Sonchus oleraceus (Léti-savann’) : medicinal properties in alcoholic extraction

Sonchus oleraceus (Léti-savann’, Zèb-lapen, Savannah lettuce, Rabbit grass, Laitue-de-savane, Herbe-à-lapin) — family Asteracées.

Scientific synonyms : Sonchus ciliatus Lam., S mairei H. Lev., S sundaicus Blume, Hieracium oleracerum Linn., Lactuca oleracerea Linn..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 13 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 45 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Liver disorders in people with diabetes: normalisation of serum parameters, hepatitis, cirrhosis, fatty liver, fever

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Chen L (2019)

     Excerpt oleraceus (SOL) on Streptozotocin (STZ)-induced diabetic rats. oleraceus daily for 6 weeks showed significantly decreased levels of tumor necrosis factor alpha & interleukin-1β in the liver.

   • According to Teugwa CM (2010)

     Excerpt The present study aims at evaluating the antioxidant & antidiabetic potential of methanol & hydroethanol extracts of the stem bark & leaves of Pricralima nitida & the Sonchus oleraceus whole plant respectively. The antidiabetic activity was tested in mice following streptozotocin diabetes induction, & selected oxidative stress markers (Malondialdehyde, Hydrogen peroxides & Catalase) were measured in order to evaluate the level of oxidative stress in treated animals.

   • According to Aissani F (2022)

     Excerpt Sonchus oleraceus is a Mediterranean leafy vegetable. The aerial parts are widely used in Algerian traditional medicine to treat several diseases such as inflammation, hepatitis, and for detoxication.

   • According to Mohasib RMM (2021)

     Excerpt The result showed that pronounced cytotoxic activity of cancer cells at 100 μg/ml in aqueous fraction in breast cancer (94.8%), while in Methanol extract in Colon Carcinoma (88%) On the other hand, ethyl acetate fraction of the SO showed the highest percentage of colon cancer cells (82.6%) & breast cancer (80%), while the ethyl acetate extract in hepatocellular carcinoma cell line showed moderate effect (46.3%). This study aims to evaluate the successive extraction of the active ingredients & their anticancer activity of arial parts (stem, leaves & flowers) of Sonchus oleaceous.

   • According to Hussein M (2014)

     Excerpt extracts (ethanolic & aqueous) were evaluated for hepatoprotective activity against liver toxicity induced by paracetamol. Sonchus oleraceus L.

2. 2

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Chen L (2019)

     Excerpt oleraceus (SOL) on Streptozotocin (STZ)-induced diabetic rats. Sonchus oleraceus Linn.

   • According to Teugwa CM (2010)

     Excerpt The present study aims at evaluating the antioxidant & antidiabetic potential of methanol & hydroethanol extracts of the stem bark & leaves of Pricralima nitida & the Sonchus oleraceus whole plant respectively. The antidiabetic activity was tested in mice following streptozotocin diabetes induction, & selected oxidative stress markers (Malondialdehyde, Hydrogen peroxides & Catalase) were measured in order to evaluate the level of oxidative stress in treated animals.

3. 3

   Cancer: adjuvant treatment for breast cancer

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Zgair ZE (2010)

     Excerpt This study was designed to evaluate the anticancer, effects of the ethanolic (EE), cold aqueous (CAE), & hot aqueous (HAE) extracts of Sonchus oleraceus on cancer cell lines (in vitro). In vitro study was performed on three cancer cell lines (murine mammary adenocarcinoma AMN-3 cell line, laryngeal carcinoma Hep-2 cell line) & rat embryogenic fibroblast (REF) as normal cell line.

   • According to Mohasib RMM (2021)

     Excerpt The result showed that pronounced cytotoxic activity of cancer cells at 100 μg/ml in aqueous fraction in breast cancer (94.8%), while in Methanol extract in Colon Carcinoma (88%) On the other hand, ethyl acetate fraction of the SO showed the highest percentage of colon cancer cells (82.6%) & breast cancer (80%), while the ethyl acetate extract in hepatocellular carcinoma cell line showed moderate effect (46.3%). This study aims to evaluate the successive extraction of the active ingredients & their anticancer activity of arial parts (stem, leaves & flowers) of Sonchus oleaceous.

   • According to Chen L (2019)

     Excerpt oleraceus daily for 6 weeks showed significantly decreased levels of tumor necrosis factor alpha & interleukin-1β in the liver. Sonchus oleraceus Linn.

   • According to Yin J (2007)

     Excerpt This study investigated in vitro antioxidant activity of Sonchus oleraceus by extraction solvent, which were examined by reducing power, hydroxyl radical-scavenging activity (HRSA) & 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assays. The cytotoxic activity showed that EtOH extract had the best activity against the growth of stomach cancer cell.

   • According to Huyan T (2016)

     Excerpt Anti-tumor effect of hot aqueous extracts from Sonchus oleraceus (L.) L.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.