Spathodea campanulata (Gabon tulip tree) : medicinal properties in alcoholic extraction

Spathodea campanulata (Gabon tulip tree, Tulipier du Gabon) — family Bignoniacées.

Scientific synonyms : Spathodea Nilotica-Seem.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 11 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 40 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Bacterial infection: Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, Pseudomonas spp., Salmonella Typhimurium, Bacillus subtilis, Staphylococcus aureus, Vibrio cholerae

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to KOWTI R (2010)

     Excerpt The ethanol extract of leaf and flower of Spathodea campanulata was investigated for antimicrobial activity at 10 mg/ml concentrations by using Kirby-Bauer disc diffusion method against gram positive and gram negative organisms like Escherichia coli, Klebsiella pneumonia, Proteus vulgaris, Pseudomonas sp, Salmonella Typhimurium, Bacillus subtilis, Staphylococcus aureus, Vibrio cholera. From the dose-dependent study it was observed that the ethanol flower extract was more potent than leaf extract.

   • According to Ayyappa Das MP (2009)

     Excerpt Ayyappa Das MP et al, in vitro anti-bacterial activity of Spathodea Campanulata against Bovine Under isolated bacterial pathogens from dairy herbs.

   • According to Ofori-Kwakye K (2011)

     Excerpt The antibacterial activity of the aqueous, ethanol, methanol and petroleum ether Soxhlet extracts of Sun dried stem bark of Spathodea campanulata P. campanulata (20 % w/w) into aqueous cream, soft paraffin, emulsifying ointment and simple ointment bases and evaluated for their in vitro antimicrobial efficacy.

   • According to Ofori-Kwakye (2009)

     Excerpt he antibacterial activity of the aqueous, ethanol, methanol and petroleum ether Soxhlet extracts of sundried stem bark of Spathodea campanulata P. campanulata (20 % w/w) into aqueous cream, soft paraffin, emulsifying ointment & simple ointment bases & evaluated for their in vitro antimicrobial efficacy.

   • According to Rangasamy D (2008)

     Excerpt Rangasamy D et al, In vitro Phytochemical Screening and Antibacterial Activity of Organic Leaf Extracts of Spathodea campanulata P. Beauv against Hospital Isolated Bacterial Strains, Ethnobotanical Leaflets 12: 1022-28.

2. 2

   Cancer: adjuvant treatment for breast cancer

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Dhanabalan R (2014)

     Excerpt Four plant species Solanum trilobatum, Spathodea campanulata, Syzygium jambos and Tylophora indica leaf extracts extracted with aqueous, methanol, ethanol & chloroform were screened for their anticancer activity in MCF7 cells. The SJELE & STCLE displayed antiproliferative effect of 74.8% & 71% with IC50 concentrations 132.53 µg/mL &203.23 µg/mL respectively.

3. 3

   Kidney failure (damage to the nephrons caused by paracetamol)

   Plant part used: Bark.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Abubakker S (2012)

     Excerpt Abubakker S et al, Protective Effect of Spathodea Campanulata Bark against Paracetamol-Induced Nephrotoxicity in Rats, Inter J of Pharm Tech Res, 1(4) :398-403, 2012-The results of the present investigation Illustrated that ethanolic extract of the plant produced significant protection over paracetamol-induced alterations in serum marker enzymes and cellular damage. Combined effect of active principles present in the ethanolic extract of Spathodea campanulata might offer protection against renal damage rendered by paracetamol in rats.

   • According to Shanmukha (2010)

     Excerpt Shanmukha et al, ANTIOXIDANT AND NEPHROPROTECTIVE ACTIVITY OF SPATHODEA CAMPANULATA BARK AGAINST GENTAMICIN INDUCED NEPHROTOXICITY, Pharmacologyonline 1: 666-675, 2010.

   • According to Ansah C (2013)

     Excerpt The objective of the present study was to evaluate the hepatoprotective and curative potential of the aqueous extract of the stem bark of Spathodea Campanulata (SCE) in a carbon tetrachloride-induced model of hepatotoxicity in rats. The present study thus suggests that aqueous stem bark extract of S campanulata significantly reverses CCl4hepatic damage in rat.

   • According to Coolborn F (2012)

     Excerpt The safety use of the ethanol extract of Spathodea campanulata leaf was evaluated using Swiss albino mice.

   • According to KOWTI R (n.d.)

     Excerpt Ethanol extract of Spathodea campanulata leaves showed significant dose dependent antioxidant activity, with a direct relationship between activity and concentration of extract. The present study is to investigate the antioxidant activity of ethanol extract of Spathodea campanulata leaves in different model systems.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.