Boerhavia diffusa (Patagon) : medicinal properties in alcoholic extraction

Boerhavia diffusa (Patagon) — family Nyctaginacées.

Scientific synonyms : Boerhavia coccinea-B, B erecta-Gauitr., B procumbens-Roxb, B repens-L.

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 25 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 68 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Root.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Saxena N (2018)

     Excerpt Antidiabetic activity using 100 mg/kg & 200 mg/kg of formulation was studied in streptozotocin induced diabetic albino Wistar rats. A polyherbal formulation was prepared containing herbs reported to have good antidiabetic activity & widely used traditionally in India by the folklore for the treatment of diabetes since ages.

   • According to Singh PK (2011)

     Excerpt The present study evaluates the efficacy of ethanolic extract of Boerhaavia diffusa (BD) administered orally at a dose of 500mg/kg body weight for a period of 30 days to alloxanized diabetic rats & its efficacy compared with the standard hypoglycaemic drug Metformin. Administration of BD not only maintained the ionic balance & renal Na+-K+ ATPase activity but also significantly minimized diabetic hyperglycaemia.

   • According to BHATIA V (2011)

     Excerpt The extracts of the plant B diffusa was tested for oral Hypoglycaemic & antidiabetic activity, by glucose oral tolerance test, alloxan induced & streptozotocin Induced diabetic rats respectively. In alloxan-induced diabetic rats also the maximum percentage reduction in blood glucose levels was found to be in B diffusa methanolic extract.

   • According to Author (2019)

     Excerpt It is used as traditional medicine by indigenous people of many countries in the world for its protective role against inflammation, prostatic hyperplasia, diabetes, cancer, gastrointestinal problems, arthritis etc. Boerhaavia diffusa belonging to family Nyctaginaceae has a wide distribution, occurring on major part of the globe.

   • According to DAS S (2023)

     Excerpt Some of the reported reassuring benefits of their purified forms or even the crude extracts are antidiabetic, antimicrobial, anticancer, antioxidant, anti-inflammatory, hepatoprotective, renoprotective, cardioprotective, antifertility, etc. using its antifungal, antibacterial, anticancer, anti-inflammatory, antidiabetic, hepatoprotective, cardioprotective, renoprotective, antifertility benefits & molecular docking study as search string & keywords.

2. 2

   Infections in farmed fish caused by Aeromonas hydrophila, Flavobacterium branchiophilum, Pseudomonas fluorescens, Edwarsiella tarda and Yersinia ruckeri.

   Plant part used: Other.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Pammi SVN (2014)

     Excerpt They were tested for their antimicrobial activity against five fish bacterial pathogens viz Aeromonas hydrophila, Flavobacterium branchiophilum, Pseudomonas fluorescens, Edwarsiella tarda & Yersinia ruckeri. Among the three solvent extracts tested, ethanol extract of B diffusa showed most significant result when compared to other two plant extract.

   • According to Author (2012)

     Excerpt Keeping in view the tremendous ethno medicinal use of B diffusa it was aimed to Scientifically validate the antimicrobial property of B diffusa whole plant. Some screenings have yielded good result & few of these have proceeded to give active antimicrobial compounds like Polygodial, anethol, himejima, cryptolepine, etc.

   • According to DAS S (2023)

     Excerpt using its antifungal, antibacterial, anticancer, anti-inflammatory, antidiabetic, hepatoprotective, cardioprotective, renoprotective, antifertility benefits & molecular docking study as search string & keywords. Some of the reported reassuring benefits of their purified forms or even the crude extracts are antidiabetic, antimicrobial, anticancer, antioxidant, anti-inflammatory, hepatoprotective, renoprotective, cardioprotective, antifertility, etc.

   • According to Adeyemi A (2008)

     Excerpt Extracts of leaves of Alchornea cordifolia, Boerhavia diffusa & Bridelia micrantha were investigated for antibacterial activity against Helicobacter pylori, Salmonella typhi, Salmonella enteritidis, Shigella flexneri & Entero-haemorrhagic Escherichia coli (EHEC). This indicates that leaf extracts of the three plants are of great potential in treating gastric ulcer & diarrhoea caused by the aforementioned bacteria.

   • According to Ali R (2020)

     Excerpt This article is based on a study in which the antibacterial activity of aqueous, methanolic, ethanolic & acetonic extracts of eight medicinal plants were evaluated by standard disc diffusion method against multidrug resistant Escherichia coli & Salmonella spp. The results have indicated that the ethanolic extract of Boerhaavia diffusa showed maximum zone of inhibition against Escherichia coli, while Asparagus racemosus showed maximum zone of inhibition against Salmonella spp.

3. 3

   Escherichia coli bacterial infection, haemorrhagic diarrhoea

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Adeyemi A (2008)

     Excerpt Extracts of leaves of Alchornea cordifolia, Boerhavia diffusa & Bridelia micrantha were investigated for antibacterial activity against Helicobacter pylori, Salmonella typhi, Salmonella enteritidis, Shigella flexneri & Entero-haemorrhagic Escherichia coli (EHEC). This indicates that leaf extracts of the three plants are of great potential in treating gastric ulcer & diarrhoea caused by the aforementioned bacteria.

   • According to Pammi SVN (2014)

     Excerpt They were tested for their antimicrobial activity against five fish bacterial pathogens viz Aeromonas hydrophila, Flavobacterium branchiophilum, Pseudomonas fluorescens, Edwarsiella tarda & Yersinia ruckeri. Methanol, ethanol & aqueous extracts of Boerhaavia diffusa, Asparagus racemosus & Sida cordifolia plants were prepared & screened for their phytochemical components.

   • According to Author (2012)

     Excerpt Keeping in view the tremendous ethno medicinal use of B diffusa it was aimed to Scientifically validate the antimicrobial property of B diffusa whole plant. Some screenings have yielded good result & few of these have proceeded to give active antimicrobial compounds like Polygodial, anethol, himejima, cryptolepine, etc.

   • According to DAS S (2023)

     Excerpt using its antifungal, antibacterial, anticancer, anti-inflammatory, antidiabetic, hepatoprotective, cardioprotective, renoprotective, antifertility benefits & molecular docking study as search string & keywords. Some of the reported reassuring benefits of their purified forms or even the crude extracts are antidiabetic, antimicrobial, anticancer, antioxidant, anti-inflammatory, hepatoprotective, renoprotective, cardioprotective, antifertility, etc.

   • According to Ali R (2020)

     Excerpt This article is based on a study in which the antibacterial activity of aqueous, methanolic, ethanolic & acetonic extracts of eight medicinal plants were evaluated by standard disc diffusion method against multidrug resistant Escherichia coli & Salmonella spp. The results have indicated that the ethanolic extract of Boerhaavia diffusa showed maximum zone of inhibition against Escherichia coli, while Asparagus racemosus showed maximum zone of inhibition against Salmonella spp.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.