Bursera simarouba (Gonmié-wouj) : medicinal properties in alcoholic extraction

Bursera simarouba (Gonmié-wouj, Red gum tree, Gommier rouge) — family Burséracées.

Scientific synonyms : Bursera gummifera-L, Elaphrium ovalifolium-Schlecht, Pistacia simaruba-L, Terebinthus attenuata-Rose.

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 6 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 27 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Osteoarthritis, rheumatoid arthritis, rheumatism, sciatica, oedema

   Plant part used: Bark.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Preethi S (2020)

     Excerpt In pursuit of new medicinal compounds in traditional medicinal plants growing in America (south, north, central part), Bursera Simaruba is one such potential medicinal tree.

   • According to Zuniga B (2005)

     Excerpt Chemical composition & anti-inflammatory activity of the volatile fractions from the bark of eight Mexican Bursera species. Some volatiles were assayed for anti-inflammatory activity using the TPA-induced ear edema bioassay in mice.

   • According to Acevedo M (2015)

     Excerpt Organic extracts from nine species (eleven populations) of the Bursera genus native to Mexico, were investigated for cytotoxic & anti-inflammatory activities. In vivo anti-inflammatory experiments were conducted through the 12-O-tetradecanoylphorbol-13-acetate (TPA) induced ear edema in mice.

   • According to Nogueira B (2004)

     Excerpt BS (Indio desnudo) using carrageenan-induced paw edema inflammation. The comparison of the anti-inflammatory activity of VIII 29 fraction with the corresponding standard of methyl-beta-peltatin A, suggest that this compound could be one of the active principles involved in the anti-inflammatory activity of BS leave.

2. 2

   High blood pressure, oedema

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Acevedo M (2015)

     Excerpt Organic extracts from nine species (eleven populations) of the Bursera genus native to Mexico, were investigated for cytotoxic & anti-inflammatory activities. In vivo anti-inflammatory experiments were conducted through the 12-O-tetradecanoylphorbol-13-acetate (TPA) induced ear edema in mice.

   • According to Preethi S (2020)

     Excerpt In pursuit of new medicinal compounds in traditional medicinal plants growing in America (south, north, central part), Bursera Simaruba is one such potential medicinal tree.

   • According to Nogueira B (2004)

     Excerpt BS (Indio desnudo) using carrageenan-induced paw edema inflammation. The comparison of the anti-inflammatory activity of VIII 29 fraction with the corresponding standard of methyl-beta-peltatin A, suggest that this compound could be one of the active principles involved in the anti-inflammatory activity of BS leave.

   • According to Zuniga B (2005)

     Excerpt Chemical composition & anti-inflammatory activity of the volatile fractions from the bark of eight Mexican Bursera species. Some volatiles were assayed for anti-inflammatory activity using the TPA-induced ear edema bioassay in mice.

   • According to Carrasco OF (2017)

     Excerpt Vascular reactivity experiments were conducted in rat aortic rings obtained from rats with & without sugar-induced hypertension, a model widely used to study such effects with cardiovascular agents. The blood pressure (BP) & heart rate (HR) were evaluated before & after the extract administration.

3. 3

   Metabolic syndrome, obesity

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Guzman-Hernandez E (2023)

     Excerpt Results: Rats with metabolic syndrome developed obesity, arterial hypertension, dyslipidemia, & kidney damage characterized by proliferative glomerulonephritis, necrosis, and reduced activity of anti-oxidant enzymes. Materials & methods: For induction of metabolic syndrome, 20% fructose was used, & it was administered in the water & food to male Wistar rats for 12 weeks, after administering ethanol extract of BS intragastrically (100 a&200 mg/kg/day) for 6 weeks, blood pressure was determined.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.