Terminalia mantaly (Madagascar almond tree) : medicinal properties in alcoholic extraction

Terminalia mantaly (Madagascar almond tree, white benzoin, Amandier de Madagascar, benjoin blanc) — family Combretacées.

Scientific synonyms : ---.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 5 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 21 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Fungal infection: Aspergillus fumigatus, Candida albicans, C. glabrata, C. parapsilosis, Cryptococcus neoformans

   Plant part used: Bark.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Author (2013)

     Excerpt Ces extraits sont testés sur la croissance in vitro de Candida albicans, Aspergillus fumigatus, Cryptococcus neoformans & Trichophyton mentagrophytes. Des 18 fractions obtenues de la chromatographie sur gel de filtration Sephadex G25 de l'extrait T4-2, seules les fractions F8, F9 et F10 regroupées en fraction P présentent la meilleure activité antifongique : - A fumigatus : CMF = 24,37 μg/ml CI50 = 23 μg/ml - C albicans : CMF = 12,1875 μg/ml CI50 = 1 l, 23 μg/ml - C neoformans : CMF= 12,1875 μg/ml CI50 = 5,87 μg/ml - T mentagrophytes : CMF= 6,09375 μg/ml CI50 = 4,75 μg/ml Par ailleurs, un tri phytochimie couplé à des chromatographies sur couche mince et à la chromatographie HPLC révèle que l'activité antifongique de la fraction la plus actives P serait due à des Polyphénols notamment des Phénols et à des Quinones.

   • According to Ngouana TK (2015)

     Excerpt This paper describes results from the screening of bio-guided fractionated extracts alone & combinations of Terminalia catappa, Terminalia mantaly & Monodora tenuifolia harvested in Cameroon. Mycoses caused by Candida & Cryptococcus species, associated with the advent of antifungal drug resistance have emerged as major health problems.

   • According to Tchuente TMA (2017)

     Excerpt Methods: The anti-yeast extract from Terminalia mantaly (Combretaceae) was fractionated and the structures of the isolated compounds established by means of spectroscopic analysis & comparison with literature data. Activity was assessed against Candida albicans, C.

   • According to Zihiri GN (2012)

     Excerpt The results of the anti-fungal activities of aqueous, hydroalcoholic & residual extracts on the growth of Aspergillus fumigates, a fungal pathogen, show that T mantaly water extract is 64 times more active than T. In recent decades, traditional healers in southern region of Côte d’Ivoire prefer to use the bark of Terminalia mantaly instead of those of T.

   • According to Author (2011)

     Excerpt Pour contribuer à la lutte contre les mycoses opportunistes à fortes recrudescences suite à l’avènement du VIH/SIDA, notre équipe de recherche a testé l’action de 10 extraits issu des écorces de Terminalia mantaly H.Perrier (TEKAM1) : 2 extraits totaux (aqueux et hydro-alcoolique), six extraits issus de partition liquide/liquide et 2 extraits issus de dégraissage à l’hexane au Soxhlet. Ces extraits ont été testés sur la croissance in vitro de Candida albicans, une souche très impliquée dans les mycoses opportunistes.

2. 2

   Oxidative stress

   Plant part used: Bark.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Kipré-Gueyraud R (2023)

     Excerpt The neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease & amyotrophic lateral sclerosis are characterized by a significant increase in oxidative stress that can lead to cellular damage to neurons. In recent years, the antioxidant activity of medicinal plants has become important in research against cancer & neurodegenerative diseases.

   • According to Das G (2020)

     Excerpt This current research review aims to update the detailed biological activities, preclinical & clinical studies of various extracts & secondary metabolites from several plant species under the genus Terminalia, along with information on the traditional uses & chemical composition to develop a promising strategy for their potential applications in the form of medicine or use in modern drug formulations for treating diseases like pneumonia, flu, & other types of viral infections or controlling human contagions. Various species of Terminalia genus are used in the form of herbal medicine & formulations, in treatment of diseases, including headache, fever, pneumonia, flu, geriatric, cancer, to improve memory, abdominal & back pain, cough & cold, conjunctivitis, diarrhea, heart disorder, leprosy, sexually transmitted diseases, & urinary tract disorders.

3. 3

   Infection: fungal: Aspergillus niger & Candida albicans

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Author (2013)

     Excerpt Ces extraits sont testés sur la croissance in vitro de Candida albicans, Aspergillus fumigatus, Cryptococcus neoformans & Trichophyton mentagrophytes. Terminalia mantaly H.

   • According to Author (2011)

     Excerpt Pour contribuer à la lutte contre les mycoses opportunistes à fortes recrudescences suite à l’avènement du VIH/SIDA, notre équipe de recherche a testé l’action de 10 extraits issu des écorces de Terminalia mantaly H.Perrier (TEKAM1) : 2 extraits totaux (aqueux et hydro-alcoolique), six extraits issus de partition liquide/liquide et 2 extraits issus de dégraissage à l’hexane au Soxhlet. Ces extraits ont été testés sur la croissance in vitro de Candida albicans, une souche très impliquée dans les mycoses opportunistes.

   • According to Bolou G E-K (2022)

     Excerpt To do so, the hydroalcoholic extracts of Terminalia catappa, T glaucescens, T ivorensis, Terminalia mantaly & T superba, five plant species used in traditional medicine against dermatoses, were tested on the in vitro growth of resistant strains of Candida albicans. Candidiasis is a fungal disease caused by Candida albicans, a yeast that preferentially affects mucous membranes.

   • According to Tchuente TMA (2017)

     Excerpt Methods: The anti-yeast extract from Terminalia mantaly (Combretaceae) was fractionated and the structures of the isolated compounds established by means of spectroscopic analysis & comparison with literature data. Activity was assessed against Candida albicans, C.

   • According to Ngouana TK (2015)

     Excerpt This paper describes results from the screening of bio-guided fractionated extracts alone & combinations of Terminalia catappa, Terminalia mantaly & Monodora tenuifolia harvested in Cameroon. Mycoses caused by Candida & Cryptococcus species, associated with the advent of antifungal drug resistance have emerged as major health problems.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.