Anacardium occidentale (Nwa-kajou) : medicinal properties in alcoholic extraction

Anacardium occidentale (Nwa-kajou, Cashew nuts, Noix de Cajou) — family Anacardiacées.

Scientific synonyms : Acajuba occidentalis-(L)-Gaertn, Anacardium microcarpum-Ducke, Cassuvium pomiferum-Lam..

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 22 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 82 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Bacterial infection: Streptococcus mutans, Lactobacillus acidophilus, Staphylococcus aureus, MRSA, Enterococcus faecalis, Streptococcus pyogenes, Pseudomonas aeruginosa, Proteus mirabilis, Escherichia coli, Klebsiella pneumoniae, Helicobacter pylori, Salmonella choleraesuis

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Da Silva R.A (2016)

     Excerpt The minimum bactericidal and fungicidal concentrations were determined against: Streptococcus mutans, Lactobacillus acidophilus, Staphylococcus aureus, MRSA, Enterococcus faecalis, Streptococcus pyogenes, Pseudomonas aeruginosa, Proteus mirabilis, Escherichia coli, Klebsiella pneumoniae, Helicobacter Pylori, Salmonella choleraesuis, Candida albicans, & Candida tropicalis. Anacardium occidentale L., Anacardiaceae, is frequently used to treat infections.

   • According to Belonwu DC (2014)

     Excerpt Evaluation of antibacterial activity of different parts of two varieties of Anacardium occidentale{red fruited variety (RFV) & yellow fruited variety (YFV)}, namely, the fruit, leaf, stem bark & root extracts on human pathogens (Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Proteus mirabilis & Klebsiella spp) was carried out in vitro. aeruginosa & Klebsiella spp were inhibited by ethanolic red fruit extract in the following corresponding order: E.

   • According to Kamath K (2017)

     Excerpt Antibacterial activity was carried out by using different concentrations of extracts on bacterial strains of Staphylococcus aureus, Escherichia coli & Pseudomonas aeruginosa by using agar well diffusion method & results were compared. The present study involves comparison of the antibacterial activity of ethanolic extract leaves of Tectona grandis (teak), Mangifera indica (mango), & Anacardium Occidentale (cashew).

   • According to Sudjaroen Y (2018)

     Excerpt Antibacterial activity of CW & CE against Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, & Acinetobacter baumannii were evaluated by resazurin microplate assay (REMA).

   • According to NOR AYSHAH ALIA AH (2016)

     Excerpt Microbial strain-tested were Acinetobacter anitratus, Methicillin-Resistant Staphylococcus aureus (MRSA), Proteus vulgaris, Pseudomonas aeruginosa, S. Therefore, the aim of this study was to evaluate the antimicrobial potencial of essential oil extracted from the shoot of potential cashew (Anacardium occidentale Linn.) clones against clinical human pathogens.

2. 2

   Sepsis in people with diabetes

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Oliveira AS (2019)

     Excerpt Considering the in vitro antimicrobial potential of AO, our aim was to investigate whether the oral treatment with the ethanolic extract of flowers can control bacterial growth & the systemic inflammatory response observed in sepsis induced by cecal ligation & puncture (CLP) of diabetic mice. Patients with sepsis frequently have chronic diseases such as diabetes mellitus.

   • According to Shehu A (2010)

     Excerpt The inner reddish bark of the plant was extracted with ethanol & screened for hypoglycemic activity in a model of alloxan-induced diabetes in rat species. This study investigated the hypoglycemic effect of inner bark extract of Anacardium occidentale Linn.

   • According to Eliakim-Ikechukwu C (2009)

     Excerpt Groups A and B served as the negative and positive control groups respectively and received 500mg/Kgbwt of Anacardium occidentale stembark extract and group D received 5IU of insulin. A single intraperitoneal dose of 65mg/Kgbwt of streptozotocin was used to induce experimental diabetes in rats in groups B, C and D while group A was left nondiabetic.

   • According to Bassey T (2012)

     Excerpt This study was designed to investigate the effect of aqueous ethanolic bark extract of Anacardium Occidentale (Cashew) on the histology of the pancreas of streptozotocin induced diabetic Wistar rats. Streptozotocin was used in the production of diabetic models in groups B, C & D by subcutaneous injection of 65mg/kgbwt after an overnight fast.

   • According to Omodamiro OD (2014)

     Excerpt In conclusion, the ethanolic extract of the leaves of GG & AO possess hypoglycaemic activity in alloxan induced diabetic Wistar albino rat. The hypoglycaemic effect of the ethanolic leaves extracts of both plants were compared with that of diabenese (100mg/kg b.w) of fasted alloxan induced rats, following treatment relatively moderate to high doses of both plants (25, 50, 100, 200mg/kg b.

3. 3

   Type 2 diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Omodamiro OD (2014)

     Excerpt w.) produced a dose-dependent significant reduction (p<0.05) in blood glucose levels of fasted alloxan induced diabetic rat after 1-3 days compared to control. In conclusion, the ethanolic extract of the leaves of GG & AO possess hypoglycaemic activity in alloxan induced diabetic Wistar albino rat.

   • According to JAISWAL YS (2016)

     Excerpt The aim of the current study was to investigate the antidiabetic effects of ethanol extract of leaves of AO on neonatal streptozotocin diabetic rats. At the end of the experimental period of 30 days, reduction in the fasting blood glucose levels, serum insulin, glycated hemoglobin levels, serum lipid parameters, & renal function biomarkers were estimated in the control & treated rats.

   • According to Eliakim-Ikechukwu C (2009)

     Excerpt Groups A and B served as the negative and positive control groups respectively and received 500mg/Kgbwt of Anacardium occidentale stembark extract and group D received 5IU of insulin. A single intraperitoneal dose of 65mg/Kgbwt of streptozotocin was used to induce experimental diabetes in rats in groups B, C and D while group A was left nondiabetic.

   • According to Shehu A (2010)

     Excerpt The inner reddish bark of the plant was extracted with ethanol & screened for hypoglycemic activity in a model of alloxan-induced diabetes in rat species. The alloxan-diabetic rats showed significant reduction in plasma glucose level after treatment with the fractions.

   • According to Olatunji LA (2005)

     Excerpt The antidiabetic activity of the cashew plant (Anacardium occidentale. These results show that chronic oral administration of methanol extract of AO stem-bark at a dose of 200.0 mg/kg body weight may be a safe alternative antihyperglycemic agent that has beneficial effect by improving plasma glucose & lipids in fructose-induced diabetic rats, which is associated with a reduced lipid peroxidation.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.