Sida cordifolia (Balié-pwéli) : medicinal properties in alcoholic extraction

Sida cordifolia (Balié-pwéli, Balié-savann, Hairy broom, Savannah broom, Balai poilu, Balai-à-savane) — family Malvacées.

Scientific synonyms : Abutilon ramosum G.Don, Sida altheifolia Sw., Sida cordifolia var. altheifolia (Sw.) Griseb., Sida densiflora Domin, Sida rotundifolia Lam. ex Cav. Sida vellozoana Steud..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 17 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 29 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for hepatocellular carcinoma

   Plant part used: Whole plant.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Mallikarjuna G (2013)

     Excerpt The present study was aimed at evaluating the ethanolic extract of whole plant of sida cordifolia L against AFB1 induced HCC. Hepatocellular carcinoma is the fourth common cancer globally occurring by many factors such as mycotoxins, chemicals, genetical, viral factors etc.

   • According to Rejitha S (2012)

     Excerpt Sida cordifolia Linn. has a potent hepatoprotective action against alcohol-induced toxicity, which was mediated by lowering oxidative stress & by down-regulating the transcription factors.

   • According to Rao KS (1997)

     Excerpt Rao KS et al, Isolation & assessment of hepatoprotective activity of fumaric acid obtained for the first time from Sida cordifolia.

   • According to Kotoky J (2001)

     Excerpt Kotoky J et al, Hepatoprotective activity of Sida cordifolia roots against carbon tetrachloride intoxicated rats.

   • According to Bhutkar PM (2024)

     Excerpt Its extract was found to possess effective antitumor activity in hepatocellular carcinoma & HeLa cell lines. Sida cordifolia of the family Malvaceae is widely used in traditional medicine for treating inflammation, respiratory & neurological ailments & wound healing.

2. 2

   Diabetic nephropathy

   Plant part used: Aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Imran M (2023)

     Excerpt Sida cordifolia & Sida rhombifolia are regarded as useful herbs as they have been shown to be effective, inexpensive and harmless in the prevention of diabetes, and are recognized as valuable therapeutic substances. SC may be further explored for the treatment of diabetic nephropathy &, due to its diverse nature, may be utilized for the treatment of a wide range of diseases, as it provided more significant findings.

   • According to Diwan PV (1999)

     Excerpt Sida cordifolia extracts of the aerial & root parts showed good analgesic, antiinflammatory & hypoglycaemic activities. The ethyl acetate extract of both root & aerial parts of SC (SCR‐E & SCA‐E) showed very good central & peripheral analgesic activities at a dose of 600 mg/kg.

   • According to Ahmad M (2013)

     Excerpt The present study was aimed to evaluate the hypoglycemic, anti-hyperlipidemic & antioxidant potential of alcoholic-extract obtained from areal part of SC in streptozotocin-induced-diabetes in wistar-rats. Thus, the findings of the present study indicate that the alcoholic extract of SC at dosage level of 400 mg/kg produces anti-diabetic effect in the streptozotocin-induced diabetes in Wistar-rats.

3. 3

   Liver toxicity caused by aflatoxin B1

   Plant part used: Whole plant.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Mallikarjuna G (2013)

     Excerpt The present study was aimed at evaluating the ethanolic extract of whole plant of sida cordifolia L against AFB1 induced HCC. Hepatocellular carcinoma is the fourth common cancer globally occurring by many factors such as mycotoxins, chemicals, genetical, viral factors etc.

   • According to Rejitha S (2012)

     Excerpt has a potent hepatoprotective action against alcohol-induced toxicity, which was mediated by lowering oxidative stress & by down-regulating the transcription factors. We studied the hepatoprotective activity of 50 % ethanolic extract of SC roots against alcohol intoxication.

   • According to Rao KS (1997)

     Excerpt Rao KS et al, Isolation & assessment of hepatoprotective activity of fumaric acid obtained for the first time from Sida cordifolia.

   • According to Kotoky J (2001)

     Excerpt Kotoky J et al, Hepatoprotective activity of Sida cordifolia roots against carbon tetrachloride intoxicated rats.

   • According to Dhalwal K (2005)

     Excerpt The comparative anti- oxidant potential of ethanol extracts of Sida cordifolia leaf, stem, root, & whole plant was studied. All extracts of Sida cordifolia (SC) have effective reducing power & free- radical scavenging activity.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.