Cassia fistula (Kas) : medicinal properties in alcoholic extraction

Cassia fistula (Kas, Kanéfis, Kas stick, Kas-Zabitan, Casse, Canéficier, Baton-à-casse, Casse-à-Habitant, Baton-Kas) — family Caesalpiniacées.

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 18 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 37 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Bark.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ali M (2012)

     Excerpt The extract significantly (P<0.05) reduced blood sugar level in alloxan induced diabetic (hyperglycaemic) & glucose induced hyperglycemic (normo-hyperglycaemic) rats orally at 250 mg/kg and 500 mg/kg body weight respectively. The present study was designed to evaluate Antihyperglycemic & analgesic effects of ethanolic extract of Cassia fistula (CF) stem barks in rats and mice, respectively.

   • According to Malpani SN (2010)

     Excerpt Malpani SN et al, Antidiabetic activity of Cassia fistula Linn. Bark in alloxan induced diabetic rats.

   • According to Ayinla (2015)

     Excerpt These findings suggest that ETOH leaves extract of S fistula might improve the diabetic induced disturbances of some haematological parameters, reduces the plasma lipid imbalances & decreases the production of free radicals associated with diabetes. Twenty-four albino rats weighing 120-150 g were divided into 4 experimental groups of six rats each; control, diabetic untreated, diabetic treated with Glibenclamide & diabetic treated with 100 mg/kg b.w of Senna fistula.

   • According to Silawat Narendra (2009)

     Excerpt Silawat Narendra et al, The mechanism of hypoglycemic & antidiabetic action of hydro -alcoholic extract of Cassia fistula Linn in rats.

   • According to Author (1975)

     Excerpt SINGJ KN, hypoglycaemic Activity of Albizzia stipulata, Albizzia moluccana & Cassia fistula Leguminous Seed Diets on Normal Young Rats.

2. 2

   Type II diabetes mellitus

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ali M (2012)

     Excerpt The extract significantly (P<0.05) reduced blood sugar level in alloxan induced diabetic (hyperglycaemic) & glucose induced hyperglycemic (normo-hyperglycaemic) rats orally at 250 mg/kg and 500 mg/kg body weight respectively. The present study was designed to evaluate Antihyperglycemic & analgesic effects of ethanolic extract of Cassia fistula (CF) stem barks in rats and mice, respectively.

   • According to Ayinla (2015)

     Excerpt These findings suggest that ETOH leaves extract of S fistula might improve the diabetic induced disturbances of some haematological parameters, reduces the plasma lipid imbalances & decreases the production of free radicals associated with diabetes. Twenty-four albino rats weighing 120-150 g were divided into 4 experimental groups of six rats each; control, diabetic untreated, diabetic treated with Glibenclamide & diabetic treated with 100 mg/kg b.w of Senna fistula.

   • According to Silawat Narendra (2009)

     Excerpt Silawat Narendra et al, The mechanism of hypoglycemic & antidiabetic action of hydro -alcoholic extract of Cassia fistula Linn in rats.

   • According to Malpani SN (2010)

     Excerpt Malpani SN et al, Antidiabetic activity of Cassia fistula Linn. Bark in alloxan induced diabetic rats.

   • According to Author (1975)

     Excerpt SINGJ KN, hypoglycaemic Activity of Albizzia stipulata, Albizzia moluccana & Cassia fistula Leguminous Seed Diets on Normal Young Rats.

3. 3

   Hepatitis, cirrhosis, fatty liver

   Plant part used: fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Kalantari H (2017)

     Excerpt The protective effect of Cassia fistula fruit extract against liver injury evoked by bromobenzene was confirmed by histological examination as well. In the present study, hepatoprotective effect of Cassia fistula fruit extract was investigated in mice.

   • According to ADNAN JEHANGIR (2010)

     Excerpt The purpose of this study was to assess the effect of ethanolic extract of Cassia fistula leaves in experimentally induced drug hepatitis (DIH) in rodents. In conclusion, high dose of C fistula ethanolic leaves extract (500 mg/kg) body weight showed Hepatoprotection against INH/RIF induced hepatitis in rats showed slight recovery whereas the rats in experimental group D showed a significant recovery.

   • According to Xie Q (2012)

     Excerpt The present study was designed to investigate the hepatoprotective effects of cassia seed ethanol extract (CSE) in carbon tetrachloride (CCl(4))-induced liver injury in mice. Oxidative stress has been recognized as a critical pathogenetic mechanism for the initiation & the progression of hepatic injury in a variety of liver disorders.

   • According to Pradeep K (2010)

     Excerpt Protective effect of Cassia fistula Linn on diethyl nitrosamine induced hepatocellular damage & oxidative stress in ethanol pretreated rats.

   • According to Abid R (2016)

     Excerpt The plant Cassia fistula (Caesalpiniaceae) fruit was widely used by traditional practitioners to treat cardiovascular diseases (CVDs) in India. RESULTS: Treatment with CFE at different doses has significantly restored the levels of serum lipid, MDA and enzymes activities in the liver and heart of hyperlipidemia mice.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.