Caesalpinia coriaria (Divi-divi) : medicinal properties in alcoholic extraction

Caesalpinia coriaria (Divi-divi) — family Caesalpiniacées.

Scientific synonyms : Caesalpinia coriaria (Jacq.) Willd., Caesalpinia thomaea Spreng., Libidibia coriaria (Jacq.) Schltdl., Poinciana coriaria Jacq..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 14 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 35 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment of liver, prostate and uterine cancer

   Plant part used: Fruit Pod.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Pajaro-Gonzalez Y (2016)

     Excerpt To determine the inhibitory activity of the protein carbonylation & the hepatoprotective effect of ethanol extract of the fruits of Caesalpinia coriaria Jacq (Fabaceae). Free radical oxygen species cause protein carbonylation, an irreversible oxidative damage associated with diseases such as liver injury, diabetes mellitus, arthritis, cancer & Alzheimer.

   • According to Revathi K (2014)

     Excerpt It is apparent that the mode of action & the chemical compound, responsible for anticancer activity of Caesalpinia coriara has not been explored. In this study, it emphasized the fact that all four extracts (acetone, ethyl acetate, ethanol & aqueous) have its own unique Tannin, Quinones, carbohydrates, saponins, flavonoids, glycosides, cardiac glycosides, terpenoids, phenols, coumarins, proteins steroids, anthraquinones, flavonoids, polyphenols & other compounds that contribute to anticancer activity.

   • According to Sanchez-Carranza JN (2017)

     Excerpt coriaria was assayed to determine its antiproliferative activity against PC3 (prostate), Hep3B, & HepG2 (hepatocellular), Ca Ski & HeLa (cervical) human cancer cell lines, as well as the immortalized human hepatocytes cell line IHH as control. The IC 50 were calculated, & the results showed that hepatocellular carcinoma HepG2 (16.5 µ g/mL) & Hep3B (20 µ g/mL) cells were the most sensitive to the WAE extract, while IHH cells, which are nottumor cells (202 µ g/mL), were the less sensitive.

   • According to Sanchez-Llodra FI (2022)

     Excerpt The objective of this research is the phytochemical analysis of methanolic & ethanolic extracts of leaves & fruits of wild Caesalpinia coriaria (Jacq.) from La Guajira, Colombia. Furthermore, the metabolites found may represent a less aggressive alternative for the use of antioxidant, antibacterial, antifungal, anticancer & antiviral molecules.

   • According to Janbandhu SJ (2022)

     Excerpt Ethanol extracts of Cassia bonducella, Cassia alata, Caesalpinia coriaria, Brownea coccinea, Cassia javanica, Cassia siamea, Amherstia nobilis, & Bauhinia acuminata showed anti-diabetic action. Antidiabetic, antiulcer, anticancer, antibacterial, anti-inflammatory, & antirheumatic activity are just some of the pharmacological qualities described for these species, & they have been shown to be effective in ethnomedicinal use.

2. 2

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Janbandhu SJ (2022)

     Excerpt Ethanol extracts of Cassia bonducella, Cassia alata, Caesalpinia coriaria, Brownea coccinea, Cassia javanica, Cassia siamea, Amherstia nobilis, & Bauhinia acuminata showed anti-diabetic action. Antidiabetic, antiulcer, anticancer, antibacterial, anti-inflammatory, & antirheumatic activity are just some of the pharmacological qualities described for these species, & they have been shown to be effective in ethnomedicinal use.

   • According to -Brantner A (2016)

     Excerpt n Asia, medicinal plants are applied for the treatment of many diseases including diabetes mellitus [1]. coriaria (Jacq.) Willd leaves [Fabaceae] were investigated for their antidiabetic activity.

   • According to Pajaro-Gonzalez Y (2016)

     Excerpt To determine the inhibitory activity of the protein carbonylation & the hepatoprotective effect of ethanol extract of the fruits of Caesalpinia coriaria Jacq (Fabaceae). Free radical oxygen species cause protein carbonylation, an irreversible oxidative damage associated with diseases such as liver injury, diabetes mellitus, arthritis, cancer & Alzheimer.

3. 3

   Liver disorders: normalisation of serum parameters: ALT, ALP, etc.

   Plant part used: Fruit Pod.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Pajaro-Gonzalez Y (2016)

     Excerpt To determine the inhibitory activity of the protein carbonylation & the hepatoprotective effect of ethanol extract of the fruits of Caesalpinia coriaria Jacq (Fabaceae). The degree of hepatoprotection was determined by measuring the serum liver enzymes, aspartate aminotransferase (AST) & alanine aminotransferase (ALT) & by histopathological analysis of rat liver.

   • According to Sanchez-Carranza JN (2017)

     Excerpt coriaria was assayed to determine its antiproliferative activity against PC3 (prostate), Hep3B, & HepG2 (hepatocellular), Ca Ski & HeLa (cervical) human cancer cell lines, as well as the immortalized human hepatocytes cell line IHH as control. Caesalpinia coriaria also named cascalote, has been known traditionally in México for having cicatrizing & inflammatory properties.

   • According to -Brantner A (2016)

     Excerpt The sample solution & α-glucosidase were mixed with phosphate buffer solution that contained bovine serum albumin & sodium azide. In this study Bauhinia malabarica (Roxb.) leaves, Caesalpinia pulcherrima (Linn.) Swartz flowers & leaves & C.

   • According to Lokeswari (2011)

     Excerpt Lokeswari et al, ISOLATION OF TANNINS FROM CAESALPINIA CORIARIA & bEFFECT OF PHYSI CAL PARAMETERS Chemistry, 2011-.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.