Tetradenia riparia (Mountain lavender) : medicinal properties in alcoholic extraction

Tetradenia riparia (Mountain lavender, Blue baby basil, Kanf, Camphor, Lavand-montangn, Ti-Bazilik blé, Lavande de Montagne, Petit basilic bleu, Camphre) — family Lamiacées.

Scientific synonyms : Basilicum myriostachyum( Benth.) Kuntze, Basilicum riparium (Hochst.) Kuntze, Gumira ferruginea (A.Rich.) Kuntze, Iboza riparia (Hochst.) N.E.Br., Moschosma myriostachyum (Benth), Moschosma riparium Hochst., Plectranthus riparius Hochst., Premna ferruginea A.Rich..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 5 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 73 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Osteoarthritis, arthritis, rheumatism, oedema

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ndayambaje M (2025)

     Excerpt inflammation is the pivotal process for immune response & tissue repair Immunomodulatory molecules emerge as key targets for mitigating inflammation Medicinal plants have been used for many years as a source of healing treatment In this context, the hydroalcoholic extract of Moroccan Ammi visnaga & Rwanda native Tetradenia riparia have been studied for their potential effects as anti inflammatory, antioxidant activities, immunomodulatory effects, & impact on chronic inflammation on inflammatory bowel diseases ( The phytochemical characterization of the extract revealed a variety of components, such as phenols, flavonoids, tannins, coumarins, & saponins For AV the total polyphenolic & total flavonoid content were 23 261261±0 06 mg of Gallic acid equivalents ( & 13 256256±0 01 mg of quercetin equivalents ( per gram of dry weight respectively For TR the concentration was 17 6767±0 109 mg GAE & 7 8787±0 233 mg QE In vitro tests demonstrated that the extract possesses antioxidant properties & the ability to scavenge free radicals, including DPPH, ABTS, nitric oxide ( phosphomolybdate, & ferric reducing antioxidant power ( Additionally, the extract was found to inhibit hydrogen peroxide (H 2 O 2 induced hemolysis In vivo study showed that the oral administrations of various doses 0 25 5 g/kg/w) of the TR extract to Wistar rats in single doses for acute toxicity studies or daily for 28 days for sub acute toxicity have shown no toxicity The histological analysis had shown no significant structural damage in the spleen, liver, & kidney LD 50 was 5 g/kg/w In a female Swiss albino mice model of acetic acid in vascular permeability, AV & TR significantly inhibited extravasations of Evans blue at doses of 0 5 & 1 g/kg(p< 0 05 The anti inflammatory activity of the TR extract suppressed the carrageenan induced paw edema swelling with a reduction of white blood cells & inhibition of NO in the air pouch animal model Both AV & TR revealed the effect of attenuating hepatic renal chronic inflammation induced by carrageenan On the other hand, Av extract demonstrated a preventive effect against IBD The extract also demonstrated potential immunomodulatory properties in mice by enhancing antibody production in response to antigens In Silico molecular docking studies of both extracts showed a strong affinity between khellin or visnagin, Luteolin or stigmasterol, & immunomodulatory proteins NF κB p 52 & TNF α, providing a promising starting point for further investigation These findings suggest that AV & TR extract demonstrated anti inflammatory & antioxidant effects with immunomodulatory properties & could serve as therapeutic agents to combat some chronic inflammatory diseases,.

   • According to Ndayambaje M (2025)

     Excerpt This study evaluated its antioxidant, toxicity, & anti-inflammatory effects using in vivo toxicity tests, paw edema, air pouch models, & vascular permeability assessment. Tetradenia riparia (T.

   • According to KHUMALO GP (2024)

     Excerpt The ethanol extracts of M comosus (commonly known as honey flower), Tetradenia riparia (Hochst.) Codd (misty plume bush) & W salutaris (G. This study investigates the anti-inflammatory properties of extracts prepared from the leaves of eight southern African medicinal plants used traditionally to treat inflammation & pain.

   • According to Demarchi IG (2015)

     Excerpt Tetradenia riparia is a plant that is used as a traditional medicine in South Africa to treat inflammatory & infectious diseases.

   • According to Demarchi I (2015)

     Excerpt Tetradenia riparia plant is used as a traditional medicine in Africa for the treatment of inflammatory and infectious diseases as like parasitic.

2. 2

   Bacterial infection: Enterococcus faecalis, Escherichia coli and Staphylococcus aureus

   Plant part used: Root.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Van Puyvelde L (2021)

     Excerpt aureus, Enterococcus faecalis, & Listeria innocua. Tetradenia riparia (commonly known as ginger bush) is frequently used in traditional African medicine to treat foodborne infections including diarrhoea, gastroenteritis, & stomach ache.

   • According to Njau EF (2014)

     Excerpt To evaluate the antibacterial activity of Tetradenia riparia crude extracts against Escherichia coli, Staphylococcus aureus & Enterococcuss faecalis.

   • According to Fernandez ACM (2017)

     Excerpt The FR-IV presented antioxidant potential with 181.67 μg gallic acid/mg, IC50 of 0.61 μg/mL by DPPH method, 55.61% oxidation protection by β-carotene/linoleic acid system and 4.59 µM ferrous sulfate/mg of sample by FRAP, & the FR-I showed higher antibacterial potential on the strain Staphylococcus aureus with MIC 0.98 μg/mL, Enterococcus faecalis & Bacillus cereus with MIC 31.2 μg/mL. Tetradenia riparia (Lamiaceae) is native to Central Africa popularly known as myrrh, used in folk medicine to treat various diseases like malaria, gastroenteritis, & tropical skin disease.

   • According to Mtavangu SG (2022)

     Excerpt In this work, Ag-ZnO nanocomposites were prepared by a green synthesis route using aqueous leaf extract of Tetradenia Riparia & investigated for antibacterial activity against Escherichia coli & Staphylococcus aureus.

   • According to Elaka IK (2020)

     Excerpt All plant extracts exhibited antibacterial activity on Escherichia coli, Pseudomonas aeruginosa & Staphylococcus aureus to varying degrees. C sativa exhibited strong effect on Staphylococcus aureus & Escherichia coli.

3. 3

   Fungal infection: Aspergillus flavus, A. glaucus, Candida albicans and C. tropicalis

   Plant part used: Aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Njau EFA (2017)

     Excerpt Leaf extracts (80% ethanol), tested for antimicrobial & antiviral activity, & was found to hamper the growth of Staphylococcus aureus, Candida albicans, Mycobacterium smegmatis, & Bacillus subtilis. This review intends to give the major highlights of the genus Tetradenia which will stimulate researchers into carrying out further investigations on the various species of the plant that may contribute into pharmacology industry,.

   • According to GAZIM ZC (2010)

     Excerpt The antimicrobial activity of the EO against the bacterial strains: Staphylococcus aureus, Bacillus subtilis, Enterococcus faecalis, Escherichia coli, Salmonella enterica, Pseudomonas aeruginosa, Klebsiella pneumonia, Proteus mirabilis, Morganella morganii, & Enterobacter cloacae, & the pathogenic fungus Candida albicans was assessed by the disc diffusion method & determination of the minimum inhibitory concentration. The seasonal variation of the chemical composition of the essential oil from fresh leaves of Tetradenia riparia (Hochst.) Codd grown in southern Brazil was analyzed by GC-MS, & the analgesic & antimicrobial activities of this oil were assayed.

   • According to Scanavacca J (2022)

     Excerpt Antifungal activity (Rhizopus oryzae, Aspergillus flavus, Aspergillus ochraceus, Penicillium verrucosum & Fusarium graminearum) was performed by broth microdilution & the antimycotoxigenic assay was performed with A. Tetradenia riparia is known for its richness in essential oil which has been widely investigated due to its biological activities such as antimicrobial, insecticidal, trypanocidal, antimalarial & antioxidant.

   • According to KAKANDE T (2019)

     Excerpt This work aimed at determining prevalence of dermatophytosis & antifungal activity of ethanolic crude leaf extract of Tetradenia riparia against dermatophytes isolated from patients attending Kampala International University Teaching Hospital (KIU-TH), Uganda. The prevalence of dermatophytosis was significantly (p=0.001) associated with age groups of participants with higher infection among those aged 11-20 & 21-30 years with 75.0% each.

   • According to De Soura-Terron M (2019)

     Excerpt The anti-Leishmania activity of Tetradenia riparia essential oil (TrEO) & its derivatives, such as the diterpene 6,7-dehydroroyleanone (TrROY), & the immunomodulatory effects of TrEO have been reported. TrROY (0.1 μg/ml) induced a 31% reduction of the rate of infection in murine macrophages compared with untreated cells.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.