Adansonia digitata (Baobab) : medicinal properties in alcoholic extraction

Adansonia digitata (Baobab, Monkey bread, Pain de singe) — family Bombacacées.

Scientific synonyms : Adansonia spahaerocarpa – A. Chew, Adansonia Spahaerocarpa-A.Chew.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 11 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 30 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: FRUIT (PULP).

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Author (2017)

     Excerpt In this study, the experiment evidence obtained indicates that ethanolic extract of Adansonia digitata Linn., fruits possess the antidiabetic properties which suggests the presence of Biologically active components which may be Worth further investigation & elucidation. The Antidiabetic activity of extract was accessed by the method of streptozotocin induced diabetes in rats.

   • According to SILVA ML (2023)

     Excerpt Adansonia digitata L. Despite scientific studies revealing that this fruit has a wide diversity of bioactive compounds with beneficial effects on health, there is a gap in the review of information about their mechanisms of action & critical analysis of clinical trials exploring, in particular, their effect on glycemia regulation.

   • According to Yakubu O.E. (2020)

     Excerpt This study was carried out to evaluate the effects of ethanolic leaf extract & stem-back extract of Adansonia digitata (AD) on liver function, haematology & blood glucose level in alloxan-induced diabetic Wistar rats.

   • According to Pamela O (2017)

     Excerpt digitata possess antidiabetic effect on alloxan induced diabetic rats,. This study was carried out to evaluate the anti-diabetic properties of aqueous leaf extract of Adansonia digitata leaf (ALEAD) on blood glucose level.

   • According to Braca A (n.d.)

     Excerpt Adansonia digitata is a tree attracting recent interest especially due to the high nutritional value of the fruit pulp. All fruit pulp extracts exerted antioxidant activity (highest for Fruit 3) & higher α-glucosidase inhibition than acarbose used as standard.

2. 2

   Diarrhoea

   Plant part used: FRUIT (PULP).

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Suleiman M (2014)

     Excerpt Suleiman M et al, Antidiarrhoeal effect of the crude Methanol extract of the dried fruit of Adansonia digitata L. Vet World, 2014; 7(7): 495-500.Acute Toxicity Study: Literature review showed that the acute toxicity study on fruit extracts of Adansonia digitata, was performed & the extract did not produced toxicity till the dose level of 5000 mg/kg.

   • According to Maha Y (2013)

     Excerpt The Antidiarrhoeal activity of ethanolic extract of Adansonia digitata fruit pulp was evaluated in rats. A digitata was orally administered to rats at dose rate of 250 and 500mg/kg and Loperamide was used at 3mg/kg as reference Antidiarrheal drug.

   • According to SILVA ML (2023)

     Excerpt Adansonia digitata L. Ethnopharmacological uses of various plant parts have been reported for hydration, antipyretic, antiparasitic, antitussive, & sudorific properties a also in the treatment of diarrhea dysentery in many African countries.

   • According to Thiagarajan V (2015)

     Excerpt In traditional system of medicine Adansonia digitata the seeds are used for various aliments including antiinflammatory, analgesic, antipyretic activity, antioxidant, Antidiarrhoeal and anti-dysentery & Trypanosomal activity. Thiagarajan V et al, Evaluation of Antiarthritic potential of Adansonia digitata seed extract, Int Jl of Multidisciplinary Res & Development, 2(4) :548-54, 2015-Abstract Adansonia digitata (Baobab) is a large deciduous tree up to 25m in height and may live for more than hundred years.

   • According to UMARU HA (2024)

     Excerpt Adansonia digitata L. The plant parts are used to treat various ailments such as diarrhoea, malaria & microbial infections.

3. 3

   Bacterial infection: Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Staphylococcus

   Plant part used: ECORCE.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to YUSHA’U M (2010)

     Excerpt The extracts were tested for antimicrobial activity against clinical bacterial isolates of Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis & Staphylococcus specie using disc diffusion & microbroth dilution technique. Powdered stem bark of Adansonia digitata was extracted with ethanol & chloroform using percolation method & Soxhlet extractor.

   • According to MATSUETE GT (2025)

     Excerpt Pulmonary infection induced by Klebsiella pneumoniae is becoming one of the leading causes of respiratory infection worldwide. This study aimed to evaluate the in vitro & in vivo antibacterial properties of Adansonia digitata L.

   • According to Kabbashi AS (2014)

     Excerpt Whole plants of Adansonia digitata (leave) & Cucurbita maxima (seed) were extracted by ethanol, with different concentrations (500, 250 & 125 μg/ml) & Metronidazole (312.5 μg/ml) to be investigated against E. maxima (seed) extract showed a moderate antioxidant activity via DPPH assay free radical test, however Adansonia digitata (Leave) extract showed low antioxidant activity through the same test.

   • According to Chinsembu KC (2019)

     Excerpt Among the IC50 values are 0.10 g/ml (Uvaria angolensis), 3 g/ml (Hemidesmus indicus), 2.3 g/ml (Adansonia digitata), 6.24 g/ml (Caesalpinia coriaria), 7.2 g/ml (Terminalia sericea), 17.4 g/ml (Hypoxis hemerocallidea), & 79 g/ml (Moringa oleifera). The chemical diversity & activity profiles of HIV-1 reverse transcriptase inhibitors from plants reveal two recurring motifs: the structure of several active anti-reverse transcriptase compounds mimics nucleoside analogues, & numerous anti-reverse transcriptase phytochemicals have pleiotropic effects & heterogenous pharmacological benefits during infection & disease.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.