Tectona grandis (Bwa-Tèk) : medicinal properties in alcoholic extraction

Tectona grandis (Bwa-Tèk, Tèk, Teck) — family Verbénacées.

Scientific synonyms : Jatus grandis (L.f.) Kuntze, Tectona grandis f. abludens K & V, T. grandis f. canescens M, T. grandis f. pilosula M, T. grandis f. punctata M, T grandis f. tomentella M, T. theca Lour., Theka grandis (L.f.) Lam..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 23 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 45 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Bark.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ghaisas MM (2010)

     Excerpt In the present study, the Antihyperglycemic and lipid lowering effect of ethanolic extract of bark of Tectona grandis (TG) was evaluated using alloxan induced diabetes in rats. In India, Tectona grandis is traditionally used in the treatment of diabetes mellitus and lipid disorder.

   • According to Ghaisas M (2009)

     Excerpt Conclusion: Hence it can be concluded that T grandis may prove to be effective in the treatment of Type-II Diabetes mellitus owing to its ability to decrease insulin resistance. The bark of Tectona grandis Linn is traditionally used in the treatment of diabetes.

   • According to Varma SB (2010)

     Excerpt Antihyperglycemic activity of Tectona grandis Linn bark extract on alloxan induced diabetes in rats.

   • According to Kale V (2017)

     Excerpt The result indicated that the waste product of TG wood (sawdust) possess good antidiabetic potential & oral solid dosage form can be made available for management of diabete. The preliminary OGTT study was carried out at different dose levels followed by Antidiabetic activity testing was done on STZ induced diabetic rat model.

   • According to Subramaniam R (2011)

     Excerpt Subramaniam R et al, Antidiabetic, Antihyperlipidemic & antioxidant potential of methanol extract of Tectona grandis flowers in streptozotocin induced diabetic rats, Asian J of Trop Med, 4(8):624-31, 2011.

2. 2

   Type II diabetes mellitus

   Plant part used: Wood.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ghaisas MM (2010)

     Excerpt In the present study, the Antihyperglycemic and lipid lowering effect of ethanolic extract of bark of Tectona grandis (TG) was evaluated using alloxan induced diabetes in rats. In India, Tectona grandis is traditionally used in the treatment of diabetes mellitus and lipid disorder.

   • According to Ghaisas M (2009)

     Excerpt Conclusion: Hence it can be concluded that T grandis may prove to be effective in the treatment of Type-II Diabetes mellitus owing to its ability to decrease insulin resistance. The bark of Tectona grandis Linn is traditionally used in the treatment of diabetes.

   • According to Kale V (2017)

     Excerpt The result indicated that the waste product of TG wood (sawdust) possess good antidiabetic potential & oral solid dosage form can be made available for management of diabete. The preliminary OGTT study was carried out at different dose levels followed by Antidiabetic activity testing was done on STZ induced diabetic rat model.

   • According to Subramaniam R (2011)

     Excerpt Subramaniam R et al, Antidiabetic, Antihyperlipidemic & antioxidant potential of methanol extract of Tectona grandis flowers in streptozotocin induced diabetic rats, Asian J of Trop Med, 4(8):624-31, 2011.

   • According to Pooja Vipin S (2011)

     Excerpt Pooja Vipin S et al, Hypoglycemic activity of methanolic extract of Tectona grandis Linn. Root in alloxan induced diabetic rats, J Applied Pharmaceut Sci 2011; 1(04): 106-9.

3. 3

   Cancer: adjuvant treatment for breast cancer

   Plant part used: Shaft.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Prajuabjinda O (2015)

     Excerpt The ethanolic extract of Tectona grandis stem showed the highest cytotoxic activities against human Breast adenocarcinoma (MCF-7), but was less cytotoxic against large cell lung Carcinoma (COR-L23) (IC50 = 3.92 and 7.78 μg/ml, respectively). This compound showed high specific cytotoxicity against human Breast adenocarcinoma (MCF-7), but was less cytotoxic against large cell lung Carcinoma (COR-L23) (IC50 =16.15 and 47.56 μg/ml or 72.67 and 214.00 μM, respectively).

   • According to MENEZES (de) FURTADO C (2012)

     Excerpt The present work aims to evaluate the photodynamic potential of hydro-alcoholic extract from Tectona grandis LF leaves (TGE) & the same extract prepared as the oïl-water Nanoemulsion (TGE-NE) against melanoma B16 F10 cells. Tectona grandis is a genus of tropical hardwood trees in the mint family, Lamiaceae.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.