Chrysophyllum camito (Kaymit) : medicinal properties in alcoholic extraction

Chrysophyllum camito (Kaymit, Caïmite) — family Sapotacées.

Scientific synonyms : Chrysophyllum Cainito var.martinicensis-Pierre (fruit mûr blanc), C.c. pomiferum-(Tussac)-Pierre (fruit mûr pourpre), Cainito pomiferum-Tussac, C.Cainito-Maza.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 9 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 35 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to KARUNAKAR H (2015)

     Excerpt KARUNAKAR H et al, evaluation of antidiabetic activity of hydroalcoholic extract of Chrysophyllum Caïmito fruit, Int J of Pharmaceut Sci & Res, 90 :24, 2015- ABSTRACT; Anti-diabetic activity of hydro-alcoholic extract of Chrysophyllum cainito fruits (CCE) was investigated against experimentally induced diabetics in rats using alloxan & streptozotocin (STZ). The present study concluded that CC fruits were found to be effective plant against alloxan & streptozotocin induced diabetes & also help in preservation of islet cells.

   • According to Guzman Ceferino J (2023)

     Excerpt The CC fruit was found to possess a free radical donor capacity & inhibitory activity of amylolytic enzyme, important in control of diabetes mellitus & its complications. The content of phenols & flavonoids, as well as antioxidant activity and in vitro antidiabetic activity, were determined for these extracts.

   • According to Hedge K (2016)

     Excerpt Hedge K et al, Evaluation of antidiabetic activity of hydro alcoholic extract of Chrysophyllum Caïmito fruits.

   • According to Yusip NI (2016)

     Excerpt Kenitu or star apple (Chrysophyllum cainito) is widely used as traditional remedy for inflammation, cancer, and diabetes mellitus.

   • According to Déciga-Campos M (2017)

     Excerpt The purpose of this work was to assess the antinociceptive & Antihyperalgesic properties of an herbal preparation, composed of four vegetal species: Pouteria Campechiana, Chrysophyllum cainito, Citrus Limonum, & Annona muricata, that is commonly used in combination (PCCA) in traditional Mayan medicine for the treatment of diabetes & pain. The PCCA extract (100–400 mg/kg, p.o.) had Antihyperalgesic effects in alloxan diabetic rats.

2. 2

   Cancer: chemopreventive treatment for resistant osteosarcoma

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Yusip NI (2016)

     Excerpt Kenitu or star apple (Chrysophyllum cainito) is widely used as traditional remedy for inflammation, cancer, and diabetes mellitus.

   • According to Doan HV (2020)

     Excerpt This study aimed to demonstrate anticancer properties of an aqueous extract from Chrysophyllum cainito stem bark (CE) & its underlying mechanisms. This is the first demonstration of the anticancer activity with proposed underlying mechanism of CE in liver cancer cells,.

   • According to Li LB (2015)

     Excerpt For production of reactive oxygen species in the Osteosarcoma cells, extract at 50 μg GAE/mL concentration was statistically equivalent to 100 μM H2O2. Osteosarcoma shows resistance to Chemotherapy & many side effects.

3. 3

   High blood pressure, fluid retention

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to -LI MM (2015)

     Excerpt Chrysophyllum cainito L., a traditional herbal medicine, could have the potential for management of hypertension due to presence of polyphenolic compounds. ALE-EAF reduced the elevated arterial pressure of salt induced hypertensive rat significantly to the level of normotensive animal group.

   • According to Mao LM (2015)

     Excerpt Mao LM et al, In vitro, ex vivo & in vivo antihypertensive activity of Chrysophyllum Caïmito L.

   • According to KARUNAKAR H (2015)

     Excerpt KARUNAKAR H et al, evaluation of antidiabetic activity of hydroalcoholic extract of Chrysophyllum Caïmito fruit, Int J of Pharmaceut Sci & Res, 90 :24, 2015- ABSTRACT; Anti-diabetic activity of hydro-alcoholic extract of Chrysophyllum cainito fruits (CCE) was investigated against experimentally induced diabetics in rats using alloxan & streptozotocin (STZ). Both the lower (200 mg/kg) & higher dose (400 mg/kg) of CCE showed a dose dependent significant decrease in blood glucose level, triglyceride, cholesterol levels & LDL & an increase in HDL in the treated diabetic rats when compared with diabetic control.

   • According to JANKHAM A (2024)

     Excerpt No significant differences among the treatments were observed in the survival rate, red blood cells, hematocrit, & hemoglobin (P >0.05). Star apple (Chrysophyllum cainito L.) has been used to treat several diseases.

   • According to Nguessan K (2009)

     Excerpt Nguessan K et al, Effect of aqueous extract of Chrysophyllum cainito leaves on the glycaemia of diabetic rabbits.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.