, hemorrhoids, ulcers, gastric disorders & abdominal pain, headache, fever & malaria, skin diseases, worms, diarrhea & dysentery, venereal diseases, renal inflammation, toothache & snake bites. SA has been scientifically studied for its numerous pharmacological profiles such as: antioxidant, antimicrobial & antibacterial, antimalarial, cardiovascular, antiulcer, analgesic & anti-inflammatory, antipyretic, hepatoprotective, hypoglycemic, insecticidal & anticancer.

   • According to Malairajan P (2005)

     Excerpt In the present study of some of the Indian medicinal plants Sida acuta whole plant (Malvaceae), Stylosanthes fructicosa (whole plant) (Papilionaceae), Toona ciliata (heart wood) (Meliaceae), Bougainvillea spectabilis (leaves) (Nyctaginaceae), Ficus glomerata (bark, leaves) (Moraceae) & Polyalthia longifolia (leaves) (Annonaceae). The different plants were used in folklore medicine in the treatment of toothache & strengthening of gums, anthelmintic, kidney diseases, analgesic, anti-inflammatory, hepatoprotective, antihyperglycaemic, antihyperglycaemic & anticancer.

   • According to Enemor V (2013)

     Excerpt Ethanol extract of Sida acuta leaves was administered to Wistar albino rats to monitor the effects of the plant components on some organ function parameters including creatinine, urea & bilirubin, as well as some physiologically important electrolytes. However, notwithstanding that SA extract may not impair liver & kidney functions, possible effects on fluid & electrolyte balance should be seriously monitored.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.