Sysygium samarangense (Water apple) : medicinal properties in alcoholic extraction

Sysygium samarangense (Water apple, Malacca apple, Java apple, -from Java, Ponm dlo, Ponm Malaka, Ponm Java, Pomme d’eau, Pomme de Malacca, -de Java) — family Myrtacées.

Scientific synonyms : Eugenia javanica Lam., E samarangense (Bl) O.Berg., Jambosa javanica (Lam.) K.Schum. & Lauterb, J samarangense (Bl) DC...

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 8 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 78 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for liver, breast, lung and uterine cancer

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Zhang, YJ (2016)

     Excerpt The present work selected three fruits & aimed at studying the effects of Syzygium samarangense, Passiflora edulis & Solanum muricatum on alcohol-induced liver injury in mice. These results strongly suggest that treatment with S samarangense & P edulis could protect liver from the injury of alcohol, while S muricatum could aggravate the damage.

   • According to Prommaouan S (2022)

     Excerpt Therefore, this study explored the effects of the SS fruit extract on a high-cholesterol diet-induced vascular endothelial dysfunction & fatty liver in rats. Wax apple fruit (Syzygium samarangense) is one of the most popular tropical fruits in Asia, & contains several essential nutrients.

   • According to Majumder R (2017)

     Excerpt In this study, crude methanolic extract (MSSL) & organic soluble fractions of Syzygium samarangense leaves were evaluated for antioxidant activity using in vitro & in vivo models.

   • According to Thampi N (2015)

     Excerpt Methods: The methanol extract at different concentrations were tested against A549 human lung cancer cell lines for cell viability or cytotoxicity by MTT assay & the hallmark of the apoptosis was analyzed by DNA fragmentation method. samarangense fruit pulps to understand the mechanism of action in vivo that can make an allowance for developing chemotherapeutic agent against cancer.

   • According to LIEANTO C (2023)

     Excerpt LIEANTO C et al, Bioinformatics Study: Syzygium samarangense Leaves Chalcone Extract as Lung Cancer Proliferation Inhibitor, Bio-Interface Res in Applied Chem, 13:2, 2023-Abstract; Wax apple (Syzygium samarangense) is a plant commonly found in Indonesia with various health benefits, especially leaves. This study identifies chalcone extract potential, a flavonoid active compound group in Ss, as a proliferation inhibitor in lung cancer based on bioinformatics analysis.

2. 2

   Bacterial infection: E. coli, Enterobacter aerogenes, Kocuria rhizophila, Bacillus cereus, Salmonella enterica

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Choironi NA (2018)

     Excerpt The extracts showed effective against Bacillus cereus, Salmonella enterica with MIC (minimum inhibition concentration) value 78 µg/ml & against multi strains of Escherichia coli, Enterobacter aerogenes, Kocuria rhizophila with MIC value 2500 µg/mL, 2500 µg/mL & 156 µg/mL. samarangense leaves were examined for antibacterial activity in vitro using broth microdillution method.

   • According to Madhavi M (2015)

     Excerpt Antimicrobial activity study reveals that gram positive bacterial strains are more sensitive than the gram negative bacteria to all the three types of root extracts. Anti oxidant, anti inflammatory, & anti diabetic activity of these root extracts reveal that methanoilc extracts with flavonoids showed the high antioxidant, anti inflammatory & antimicrobial activity than the aqueous & ETAC extract.

   • According to NHI NTH (2024)

     Excerpt Antibacterial activity, minimum inhibitory concentration (MIC), & minimum bactericidal concentration (MBC) of wax apple leaf extract were examined in Vibrio parahaemolyticus, Vibrio vulnificus, Vibrio alginolyticus, & Vibrio harveyi strains. The results showed that the zones of bacterial inhibition against V parahaemolyticus, V vulnificus, V alginolyticus, & V harveyi were 16.00±0.00 mm, 16.67±0.58 mm, 20.00±0.00 mm, 17.00±0.00 mm, respectively.

   • According to Moneruzzaman, M.K (2015)

     Excerpt Moneruzzaman, M.K et al, Bioactive Constituents, Antioxidant & Antimicrobial Activities of Three Cultivars of Wax Apple (Syzygium samarangense L.) Fruits.

   • According to Sekar M (2017)

     Excerpt The antibacterial activity of the extract & cream in different concentrations were investigated using two gram-positive bacteria (Staphylococcus aureus & Bacillus cereus) two gram-negative bacteria (Escherichia coli & Salmonella enterica) through disc diffusion method. The present study was conducted to formulate & evaluate the anti-acne cream containing Syzygium samarangense fruits extract.

3. 3

   Oral infection, tooth decay, dental plaque: Fusobacterium nucleatum

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Moneruzzaman, M.K (2015)

     Excerpt Moneruzzaman, M.K et al, Bioactive Constituents, Antioxidant & Antimicrobial Activities of Three Cultivars of Wax Apple (Syzygium samarangense L.) Fruits.

   • According to Madhavi M (2015)

     Excerpt Anti oxidant, anti inflammatory, & anti diabetic activity of these root extracts reveal that methanoilc extracts with flavonoids showed the high antioxidant, anti inflammatory & antimicrobial activity than the aqueous & ETAC extract. The present study includes phytochemical screening and quantification of secondary metabolites & their biological activities of root extract of Syzygium samarangense.

   • According to NHI NTH (2024)

     Excerpt Antibacterial activity, minimum inhibitory concentration (MIC), & minimum bactericidal concentration (MBC) of wax apple leaf extract were examined in Vibrio parahaemolyticus, Vibrio vulnificus, Vibrio alginolyticus, & Vibrio harveyi strains. The purpose of this study is to determine the antibacterial activity of wax apple leaf extract (WALE) against several pathogenic Vibrio strains.

   • According to SULTHANA DSG (2024)

     Excerpt The objective of this study was to evaluate the antibacterial efficacy of wax apple (Syzygium samarangense) fruit extracts (aqueous & ethanol) against Porphyromonas gingivalis, Fusobacterium nucleatum, & Aggregatibacter actinomycetemcomitans. nucleatum only by exhibiting MIC at 1.6 µg/ml for aqueous & 0.4 µg/ml for ETOH extract, but no antibacterial activity was shown against P.

   • According to IDRIS NJ (2023)

     Excerpt Thus, this study was carried out to determine the polyphenolic contents (total phenolic & total flavonoid) & biological activities (antioxidant, alpha-glucosidase and antibacterial assay) of ‘Giant Green’ leaves & fruits at different maturity stages. Identically, young leaves also showed a significant effect in antibacterial assay with an inhibition zone increase of 19%, 36%, 32%, and 31% in S.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.