Stachytarpheta cayennensis (Vèvèn-Karayib) : medicinal properties in alcoholic extraction

Stachytarpheta cayennensis (Vèvèn-Karayib, Vèvèn-Latjérat, Caribbean verbena, Rat’s-tail verbena, verveine Caraïbe, Verveine-Queue-à-rat) — family TRAMIL.

Scientific synonyms : Abena cayennensis-(Rich)-Hitch, Lippia cylindrica-Scheele, Stachytarpheta australis-Moldencke, Verbena Cayennensis-Rich, V dichotoma-R & P, Zappania cayennensis-(Rich)-Mirb..

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 12 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 27 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type 1 diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Adebayo AC (2007)

     Excerpt This active butanol fraction was subjected to chromatographic subfractionation; some subfractions reduced hyperglycaemia in alloxan-diabetic rats to 60 and 78% & induced insulin release from the INS-1 cells; other subfractions, however, gave hyperglycaemic activities IN VIVO & inhibition of insulin release from the INS-1 cells. o.) of aqueous (125 mg/kg) & methanolic (2000 mg/kg) extracts of the leaves to alloxan-diabetic rats showed significant blood glucose reductions by 43 & 53%, respectively, at the end of a 4 hour period similar to the strong effect of glibenclamide (5 mg/kg, P.

   • According to Eliakim-Ikechukwu C (2009)

     Excerpt Groups B & D received daily oral doses of 250mg/kgb.w of Stachytarpheta cayennensis aqueous ethanolic leaf extract.This study aimed at validating the traditional claims of hypoglycaemic effect of the herb lasted for 21 days & thereafter the remaining rats were sacrificed & the liver dissected out for histological studies. Type 1 Diabetes mellitus was induced in groups B & D by a single intraperitoneal dose of 65mg/kgbw of streptozotocin.

   • According to Olayode AC (2019)

     Excerpt The many pharmacological potentials of Stachytarpheta cayennensis (L.C. Rich) Vahl, especially in managing central nervous system disorders, hypertension, diabetes & infections, have made it a subject of abuse, necessitating the need to ascertain its safety.

2. 2

   Cancer: adjuvant treatment for ductal pancreatic carcinoma

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Adebesin OA (2016)

     Excerpt This study investigated the antiproliferative attributes of hydroethanolic & aqueous leaf extracts of Stachytarpheta cayennensis on human pancreatic carcinoma cell lines (AsPC-1). There is an urgent need for agents with improved efficacy against pancreatic cancer, as only 20% of pancreatic cancer patients undergoing chemotherapy respond to treatment.

   • According to Author (2021)

     Excerpt In the present study, we described the novel usage of Stachytarpheta cayennensis ediated copper nanoparticles & its anti-cancer activity in both in vitro & in vivo model of skin cancer. Also, the anti-cancer potential of Cu-NPs was evaluated in A375 cells.

   • According to Onofre SS (2015)

     Excerpt The objective of this work was therefore to detect variations in total phenol & flavonoid content, & in the antioxidant activity of samples of Stachytarpheta cayennensis. In recent years, a substantial amount of evidence has pointed to the key role of free radicals & other oxidants as the main culprits for aging & degenerative diseases associated with aging, such as cancer, cardiovascular diseases, cataract, decline of the immune system & brain dysfunctions.

3. 3

   Osteoarthritis, arthritis, rheumatism, oedema

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to PENIDO C (2006)

     Excerpt In the present work, the anti-inflammatory & gastroprotective properties of ethanolic extracts of Stachytarpheta cayennesis (L.C. Overall, these data provide evidence for the anti-inflammatory & gastroprotective properties of SC, supporting its use in folk medicine for such purposes.

   • According to Sulaiman MR (2009)

     Excerpt The present study was carried out to explore the antinociceptive as well as the anti-inflammatory effects of an ethanol extract of Stachytarpheta jamaicensis (L.) Vahl (EESJ) using 3 models of nociception & 2 models of inflammation in experimental animals. For antinociceptive effects, 3 models were used: acetic acid-induced abdominal writhing, hot-plate- & formalin-induced paw-licking tests; for anti-inflammatory effects, 2 models were used--carrageenan-induced paw edema & cotton-pellet-induced granuloma tests.

   • According to OKOYE CT (2014)

     Excerpt (Verbenaceae) have been reported to possess potent anti-inflammatory & anti-malarial activities. The leaves of Stachytarpheta cayennensis C.

   • According to Agampodi V (2022)

     Excerpt Plant extracts (6.25-100 μg/mL) & individual compounds (3.125-50 μg/mL) elicited strong anti-inflammatory effects by suppressing the expression of interleukin-8 & inhibiting cyclooxygenase-1 and 5-lipoxygenase enzymes. Anti-inflammatory effects of plant extracts and isolated compounds were evaluated by flow cytometry and cyclooxygenase and lipoxygenase enzyme inhibition assays.

   • According to SCHAPOVAL EE (1998)

     Excerpt The alcoholic & n-butanolic extracts of dried leaves of Stachytarpheta cayennensis (L.C. The compounds also showed in vivo antiinflammatory activity when administered orally to rats mainly in the fourth hour after the administration of the phlogistic agent (70.22% & 93.99%, respectively).

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.