Adansonia digitata (Baobab) : vertus médicinales en extraction alcoolique

Adansonia digitata (Baobab, Pain de singe, Monkey bread) — famille Bombacacées.

Synonymes scientifiques : Adansonia Spahaerocarpa-A.Chew, Adansonia spahaerocarpa – A. Chew.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 11 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 30 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : FRUIT (PULPE). Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Auteur (2017)

     Extrait In this study, the experiment evidence obtained indicates that ethanolic extract of Adansonia digitata Linn., fruits possess the antidiabetic properties which suggests the presence of Biologically active components which may be Worth further investigation & elucidation. The Antidiabetic activity of extract was accessed by the method of streptozotocin induced diabetes in rats.

   • Selon SILVA ML (2023)

     Extrait Adansonia digitata L. Despite scientific studies revealing that this fruit has a wide diversity of bioactive compounds with beneficial effects on health, there is a gap in the review of information about their mechanisms of action & critical analysis of clinical trials exploring, in particular, their effect on glycemia regulation. (2020) — extrait : This study was carried out to evaluate the effects of ethanolic leaf extract & stem-back extract of Adansonia digitata (AD) on liver function, haematology & blood glucose level in alloxan-induced diabetic Wistar rats. Conclusion: This study showed that alloxan-induced diabetes mellitus caused a possible liver disease condition & alteration of the haematological indices.

   • Selon Pamela O (2017)

     Extrait digitata possess antidiabetic effect on alloxan induced diabetic rats,. This study was carried out to evaluate the anti-diabetic properties of aqueous leaf extract of Adansonia digitata leaf (ALEAD) on blood glucose level.

   • Selon Braca A (s.d.)

     Extrait Adansonia digitata is a tree attracting recent interest especially due to the high nutritional value of the fruit pulp.

2. 2

   Diarrhée

   Partie usitée : FRUIT (PULPE).

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Suleiman M (2014)

     Extrait Suleiman M et al, Antidiarrhoeal effect of the crude Methanol extract of the dried fruit of Adansonia digitata L. Vet World, 2014; 7(7): 495-500.Acute Toxicity Study: Literature review showed that the acute toxicity study on fruit extracts of Adansonia digitata, was performed & the extract did not produced toxicity till the dose level of 5000 mg/kg.

   • Selon Maha Y (2013)

     Extrait The Antidiarrhoeal activity of ethanolic extract of Adansonia digitata fruit pulp was evaluated in rats. A digitata was orally administered to rats at dose rate of 250 and 500mg/kg and Loperamide was used at 3mg/kg as reference Antidiarrheal drug.

   • Selon SILVA ML (2023)

     Extrait Adansonia digitata L. Ethnopharmacological uses of various plant parts have been reported for hydration, antipyretic, antiparasitic, antitussive, & sudorific properties a also in the treatment of diarrhea dysentery in many African countries.

   • Selon Thiagarajan V (2015)

     Extrait In traditional system of medicine Adansonia digitata the seeds are used for various aliments including antiinflammatory, analgesic, antipyretic activity, antioxidant, Antidiarrhoeal and anti-dysentery & Trypanosomal activity. Thiagarajan V et al, Evaluation of Antiarthritic potential of Adansonia digitata seed extract, Int Jl of Multidisciplinary Res & Development, 2(4) :548-54, 2015-Abstract Adansonia digitata (Baobab) is a large deciduous tree up to 25m in height and may live for more than hundred years.

   • Selon UMARU HA (2024)

     Extrait Adansonia digitata L. The plant parts are used to treat various ailments such as diarrhoea, malaria & microbial infections.

3. 3

   Infection bactérienne : Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Staphylococcus

   Partie usitée : ECORCE.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon YUSHA’U M (2010)

     Extrait The extracts were tested for antimicrobial activity against clinical bacterial isolates of Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis & Staphylococcus specie using disc diffusion & microbroth dilution technique. Powdered stem bark of Adansonia digitata was extracted with ethanol & chloroform using percolation method & Soxhlet extractor.

   • Selon MATSUETE GT (2025)

     Extrait Pulmonary infection induced by Klebsiella pneumoniae is becoming one of the leading causes of respiratory infection worldwide. This study aimed to evaluate the in vitro & in vivo antibacterial properties of Adansonia digitata L.

   • Selon Kabbashi AS (2014)

     Extrait Whole plants of Adansonia digitata (leave) & Cucurbita maxima (seed) were extracted by ethanol, with different concentrations (500, 250 & 125 μg/ml) & Metronidazole (312.5 μg/ml) to be investigated against E. maxima (seed) extract showed a moderate antioxidant activity via DPPH assay free radical test, however Adansonia digitata (Leave) extract showed low antioxidant activity through the same test.

   • Selon Chinsembu KC (2019)

     Extrait Among the IC50 values are 0.10 g/ml (Uvaria angolensis), 3 g/ml (Hemidesmus indicus), 2.3 g/ml (Adansonia digitata), 6.24 g/ml (Caesalpinia coriaria), 7.2 g/ml (Terminalia sericea), 17.4 g/ml (Hypoxis hemerocallidea), & 79 g/ml (Moringa oleifera). The chemical diversity & activity profiles of HIV-1 reverse transcriptase inhibitors from plants reveal two recurring motifs: the structure of several active anti-reverse transcriptase compounds mimics nucleoside analogues, & numerous anti-reverse transcriptase phytochemicals have pleiotropic effects & heterogenous pharmacological benefits during infection & disease.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.