Acalypha hispida (Cat's tail) : medicinal properties in alcoholic extraction

Acalypha hispida (Cat's tail, Latjé-chat, Queue-de-chat) — family Euphorbiacées.

Scientific synonyms : Acalypha sanderi N. E. Br., A sanderi K. Schum. Ricinocarpus hispidus (Burm. f.) Kuntze.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 7 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 45 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to AFFARISI H (2024)

     Excerpt Hence, we aimed to evaluate the antidiabetic effects of AH extract & nanoextract on pancreatic β-cells, insulin secretion, glycogen content, & histone modifications in streptozotocin-induced diabetic rats. In conclusion, AH extract & nanoextract have antidiabetic effects by restoring β-cell number & density & decreasing H3K9 acetylation in the islets of Langerhans in streptozotocin-induced diabetic rats.

   • According to Alfarisi H (2020)

     Excerpt This investigation is aimed at evaluating the polyphenol profile, antioxidant, α-glucosidase & α-amylase inhibitory & the hypoglycemic activities of Acalypha hispida leaf extract in vivo. The extracts were found to have a polyphenol profile (ultraperformance liquid chromatography quadrupole time-of-flight) & to exhibit antioxidant activity (2,2-diphenyl-1-picrylhydrazyl) & α-glucosidase & α-amylase inhibition (spectrophotometer) in vitro & a hypoglycemic effect in vivo.

   • According to SHIRIRAO AV (2025)

     Excerpt Acalypha hispida is a treasure of multiple pharmacological properties & presently leaves of this plant have been explored to evaluate the protective effects against Streptozotocin-induced diabetic neuropathy in rats. Oxidative stress has a key role in the pathogenesis & progress of diabetic peripheral neuropathy (DPN), one of the most common & debilitating complications of diabetes mellitus.

   • According to PRAJNA PP (2022)

     Excerpt Acalypha hispida belongs to the family Euphorbiaceae, it is a tropical shrub & an annual plant commonly known as ‘chenille plant’, ‘Red hot cat tail. AH have been reported to have various pharmacological activities such as anti-inflammatory, anti-oxidant, hypoglycemic, anti-microbial, anti-fungal activity, trypanocidal effect, cytotoxic activities etc.

   • According to SA’DIAH S (2023)

     Excerpt Previous research showed that Acalypha hispida has strong antioxidant activity in vitro & anti-hyperglycemic activity in vivo. The antioxidant content of Cu,Zn-SOD in MET, CAH, NAH3, & NAH6 groups was significantly higher than in the DMC group of the pancreas of diabetic rats.

2. 2

   Diarrhoea

   Plant part used: leaf. Mentioned synergistic association: Acalypha Fructicosa, Acalypha Nervosa.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Manikanta B (2014)

     Excerpt The present study was designed to investigate antidiarrhoeal potential of combined 70% hydro ethanolic extracts of Acalypha hispida, Acalypha nervosa & Acalypha fruiticosa Castor oil introduced diarrhoea in wister rats.phyto chemical screening of the plant extract for their active constituents was also carried out using standard procedures. Oral administration of combibned hydro ethanolic extract of AH, AN & AF & dose dependently delayed the onset of diarrhoea induced by castor oil & also significantly reduced the number of diarrhoeal episodes and number of animals exhibiting diarrhoea.

   • According to PRAJNA PP (2022)

     Excerpt Acalypha hispida belongs to the family Euphorbiaceae, it is a tropical shrub & an annual plant commonly known as ‘chenille plant’, ‘Red hot cat tail. Different part of the plant is also used in infectious diarrhoea, pulmonary problems & as an expectorant in asthma.

3. 3

   Cancer: adjuvant treatment for breast and prostate cancer

   Plant part used: parties aeriennes.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ancy R (2025)

     Excerpt Aim: In this study, the aerial part (stems, leaves & flowers) of Acalypha indica (Family: Euphorbiaceae) was cold-extracted using ethanol solvent, & the anticancer activity was assessed using breast cancer cell line, MDA-MB-231. Conclusion: Thus, this preliminary study indicates that the ETOH-extracted AI aerial parts can be used to treat breast cancer.

   • According to Amarnath K (2014)

     Excerpt The present exploration reports an extensive evaluation of in vitro anticancer efficacy of a novel aqueous ethanolic extract of Acalypha indica (ETAI) loaded chitosan-casein (CS-CT) microparticles in a cancer cell line model. Cytotoxicity, as investigated on human prostate cancer cell line (PC3) by MTT assay, revealed insignificant differences between free ETAI & CS/CT/ETAI microparticles treated cells in the first 24 h, while higher cytotoxicity was demonstrated by CS/CT/ETAI microparticles, following 72 h of incubation.

   • According to Onocha PA (2011)

     Excerpt Antileishmaniasis & phytotoxicity of the methanolic extracts of the stem & leaves of three Nigerian medicinal Acalypha species namely: Acalypha hispida, Acalypha torta & Acalypha wilkesiana was evaluated in vitro, as part of the screening of ethno - medically useful plants from the Nigerian flora as source for bioactive compounds. It has also been observed that bioactive & natural antitumor compounds can inhibit the growth of Lemna minor.

   • According to Author (2016)

     Excerpt Present investigation was performed to investigate anti- inflammatory, antioxidant activity, & quantification of selected bioactive plant polyphenols of the ethanol (EAH) & aqueous (AAH) extracts of Acalypha hispida (Euphorbiaceae) leaves. Inflammation & oxidative stress can lead to different chronic diseases including cancer and atherosclerosis.

   • According to Onocha PA (2011)

     Excerpt The hexane extract of Acalypha hispida (Burn F.) was screened for phytochemical constituents & was found to contain flavonoids, carbohydrates, phenols&d alkaloids. Free radicals are involved in the process of lipid peroxidation & play a cardinal role in numerous chronic diseases like cancer, coronary heart disease & ageing.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.