Trichosanthes cucumerina (Konkonb-sèpan) : medicinal properties in alcoholic extraction

Trichosanthes cucumerina (Konkonb-sèpan, Snake cucumber, Kikenga, Patola, Vegetable snake, Concombre-serpent, Serpent vegetal) — family Cucurbitacées.

Scientific synonyms : Anguina cucumerina (L.) Kuntze, Cucumis anguinus (L.) L., Involucraria anguina (L.) Roem., Trichosanthes anguina L., T brevibracteata-Kundu, T colubrina J.Jacq., T. cucumerina var. anguina (L.) Haines.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 6 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 40 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: above-ground parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Arawwawala LD (2013)

     Excerpt Materials & Methods: (a) Anti-inflammatory activity was investigated by carrageenan-induced rat paw oedema model, (b) Gastroprotective activity was investigated by absolute ethanol & indomethacin induced ulceration models & (c) Hypoglycemic activity was investigated by measuring the fasting blood glucose levels in normoglycemic rats. Objective: The objective of the present study was to investigate (a) Anti-inflammatory, (b) Gastroprotection & (c) Hypoglycemic activities of T.

   • According to Kirana H (2008)

     Excerpt Materials & Methods: Non-Insulin Dependent Diabetes Mellitus (NIDDM) was induced by administering streptozotocin (90 mg/kg, i.p.) in neonatal rat model. on non-insulin dependent diabetes mellitus induced rats.

   • According to Arawwawala M (2009)

     Excerpt Aerial parts of Trichosanthes cucumerina (Family: Cucurbitaceae) are used in traditional medical systems for treatment of diabetes and other diseases. In STZ-induced diabetic rats, no immediate hypoglycemic effect was observed.

2. 2

   Viræmia: Chikungunya and dengue

   Plant part used: Pest control and veterinary products. Mentioned synergistic association: Vetiveria zizanioïdes, Trichosanthes cucumerina.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Reddy LJ (2010)

     Excerpt Evaluation of antibacterial activity of Trichosanthes Cucumerina L.

   • According to Harit M (1996)

     Excerpt Harit M et al, Antifungal activity of the unsaponifiable fractions of the fixed oils of (Trichosanthes) seeds.

   • According to Seshadri VD (2020)

     Excerpt Plants such as, Vetiveria zizanioïdes, Trichosanthes cucumerina, & Mollugo cerviana were collected from Western Ghats, Tamilnadu, India. zizanioïdes was found to be highly active against E.

   • According to Arawwawala M (2011)

     Excerpt cucumerina extracts exhibited antibacterial activity against gram (+) Ve bacterial strains such as S. cucumerina can exert antibacterial activity.

   • According to Bulbul IJ (2016)

     Excerpt cucumerina showed moderate antibacterial activity with the average zone of inhibition 7-13 mm and 7-9 mm respectively. The main aim of this study was to find out the antibacterial, cytotoxic & antioxidant activities of n-hexane, chloroform & ethyl acetate extracts of T.

3. 3

   Bacterial infection: S. aureus, S. pyogenes, E. coli, P. aeruginosa

   Plant part used: above-ground parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Arawwawala M (2011)

     Excerpt cucumerina aerial parts was evaluated by (a) viable colony count and (b) disc diffusion techniques against gram (+) & gram (–) bacterial strains such as Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli & Pseudomonas aeruginosa. cucumerina extracts exhibited antibacterial activity against gram (+) Ve bacterial strains such as S.

   • According to Seshadri VD (2020)

     Excerpt Plants such as, Vetiveria zizanioïdes, Trichosanthes cucumerina, & Mollugo cerviana were collected from Western Ghats, Tamilnadu, India. These three plants were taken at 1:1:1 ratio & extracted with methanol at 1:10 ratio & synergistic activity was tested against bacterial pathogens.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.