Stachytarpheta jamaicensis (Vèvèn-Karayib) : medicinal properties in alcoholic extraction

Stachytarpheta jamaicensis (Vèvèn-Karayib, Latjé-rat, Caribbean verbena, Rat’s tail, Verveine caraïbe, Queue de rat) — family Verbenacées.

Scientific synonyms : Aena jamaicensis (L.) Hitchc., Stachytarpheta bogoriensis Zoll. & Moritzi, S indica var. jamaicensis (L.) Razi, S mexicana-Steud, S surinamensis-M ex Pulle, S villosa-T, Valerianoides jamaicense-(L)-M, Verbena jamaïcensis-L, Vermicularia decurrens-M, Zapania jamaïcensis-(L)-Lam.

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 12 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 68 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Liver disorders: hepatitis, cirrhosis, normalisation of serum parameters: bilirubin, SGOT, SGPT, ALP

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Joshi VG (2010)

     Excerpt Ethanolic extract of SJ produced reduction in CCl4 induced elevated levels of SGPT, SGOT, SALP and Serum bilirubin & reversed total protein in rats indicating hepatoprotective activity at the dose of 200mg/kg body weight & was comparable to that of standard drug Liv-52(1ml/kg body weight).Further histopathological studies indicated that the animals pretreated with ethanolic extract of SJ was minimal with distinct preservation of structures & architectural frame of the hepatic cells, &dis comparable to standard Liv-52. Hepatoprotective activity of Ethanolic extract of SJ was evaluated by carbon tetrachloride induced toxicity with standard hepatoprotective drug as Liv-52.

   • According to Ogie-Odia E.A (2009)

     Excerpt From the results obtained, it would appear that SJ does not cause large variations in body weights (p>0.05) but causes a few changes in the liver of albino rats which is not significantly different (p>0.05) from that of the control group. The results obtained showed slight variation in the agility, food intake & physical appearances of the rats with mild congestion, fatty changes & necrosis in the liver.

   • According to Thiagarajan (2018)

     Excerpt To examine the protective effects of SJ on liver &xkidney of LPS-induced endotoxemia in ICR mice via determination of lipid peroxidation & histology assessment. Stachytarpheta jamaicensis (SJ) is one of the plants that being used as alternative in traditional treatments that possess medicinal properties.

   • According to Ataman JE (2006)

     Excerpt The toxicity of powdered Stachytarpheta jamaicensis (L.) Vahl. The results obtained showed slight variation on the physical signs/body appearance of the animals & mild histopathlogic 1esions such as congestion, fatty changes & necrosis in selective tissues such as the liver, blood vessels, kidney, lung & testis but the brain, eyes, intestines (small and large) & heart tissues were essentially normal.

   • According to Idu M (2021)

     Excerpt This study evaluates the anti-diabetic effect of ethanol extract of Stachytarpheta jamaicensis leaf on streptozotocin (STZ) - induced diabetic rats fed on high-fat diet (HFD). Significant (p < 0.05) reductions in activities of serum AST, ALP, total protei& bilirubin were noticed in the groups in contrast to the control.

2. 2

   Diabetic ulcer

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Pandian C (2013)

     Excerpt The aim of the current study was to evaluate the wound healing effect of hydroalcoholic leaf extract of Stachytarpheta jamaïcensis (HLS) on Streptozotocin-induced diabetic rats. The HLS afforded significant wound healing potential in diabetic rats which may be due to the presence of phytochemical constituents such as flavanoids, triterpènes, sterols.

   • According to Wan Rozianoor M. H (2014)

     Excerpt The aim of this study was to determine the hypoglycemic & antioxidant activities of Stachytarpheta jamaicensis ethanolic leaves extract.

   • According to Idu M (2021)

     Excerpt This study evaluates the anti-diabetic effect of ethanol extract of Stachytarpheta jamaicensis leaf on streptozotocin (STZ) - induced diabetic rats fed on high-fat diet (HFD). Then the animals were fasted overnight; hyperglycemic state was induced using reduced dose of streptozotocin (35 mg/kg) & animals were randomly divided into five groups (n = 7); group A received the HFD + STZ (35 mg/kg i.p.); group B received HFD + STZ + gliberclamide (10 mg/kg; i.p); groups C, D & E were administered the HFD + streptozotocin with different doses of the ethanol extract (30, 35 & 100 mg/kg p.o., respectively).

   • According to Ataman JE (2006)

     Excerpt The toxicity of powdered Stachytarpheta jamaicensis (L.) Vahl. leaves, known for treating different ailments such as diabetes, hypertension & bacterial infections in some Nigerian communities, was investigated in rats.

   • According to Ikewuch CJ (2010)

     Excerpt These results suggest the use of SJ tea in the management of dyslipidemia whether primary or secondary to obesity, diabetes mellitus & hypertension, & by extension, the reduction of the risk of cardiovascular diseases. The effects of Stachytarpheta jamaicensis tea on the plasma lipid profile & atherogenic indices were investigated in rabbits.

3. 3

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Wan Rozianoor M. H (2014)

     Excerpt The aim of this study was to determine the hypoglycemic & antioxidant activities of Stachytarpheta jamaicensis ethanolic leaves extract.

   • According to Pandian C (2013)

     Excerpt The aim of the current study was to evaluate the wound healing effect of hydroalcoholic leaf extract of Stachytarpheta jamaïcensis (HLS) on Streptozotocin-induced diabetic rats. The HLS afforded significant wound healing potential in diabetic rats which may be due to the presence of phytochemical constituents such as flavanoids, triterpènes, sterols.

   • According to Idu M (2021)

     Excerpt This study evaluates the anti-diabetic effect of ethanol extract of Stachytarpheta jamaicensis leaf on streptozotocin (STZ) - induced diabetic rats fed on high-fat diet (HFD). Then the animals were fasted overnight; hyperglycemic state was induced using reduced dose of streptozotocin (35 mg/kg) & animals were randomly divided into five groups (n = 7); group A received the HFD + STZ (35 mg/kg i.p.); group B received HFD + STZ + gliberclamide (10 mg/kg; i.p); groups C, D & E were administered the HFD + streptozotocin with different doses of the ethanol extract (30, 35 & 100 mg/kg p.o., respectively).

   • According to Ataman JE (2006)

     Excerpt The toxicity of powdered Stachytarpheta jamaicensis (L.) Vahl. leaves, known for treating different ailments such as diabetes, hypertension & bacterial infections in some Nigerian communities, was investigated in rats.

   • According to Harini (2022)

     Excerpt Stachytarpheta jamaicensis (L.) Vahl. Ethnomedical survey reveals the use of this plant in diabetes & many other disease conditions.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.