Cannabis sativa (Kanabis) : medicinal properties in alcoholic extraction

Cannabis sativa (Kanabis, Zèb-la, Cannabis, weed, l’Herbe) — family Cannabinacées.

Scientific synonyms : Canabis americana-P ex W, C chinensis-Del, C ruderalis-J, C sativa var indica-(L)-W, C sativa var sativa.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 5 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 125 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Pain, diabetic neuropathy, allodynia

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Arora A (2017)

     Excerpt The aim of present study was to explore the ameliorative potential of cannabis sativa extract in hyperglycemia-induced neuropathic pain. Diabetes induced neuropathic pain is recognized as one of the most difficult types of pain to treat & conventional analgesics are well known to be partially effective or ineffective.

   • According to Abchir O (2023)

     Excerpt Abchir O et al, Exploration of Cannabis constituents as potential candidates against diabetes mellitus disease using molecular docking, dynamics simulations & ADMET investigations. as potential candidates against diabetes mellitus Dis.

   • According to KHAZALEH AK (2024)

     Excerpt Flavonoids, another cannabis component, demonstrate anti-inflammatory, antioxidant, & neuroprotective properties, particularly relevant to neuro-inflammation. Cannabinoids, pivotal in cannabis's bioactivity, exhibit well-documented analgesic, anti-inflammatory, & neuroprotective effects.

   • According to Apetroaei VT (2097)

     Excerpt Hemp (Cannabis sativa L.) has experienced a significant resurgence in popularity, and global interest in diversifying its use in various industries, including the food industry, is growing. Polyphenols & terpenoids, in particular, present in hemp seeds, provide antimicrobial, antioxidant, and anti-inflammatory properties.

   • According to Apetroaei VT (2024)

     Excerpt Scientific studies have shown that these compounds possess significant antioxidant, antimicrobial, and anti-inflammatory effects, making hemp seeds a promising ingredient for promoting health. The growing demand for plant-based protein and natural food ingredients has further fueled interest in exploring hemp seeds (Cannabis sativa L.) as a sustainable source of and nutrition.

2. 2

   Cancer: adjuvant treatment for pancreatic carcinoma

   Plant part used: Aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Emhemmed F (2022)

     Excerpt As CBD emerged as the molecule responsible for inducing apoptosis in the human pancreatic cancer cell line, a CBD-rich cannabis strain remains attractive for therapeutic applications. Thus, we wished to identify compounds with anticancer activity on human pancreatic tumor cell lines.

   • According to Tariq AL (2012)

     Excerpt The protein content in crude extract of Cannabis sativa L for aqueous extract found 112μg/ml & for acetone extract 160μg/ml. The plant leaves were identified as Cannabis sativa L.

   • According to Rozance J (2021)

     Excerpt Cannabis sativa is one of the oldest medicinal plants used by humans, containing hundreds of bioactive compounds. Our data suggest that CS extracts, when properly prepared, can significantly decrease cancer cell viability while protecting healthy cells from cytotoxic effects.

   • According to Dzierżanowski T (2019)

     Excerpt A relatively favorable adverse effects profile, including no depressive effect on the respiratory system, may make cannabis complement a rather narrow armamentarium that is in the disposition of a palliative care professional. There is evidence to indicate cannabis in the treatment of pain, spasticity, seizures, sleep disorders, nausea & vomiting, & Tourette syndrome.

   • According to LI D (2022)

     Excerpt We used HCC1806 squamous cell carcinoma & demonstrated various degrees of efficiency of the tested extracts, from 66% to 92% of growth inhibition of cancer cells. Cannabis sativa is one of the oldest cultivated plants.

3. 3

   Bacterial infection: Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Enterococcus faecalis

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Naveed M (2014)

     Excerpt This present study has been attempting to determine the antibacterial activity of Cannabis sativa leaf extract to some selective pathogenic bacterial strains such as Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Enterococcus faecalis, Salmonella typhi & Klebsiella by using leaf Ethanol extract & Hot water extract. The leaf of C Sativa exerted pronounced antibacterial activity (24.1mm) against Staphylococcus aureus, (10.3mm) against Pseudomonas aeruginosa, (22.2mm) against Escherichia coli, (18.1mm) against Enterococcus faecalis respectively & inactive against the two strains Salmonella typhi & Klebsiella.

   • According to Appendino G (2008)

     Excerpt Marijuana (Cannabis sativa) has long been known to contain antibacterial cannabinoids, whose potential to address antibiotic resistance has not yet been investigated. All five major cannabinoids (cannabidiol (1b), cannabichromene (2), cannabigerol (3b), Delta (9)-tetrahydrocannabinol (4b), & cannabinol (5)) showed potent activity against a variety of methicillin-resistant Staphylococcus aureus (MRSA) strains of current clinical relevance.

   • According to Apetroaei VT (2024)

     Excerpt The growing demand for plant-based protein and natural food ingredients has further fueled interest in exploring hemp seeds (Cannabis sativa L.) as a sustainable source of and nutrition. Since THC (tetrahydrocannabinol) and CBD (cannabidiol) are found only in traces, hemp seeds can be used in food applications because the psychoactive effects associated with cannabis are avoided.

   • According to Apetroaei VT (2097)

     Excerpt Hemp (Cannabis sativa L.) has experienced a significant resurgence in popularity, and global interest in diversifying its use in various industries, including the food industry, is growing. Polyphenols & terpenoids, in particular, present in hemp seeds, provide antimicrobial, antioxidant, and anti-inflammatory properties.

   • According to Wasim K (1995)

     Excerpt In vitro antimicrobial studies were conducted with aqueous, ethanolic & Petroleum ether extracts of the leaves of Cannabis sativa. The aqueous extract however, did not show any antimicrobial activity.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.