Capsicum annuum (Chilli) : medicinal properties in alcoholic extraction

Capsicum annuum (Chilli, Piman, Piment) — family Solanacées.

Scientific synonyms : Capsicum minimum-Roxb..

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 14 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 46 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Inflammatory pain: stiff neck, dislocation, rheumatism, gout

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Hernandez-Ortega M (2012)

     Excerpt The results suggest that the carotenoids in dried guajillo peppers have significant analgesic & anti-inflammatory benefits & could be useful for pain & inflammation relief. Carotenoids extracted from dried peppers were evaluated for their antioxidant, analgesic, & anti-inflammatory activities.

   • According to Basharat S (2020)

     Excerpt The domesticated species include Capsicum annuum, Capsicum frutescens, & Capsicum chinense. TRPV1 is essential for the reduction of oxidative stress, pain sensations, & inflammation.

   • According to Author (2007)

     Excerpt Cosmetic-grade material may be extracted using hexane, ethanol, or vegetable oil & contain the full range of phytocompounds that are found in the Capsicum annuum or Capsicum frutescens plant (aka red chiles), including Capsaicin. Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, resin, fruit powder, capsicum frutescens extract, fruit extract, resin & capsaicin, Int J Toxicol, 26 Suppl 1 :3-106.2007-Abstract : Capsicum-derived ingredients function as skin-conditioning agents--miscellaneous, external analgesics, flavoring agents, or fragrance components in cosmetics.

   • According to Author (1900)

     Excerpt Capsicum, has been used as anti-inflammatory, anti-diabetic, anti-cancer, antiulcer, anticoagulant, analgesic, anti-arthritis, immunomodulatory, memory enhancing, pain relief, Hypocholesterolaemic, hypolipidemic, hepatoprotective & antimicrobial effects. Capsicum plants belongs to the family Solanaceae & kingdom Plantae, consist of 27 species & approximately 3000 varieties.

   • According to Joseph A (2020)

     Excerpt Despite the promising health beneficial effects (thermogenic, lipolytic, hypo-triglyceridemic, Hypocholesterolemic, anti-inflammatory & anticancer) of capsaicinoids-rich red chili Pepper, commonly known as Cayenne Pepper (Capsicum annuum or Capsicum frutescenss), its consumption at physiologically relevant dosage is always hampered by the pungency & stomach discomforts.

2. 2

   Cancer: adjuvant treatment for colorectal carcinoma and melanoma

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Maksimova V (2016)

     Excerpt The aim of this study was to investigate the effect of capsaicin & ethanolic Capsicum extracts on B104 neuroblastoma cells as a potential anticancer agent. On the other hand, ethanolic Capsicum extracts which contained capsaicin (0.5–2.1mmol/L) did not show any cytotoxic effect.

   • According to GU J (2008)

     Excerpt Antioxidant & antiproliferative activity of Pepper (Capsicum annuum L.) leaves.

   • According to Author (2007)

     Excerpt Cosmetic-grade material may be extracted using hexane, ethanol, or vegetable oil & contain the full range of phytocompounds that are found in the Capsicum annuum or Capsicum frutescens plant (aka red chiles), including Capsaicin. Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, resin, fruit powder, capsicum frutescens extract, fruit extract, resin & capsaicin, Int J Toxicol, 26 Suppl 1 :3-106.2007-Abstract : Capsicum-derived ingredients function as skin-conditioning agents--miscellaneous, external analgesics, flavoring agents, or fragrance components in cosmetics.

   • According to Author (1900)

     Excerpt Capsicum, has been used as anti-inflammatory, anti-diabetic, anti-cancer, antiulcer, anticoagulant, analgesic, anti-arthritis, immunomodulatory, memory enhancing, pain relief, Hypocholesterolaemic, hypolipidemic, hepatoprotective & antimicrobial effects. Capsicum plants belongs to the family Solanaceae & kingdom Plantae, consist of 27 species & approximately 3000 varieties.

   • According to Basharat S (2020)

     Excerpt The domesticated species include Capsicum annuum, Capsicum frutescens, & Capsicum chinense. Capsaicinoids are believed to have strong pharmacological properties that could be used in pain relief, weight reduction, cardiovascular conditions, & cancer prevention besides providing relief in gastrointestinal diseases.

3. 3

   Infection: bacterial: Escherichia coli & Pseudomonas aeruginosa

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Erturk O (2011)

     Excerpt epidermidis) & 2 Gram-negative bacteria (Escherichia coli & Pseudomonas aeruginosa), using agar dilution methods. Eleven ethanolic extracts from spices of Melissa officinalis(FR:FE), Mentha piperita((Se), Laurus nobilis(Fe), Rhus coriaria, Dianthus coryophyllum, Piper nigrum( Se), Capsicum annum (Fr), Juniperus oxycedrus, Erica arborea, Colutea arborescens, & Cuminum cyminum(Fr) collected from various regions of Turkey & local markets were assayed for the in vitro antibacterial activity against 3 Gram-positive (Bacillus subtilis, Staphylococcus aureus & S.

   • According to Al-Fartosy AJM (2013)

     Excerpt The compound showed greater antibacterial activity against gram positive (Staphylococcus aureus, & Streptococcus aureus) bacteria than gram negative (Klebsiella pneumonia, Pseudomonas aeruginosa and, E. The present study was designed to determine the antioxidant, antibacterial & cytotoxicity activities of the flavonoid compound (F1) extracted from Capsicum annum Seeds.

   • According to Izah SC (2019)

     Excerpt minima fruit against some bacterial pathogens (Escherichia coli, Staphylococcus aureus, Bacillus subtilis & Pseudomonas aeruginosa). coli, Staphylococcus aureus, Bacillus subtilis & Pseudomonas aeruginosa was 14.33 mm, 14.33 mm, 12.00mm & 14.00 mm, respectively for the ethanolic extract & 11.67mm, 11.33mm, 10.33mm & 12.00 mm, respectively for crude extract.

   • According to Shayan S, (2013)

     Excerpt Shayan S, et al, Antibacterial & antibiofilm activities of extract Capsicum annuum L on the growth & biofilm formation of common pathogenic strains.

   • According to Shayan S (2013)

     Excerpt Shayan S et al, Antibacterial & antibiofilm activities of extract Capsicum annuum on the growth & biofilm.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.