Bauhinia forficata (Beef shank) : medicinal properties in alcoholic extraction

Bauhinia forficata (Beef shank, Orchid tree, Pat-bèf, Patte de bœuf, Arbre orchidée) — family Caesalpiniacées.

Scientific synonyms : Bauhinia candicans-Benth, B brasiliensis-Vogel.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 6 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 34 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Chaves-Bustos EA (2022)

     Excerpt To determine the hypoglycemic activity, the crude extract was prepared in a suspension & administered (500 mg/kg, i.g.) in previously diabetic mice with STZ (120 mg/kg, i.p.), measuring blood glucose levels every week as well as the animals' body weight for six weeks. The diabetic mice + BF presented hypoglycemic effects in the third week of treatment, perhaps due to its secondary metabolites.

   • According to Damasceno DC (2004)

     Excerpt Bauhinia forficata, commonly known as "paw-of-cow", is widely used in Brazil folk medicine for the treatment of Diabetes mellitus. The diabetic pregnant rats presented hyperglycemia, hyperlipemia, hypertriglyceridemia, hypercholesterolemia, hyperuricemia, decreased determinations of reduced glutathione (GSH) & superoxide dismutase (SOD).

   • According to Santos M (2019)

     Excerpt Several Bauhinia species are widely used in Southern South America in the treatment of infections, pain and several diseases including diabetes. The presence of kaempferitrin, an antidiabetic agent, has been confirmed.

   • According to De Souza C (2004)

     Excerpt The antidiabetic activity of aqueous, ethanolic & hexanic extracts of Bauhinia forficata was investigated in a model of alloxan-induced diabetes in rats. The alloxan-diabetic rats showed significant reductions in plasma glucose, triglycerides, total cholesterol & HDL-cholesterol after treatment with the extracts & Glibenclamide (used as standard) as compared to the diabetic controls.

   • According to BREVET

     Excerpt WO2003011311A1 (n.d.) — excerpt: The present invention relates to a plant extract from Bauhinia species with hypoglycaemic activity, which is characterized in being obtained from a Bauhinia species & to a method for producing the extract & the use of the extract in the treatment of diabetes type 2. Preparation of Bauhinia fortificata dry extract by hydroalcoholic extraction Hydroalcoholic extraction with ethanol 50 (v/v) 1 kg of dry milled leaves of Bauhinia fortificata and 6 L of hydroalcoholic solution 50% (v/v) are put in a glass reaction flask and heated under reflux around 1 hour, with continuously stirring.

2. 2

   Type 1 diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Chaves-Bustos EA (2022)

     Excerpt To determine the hypoglycemic activity, the crude extract was prepared in a suspension & administered (500 mg/kg, i.g.) in previously diabetic mice with STZ (120 mg/kg, i.p.), measuring blood glucose levels every week as well as the animals' body weight for six weeks. The diabetic mice + BF presented hypoglycemic effects in the third week of treatment, perhaps due to its secondary metabolites.

   • According to Damasceno DC (2004)

     Excerpt Bauhinia forficata, commonly known as "paw-of-cow", is widely used in Brazil folk medicine for the treatment of Diabetes mellitus. The diabetic pregnant rats presented hyperglycemia, hyperlipemia, hypertriglyceridemia, hypercholesterolemia, hyperuricemia, decreased determinations of reduced glutathione (GSH) & superoxide dismutase (SOD).

   • According to Santos M (2019)

     Excerpt Several Bauhinia species are widely used in Southern South America in the treatment of infections, pain and several diseases including diabetes. The presence of kaempferitrin, an antidiabetic agent, has been confirmed.

   • According to De Souza C (2004)

     Excerpt The antidiabetic activity of aqueous, ethanolic & hexanic extracts of Bauhinia forficata was investigated in a model of alloxan-induced diabetes in rats. The alloxan-diabetic rats showed significant reductions in plasma glucose, triglycerides, total cholesterol & HDL-cholesterol after treatment with the extracts & Glibenclamide (used as standard) as compared to the diabetic controls.

   • According to BREVET

     Excerpt WO2003011311A1 (n.d.) — excerpt: The present invention relates to a plant extract from Bauhinia species with hypoglycaemic activity, which is characterized in being obtained from a Bauhinia species & to a method for producing the extract & the use of the extract in the treatment of diabetes type 2. Preparation of Bauhinia fortificata dry extract by hydroalcoholic extraction Hydroalcoholic extraction with ethanol 50 (v/v) 1 kg of dry milled leaves of Bauhinia fortificata and 6 L of hydroalcoholic solution 50% (v/v) are put in a glass reaction flask and heated under reflux around 1 hour, with continuously stirring.

3. 3

   Diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Chaves-Bustos EA (2022)

     Excerpt To determine the hypoglycemic activity, the crude extract was prepared in a suspension & administered (500 mg/kg, i.g.) in previously diabetic mice with STZ (120 mg/kg, i.p.), measuring blood glucose levels every week as well as the animals' body weight for six weeks. The diabetic mice + BF presented hypoglycemic effects in the third week of treatment, perhaps due to its secondary metabolites.

   • According to Damasceno DC (2004)

     Excerpt Bauhinia forficata, commonly known as "paw-of-cow", is widely used in Brazil folk medicine for the treatment of Diabetes mellitus. The diabetic pregnant rats presented hyperglycemia, hyperlipemia, hypertriglyceridemia, hypercholesterolemia, hyperuricemia, decreased determinations of reduced glutathione (GSH) & superoxide dismutase (SOD).

   • According to Santos M (2019)

     Excerpt Several Bauhinia species are widely used in Southern South America in the treatment of infections, pain and several diseases including diabetes. The presence of kaempferitrin, an antidiabetic agent, has been confirmed.

   • According to De Souza C (2004)

     Excerpt The antidiabetic activity of aqueous, ethanolic & hexanic extracts of Bauhinia forficata was investigated in a model of alloxan-induced diabetes in rats. The alloxan-diabetic rats showed significant reductions in plasma glucose, triglycerides, total cholesterol & HDL-cholesterol after treatment with the extracts & Glibenclamide (used as standard) as compared to the diabetic controls.

   • According to BREVET

     Excerpt WO2003011311A1 (n.d.) — excerpt: The present invention relates to a plant extract from Bauhinia species with hypoglycaemic activity, which is characterized in being obtained from a Bauhinia species & to a method for producing the extract & the use of the extract in the treatment of diabetes type 2. Preparation of Bauhinia fortificata dry extract by hydroalcoholic extraction Hydroalcoholic extraction with ethanol 50 (v/v) 1 kg of dry milled leaves of Bauhinia fortificata and 6 L of hydroalcoholic solution 50% (v/v) are put in a glass reaction flask and heated under reflux around 1 hour, with continuously stirring.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.